ID A0A091QK81_9GRUI Unreviewed; 648 AA.
AC A0A091QK81;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Integrin alpha-V {ECO:0000313|EMBL:KFQ27021.1};
DE Flags: Fragment;
GN ORFNames=N332_05415 {ECO:0000313|EMBL:KFQ27021.1};
OS Mesitornis unicolor (brown roatelo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Mesitornithidae; Mesitornis.
OX NCBI_TaxID=54374 {ECO:0000313|EMBL:KFQ27021.1, ECO:0000313|Proteomes:UP000053369};
RN [1] {ECO:0000313|EMBL:KFQ27021.1, ECO:0000313|Proteomes:UP000053369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N332 {ECO:0000313|EMBL:KFQ27021.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
CC -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC {ECO:0000256|ARBA:ARBA00008054, ECO:0000256|RuleBase:RU003762}.
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DR EMBL; KK798408; KFQ27021.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091QK81; -.
DR Proteomes; UP000053369; Unassembled WGS sequence.
DR GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR Gene3D; 2.60.40.1460; Integrin domains. Chain A, domain 2; 1.
DR Gene3D; 2.60.40.1510; ntegrin, alpha v. Chain A, domain 3; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR000413; Integrin_alpha.
DR InterPro; IPR013649; Integrin_alpha_Ig-like_1.
DR InterPro; IPR048285; Integrin_alpha_Ig-like_2.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR032695; Integrin_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF4; INTEGRIN ALPHA-V; 1.
DR Pfam; PF01839; FG-GAP; 3.
DR Pfam; PF08441; Integrin_A_Ig_1; 1.
DR Pfam; PF20805; Integrin_A_Ig_2; 1.
DR PRINTS; PR01185; INTEGRINA.
DR SMART; SM00191; Int_alpha; 4.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR SUPFAM; SSF69179; Integrin domains; 2.
DR PROSITE; PS51470; FG_GAP; 5.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW ECO:0000256|RuleBase:RU003762};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037, ECO:0000256|RuleBase:RU003762};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU003762};
KW Reference proteome {ECO:0000313|Proteomes:UP000053369};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT REPEAT 47..108
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 139..193
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 194..259
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 260..317
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 321..384
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT DOMAIN 369..525
FT /note="Integrin alpha first immunoglubulin-like"
FT /evidence="ECO:0000259|Pfam:PF08441"
FT DOMAIN 526..648
FT /note="Integrin alpha second immunoglobulin-like"
FT /evidence="ECO:0000259|Pfam:PF20805"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ27021.1"
FT NON_TER 648
FT /evidence="ECO:0000313|EMBL:KFQ27021.1"
SQ SEQUENCE 648 AA; 71272 MW; 2E514427EFA50C7A CRC64;
RIFLLVGAPK ANTTQHNIVE GGQVLKCNWN SNRNCQPIIF DSTGNRDFAP DDPLEFKSHQ
WFGASVRSKN DKILACAPLY HWRTETKQER EPVGTCYLLA GSKSVEYAPC RSSQLISDRV
TEIVAKYNPK VYSTKYDDQL ATRPASAAFD DSYLGYSVAV GDFSGDGIED FVSGVPRAAR
TLGMVSIYNG KNMSSMYNFT GEQMAAYFGY SVAATDINGD NYTDLFIGAP LFMDRGSDGK
LQEVGQVSIC LQRPSGGFQI TKLNGFEIFA RFSSSFAPLG DLDQDGFNDI AIAAPYGGED
KRGLVYIYNG RANGLNAVPS QILEGQWAAH TMPPSFGYSL KGATDVDKNG YPDLIVGAFG
VDTAVLYRAR PVIRVNAALE VNPTILNPEN KACSLSDVKV SCFKVKFCLK ADGKGKLPNS
LNFQVELLLD KLKQKGAIRR ALFLHSKQPS HSKNMTITNG GKMNCEELDA FLRGESEFRD
KLTPITIFME YRLDYRTAAD ATGLHPILNQ FTPANMSRQA HILLDCGDDN ICKPKLEVSV
ESDQKQIYIG DDNPLTLIVS VQNQGEGAYE AELFVIVPPQ ADFIGVVRNN EALARLSCAF
KTENQTRMVV CDLGNPMKAG TKILAGLRFS VHQQSEMDTS VKFALQIR
//
