GenomeNet

Database: UniProt
Entry: A0A091PYI8_LEPDC
LinkDB: A0A091PYI8_LEPDC
Original site: A0A091PYI8_LEPDC 
ID   A0A091PYI8_LEPDC        Unreviewed;      1659 AA.
AC   A0A091PYI8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   10-MAY-2017, entry version 18.
DE   RecName: Full=Sodium channel protein {ECO:0000256|RuleBase:RU361132};
DE   Flags: Fragment;
GN   ORFNames=N330_04386 {ECO:0000313|EMBL:KFQ12338.1};
OS   Leptosomus discolor (Madagascar cuckoo roller) (Cuculus discolor).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Coraciiformes; Leptosomidae;
OC   Leptosomus.
OX   NCBI_TaxID=188344 {ECO:0000313|EMBL:KFQ12338.1, ECO:0000313|Proteomes:UP000053001};
RN   [1] {ECO:0000313|EMBL:KFQ12338.1, ECO:0000313|Proteomes:UP000053001}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N330 {ECO:0000313|EMBL:KFQ12338.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates the voltage-dependent sodium ion permeability
CC       of excitable membranes. {ECO:0000256|RuleBase:RU361132}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU361132}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- SIMILARITY: Belongs to the sodium channel (TC 1.A.1.10) family.
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU361132}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; KK680389; KFQ12338.1; -; Genomic_DNA.
DR   PhylomeDB; A0A091PYI8; -.
DR   Proteomes; UP000053001; Unassembled WGS sequence.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR008053; Na_channel_a5su.
DR   InterPro; IPR001696; Na_channel_asu.
DR   InterPro; IPR010526; Na_trans_assoc.
DR   InterPro; IPR024583; Na_trans_cytopl.
DR   Pfam; PF00520; Ion_trans; 4.
DR   Pfam; PF06512; Na_trans_assoc; 1.
DR   Pfam; PF11933; Na_trans_cytopl; 1.
DR   PRINTS; PR00170; NACHANNEL.
DR   PRINTS; PR01666; NACHANNEL5.
DR   SMART; SM00015; IQ; 1.
DR   PROSITE; PS50096; IQ; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000053001};
KW   Ion channel {ECO:0000256|RuleBase:RU361132,
KW   ECO:0000313|EMBL:KFQ12338.1};
KW   Ion transport {ECO:0000256|RuleBase:RU361132};
KW   Membrane {ECO:0000256|RuleBase:RU361132};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053001};
KW   Sodium {ECO:0000256|RuleBase:RU361132};
KW   Sodium channel {ECO:0000256|RuleBase:RU361132};
KW   Sodium transport {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361132};
KW   Transport {ECO:0000256|RuleBase:RU361132};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM     57     82       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    384    402       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    414    437       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    449    473       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    494    527       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    582    607       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    878    896       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    917    933       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    945    964       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1009   1029       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1119   1142       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1201   1219       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1231   1253       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1265   1284       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1332   1354       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM   1421   1444       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   DOMAIN        7     88       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      145    333       Na_trans_cytopl. {ECO:0000259|Pfam:
FT                                PF11933}.
FT   DOMAIN      384    611       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      621    872       Na_trans_assoc. {ECO:0000259|Pfam:
FT                                PF06512}.
FT   DOMAIN      876   1150       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN     1200   1454       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   COILED       79    113       {ECO:0000256|SAM:Coils}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFQ12338.1}.
FT   NON_TER    1659   1659       {ECO:0000313|EMBL:KFQ12338.1}.
SQ   SEQUENCE   1659 AA;  188799 MW;  63C708B62833BEF2 CRC64;
     CPEGYICLKA GENPDHGYTS FDTFGWAFLS LFRLMTQDCW ERLYQQTLRS AGKIYMLFFM
     LVIFLGSFYL VNLILAVVAM AYEEQNQATI AESEEKERKF REAMEMLRKE QEALAAKGID
     SVSLSSLEMS PLASKNAKER RNKRKKKKSL GAEEYGEDQR NPKCDYDDGQ RRMTLLGISY
     GPSANLVKRR TSHGSIFSFR LRGRDTGSET DFADDEISTA GENESHRGSL LIPRSGRRPS
     VQSQVSHSSH PTTPNYTQTG KRNSSVDCNG VVSLIGGGIG ALNPDPTSPA GLLLPPVIME
     KPGTGDLLLM PHCPSVDHSD EPFQRQRAVS AVSIITSALE ELEESHQKCP PCWNHFAVKF
     LIWDCCPLWL LIKKFVKFVV MDPFTDLTIT LCIVLNTLFM ALEHYKMTKE FDHMLYIGNL
     VFTGIFTAEM IFKVIALDPY YYFQQGWNIF DSIIVILSLM ELGLSSMGNL SVLRSFRLLR
     VFKLAKSWPT LNTLIKIIGN SVGALGNLTL VLAIIVFIFA VVGMQLFGKS YLDNVKKIST
     TGNLPRWHMN DFFHSFLIIF RILCGEWIET MWDCMEVAGQ PLCLLVFLLV MVIGNLVVLN
     LFLALLLSSF SADNLSAPDE DGEMNNLQLA FARINRGLQY VKRTTWDFCC NVLRHPKTTA
     EKKAMMKLAA QNTGALNNCV NSHTTAELGK DMENHKENHT EDVMNKNGEK HLRITDNDDF
     MTNPDLSICV PIAVGESDIE EEDEEQSTYT EMEQEKQLQL RGQRCQSPGV RSQNSEICEE
     LSELHVDKQL KAEPPPPVGQ KELDEISLSE GSTVDLTNPA ELLEQIPEFA EELMEPEDCF
     PEVCVRFFPC CSVDITKFPG KIWWRLRKTC YRIVEHNWFE TFIIFMILLS SGALAFEDIY
     LEDRKNIKTM LEYADKIFTY IFVLEMLLKW VAYGFKKYFT NAWCWLDFLI VDVSLISLIA
     NTLGYSEMGP IKSLRTLRAL RPLRALSRFE GMRVVVNALV GAIPSIMNVL LVCLIFWLIF
     SIMGVNLFAG KFGKCINKTE GDMPLDSKII NNMSDCILYN VSGTFYWTKV KVNFDNVGAG
     YLALLQVATF KGWMDIMYAA VDSRECEEQP EWEYNLYMYL YFVIFIIFGS FFTLNLFIGV
     IIDNFNQQKK KISGQDIFMT EEQKKYYNAM KKLGSKKPQK PIPRPLNKYQ GFIFDVVSKQ
     AFDVSIMILI CLNMITMMVE TDDQSQEKVN ILHKINMLFV AIFTGECIIK MLALRHYYFT
     NGWNIFDFVV VILSIVGTVL SDIIQKYFFS PTLFRVIRLA RIGRILRLIR GAKGIRTLLF
     ALMMSLPALF NIGLLLFLVM FIYAIFGMAN FAYVKKEHGI DDMFNFQTFA NSMLCLFQIT
     TSAGWDGLLN PILNTGPPYC DPNLPNANGS KGDCGSPAVG ILFFVTYIII SFLIVVNMYI
     AIILENFSVA TEESTEPLSE DDFDMFYEIW EKFDPEATQF IEYSALSDFA DALSEPLRIA
     KPNKIKLIAM DLPMVSGDRI HCLDILFAFT KRVLGESGEM DALKIQMEEK FMAANPSKIS
     YEPITTTLRR KQEEVSAIVI QRAYRRHLFR RSMKQASYLY RHRTFDGSIL EDDAPEKEGL
     IAFMMNENYG RPIDKSETLS STSFPPSYDS VTRGTSDNL
//
DBGET integrated database retrieval system