UniProt: A0A091QGT4

Database: UniProt
Entry: A0A091QGT4_MERNU

LinkDB:  A0A091QGT4_MERNU 
Original site:  A0A091QGT4_MERNU

All links

Ontology (5)   
   GO (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
DNA sequence (1)   
   EMBL (1)   
Protein domain (11)   
   InterPro (8)   
   Pfam (2)   
   PROSITE (1)   
All databases (18)   

Download RDF

ID   A0A091QGT4_MERNU        Unreviewed;       926 AA.
AC   A0A091QGT4;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 34.
DE   RecName: Full=isoleucine--tRNA ligase {ECO:0000256|ARBA:ARBA00013165};
DE            EC=6.1.1.5 {ECO:0000256|ARBA:ARBA00013165};
DE   AltName: Full=Isoleucyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00032665};
DE   Flags: Fragment;
GN   ORFNames=N331_12967 {ECO:0000313|EMBL:KFQ25873.1};
OS   Merops nubicus (Northern carmine bee-eater).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Coraciiformes; Meropidae; Merops.
OX   NCBI_TaxID=57421 {ECO:0000313|EMBL:KFQ25873.1, ECO:0000313|Proteomes:UP000052967};
RN   [1] {ECO:0000313|EMBL:KFQ25873.1, ECO:0000313|Proteomes:UP000052967}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N331 {ECO:0000313|EMBL:KFQ25873.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class-I aminoacyl-tRNA synthetase family.
CC       {ECO:0000256|ARBA:ARBA00005594, ECO:0000256|RuleBase:RU363035}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KK698582; KFQ25873.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091QGT4; -.
DR   Proteomes; UP000052967; Unassembled WGS sequence.
DR   GO; GO:0002161; F:aminoacyl-tRNA editing activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004822; F:isoleucine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0000049; F:tRNA binding; IEA:InterPro.
DR   GO; GO:0006428; P:isoleucyl-tRNA aminoacylation; IEA:InterPro.
DR   CDD; cd07960; Anticodon_Ia_Ile_BEm; 1.
DR   Gene3D; 1.10.730.20; -; 1.
DR   Gene3D; 3.40.50.620; HUPs; 2.
DR   Gene3D; 1.10.10.830; Ile-tRNA synthetase CP2 domain-like; 1.
DR   Gene3D; 3.90.740.10; Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain; 1.
DR   InterPro; IPR001412; aa-tRNA-synth_I_CS.
DR   InterPro; IPR002300; aa-tRNA-synth_Ia.
DR   InterPro; IPR033708; Anticodon_Ile_BEm.
DR   InterPro; IPR002301; Ile-tRNA-ligase.
DR   InterPro; IPR013155; M/V/L/I-tRNA-synth_anticd-bd.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR   InterPro; IPR009008; Val/Leu/Ile-tRNA-synth_edit.
DR   NCBIfam; TIGR00392; ileS; 1.
DR   PANTHER; PTHR42765:SF1; ISOLEUCINE--TRNA LIGASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR42765; SOLEUCYL-TRNA SYNTHETASE; 1.
DR   Pfam; PF08264; Anticodon_1; 1.
DR   Pfam; PF00133; tRNA-synt_1; 1.
DR   PRINTS; PR00984; TRNASYNTHILE.
DR   SUPFAM; SSF47323; Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases; 1.
DR   SUPFAM; SSF52374; Nucleotidylyl transferase; 1.
DR   SUPFAM; SSF50677; ValRS/IleRS/LeuRS editing domain; 1.
DR   PROSITE; PS00178; AA_TRNA_LIGASE_I; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW   ECO:0000256|RuleBase:RU363035};
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU363035};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000256|RuleBase:RU363035};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW   ECO:0000256|RuleBase:RU363035};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917,
KW   ECO:0000256|RuleBase:RU363035};
KW   Reference proteome {ECO:0000313|Proteomes:UP000052967}.
FT   DOMAIN          11..619
FT                   /note="Aminoacyl-tRNA synthetase class Ia"
FT                   /evidence="ECO:0000259|Pfam:PF00133"
FT   DOMAIN          667..786
FT                   /note="Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase
FT                   anticodon-binding"
FT                   /evidence="ECO:0000259|Pfam:PF08264"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFQ25873.1"
FT   NON_TER         926
FT                   /evidence="ECO:0000313|EMBL:KFQ25873.1"
SQ   SEQUENCE   926 AA;  103219 MW;  72E97140CC2BE43F CRC64;
     QKCGFSELYS WQRQRKTKQE FCLHDGPPYA NGDPHVGHAL NKILKDITNR FYVMRGYKVH
     YVPGWDCHGL PIELKALSEV RGAESLSPME IRQKAREFAE RAIEKQKSAF IRWGVMADWE
     NCYRTFDPKY EANQLKVFYK MYDKGFIYQD YKPVFWSPSA KTALAEAELE YNEQHVSRSV
     YVKFPLLKTP PKLTSAIDGS SPASVLVWTT QPWTVPANQA VCYMPDAAYS VVKCATTGEH
     FILAADRVES TAAALDTQFE VMSTCKGVDL ADGSCAHPTI PGRVSPLLPA NHVTMSKGTG
     LVHTAPAHGM EDYGVASHHQ LPTDCLVDEG GFFTEAAGPE LQNKNVLEEG NEAVIGMLQA
     AGSLLKEEKY VHSYPYDWRT KKPMIIRASK QWFVNTASVK AAAQEVLKKV KIIPTSAVNR
     MLEMLDRRTF WCISRQRCWG VPIPVFYQKN TGQCLINSES ITSVIKIVEQ QGTDAWWTLP
     IEQLLSKEAV AKAGGHDVLD YVKGQDVLDI WFDSGTSWAH VLEGAEQRAD TYLEGKDQLG
     GWFQSSLLTS VAARKKAPYK TLVVHGFTLG EKGEKMSKSI GNVVDPDVVI NGGEDHTRDP
     PYGADVLRWW VAESNVFTEV LIGPVVLNAA RDDINKLRNT LRFMLGNMAG FNPDTDSIPA
     SEMYIVDQYM LHLLQDYASK VTEAYKEYDY SKVVRLLQAF CSRNLSNFYF TLIKDRLYCE
     AARDAKRRSC QTVLAAALDA VVRSFAPILP HLAEEVFQHL PHGKDSEGVF RTGWINTSSA
     WKKPGIEEAI EGACAMRDSF LGAISGKNSL EYEVIIVIEP GLLFELMEAL QAEETSSVSQ
     LNELMMASQT TLLSELPKET PADANVIKGT FLINLEGGDI REESSYKVVA LPIAKAKCPR
     CRRYTSDSSS TPCPRCLKVL AGKGST
//

DBGET integrated database retrieval system