ID A0A091QZF5_MERNU Unreviewed; 1302 AA.
AC A0A091QZF5;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Low-density lipoprotein receptor-related protein 6 {ECO:0000313|EMBL:KFQ32915.1};
DE Flags: Fragment;
GN ORFNames=N331_08599 {ECO:0000313|EMBL:KFQ32915.1};
OS Merops nubicus (Northern carmine bee-eater).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Meropidae; Merops.
OX NCBI_TaxID=57421 {ECO:0000313|EMBL:KFQ32915.1, ECO:0000313|Proteomes:UP000052967};
RN [1] {ECO:0000313|EMBL:KFQ32915.1, ECO:0000313|Proteomes:UP000052967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N331 {ECO:0000313|EMBL:KFQ32915.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR EMBL; KK710375; KFQ32915.1; -; Genomic_DNA.
DR Proteomes; UP000052967; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0009653; P:anatomical structure morphogenesis; IEA:UniProt.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR CDD; cd00112; LDLa; 3.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 3.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 4.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR46513:SF40; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 6; 1.
DR PANTHER; PTHR46513; VITELLOGENIN RECEPTOR-LIKE PROTEIN-RELATED-RELATED; 1.
DR Pfam; PF14670; FXa_inhibition; 4.
DR Pfam; PF00057; Ldl_recept_a; 3.
DR Pfam; PF00058; Ldl_recept_b; 8.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00181; EGF; 4.
DR SMART; SM00192; LDLa; 3.
DR SMART; SM00135; LY; 16.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR SUPFAM; SSF57424; LDL receptor-like module; 3.
DR SUPFAM; SSF63825; YWTD domain; 4.
DR PROSITE; PS01209; LDLRA_1; 2.
DR PROSITE; PS50068; LDLRA_2; 3.
DR PROSITE; PS51120; LDLRB; 11.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Lipoprotein {ECO:0000313|EMBL:KFQ32915.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KFQ32915.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000052967};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1161..1181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 72..111
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT REPEAT 159..201
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 202..244
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 245..288
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 289..331
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 378..415
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT REPEAT 461..503
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 504..546
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 547..589
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 630..672
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 679..717
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT REPEAT 813..855
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 856..900
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 901..943
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 993..1037
FT /note="EGF-like"
FT /evidence="ECO:0000259|SMART:SM00181"
FT REGION 1244..1283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1252..1268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 1057..1072
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1075..1087
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1082..1100
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1094..1109
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1113..1125
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1120..1138
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1132..1147
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ32915.1"
FT NON_TER 1302
FT /evidence="ECO:0000313|EMBL:KFQ32915.1"
SQ SEQUENCE 1302 AA; 145358 MW; 587B486D2A3C022F CRC64;
SARQAVVKGS LPHPFALTLF GDTLYWTDWN THSILACSKY SGEDLREVHS NIFSPMDIHA
FSQKRQPNAT NPCGINNGGC SHLCLMSPTK PSYQCACPTG VKLLENGKTC KDGATELLLL
ARRTDLRRIS LDPPDFTDIV LPLEDIRHAI AIDFDPLEGY IYWTDDEVRA IRRAGLDGAG
SQVVVTAQIA HPDGIAVDWV ARNLYWTDTG TDRIEVTRLN GTMRKILISE DLEEPRAIVL
DPMVGYMYWT DWGEIPKIER AALDGSDRIV LVNTSLGWPN GLALDYAESK IYWGDAKTDK
IEVMNADGTG RRVLVEDKLP HIFGFTLLGD YVYWTDWQRR SIERVHKRTA EREIIIDQLP
DLMGLKATNV HQIMGTTPWA EENGGCSHLC LYRPQGLRCA CPIGLELISD MRTCIVPEAF
LLFSRRADIR RISLETNNNN VAIPLTGVKE ASALDFDVTD NRIYWTDISL KTISRAFMNG
SALEHVVEFG LDYPEGMAVD WLGKNLYWAD TGTNRIEVSK LDGQHRQVLV WKDLDSPRAL
ALDPAEGFMY WTEWGGKPKI DRAAMDGSER TTLVPNVGRA NGLTIDYAKR RLYWTDLDTN
LIESSNMLGL DREIIADDLP HPFGLTQYQD YIYWTDWSRR SIERANKTSG QNRTIIQGHL
DYVMDILVFH SSRQAGWNEC ASSNGHCSHL CLAVPVGGFV CGCPAHYSLN SDNRTCSAPT
TFLLFSQKNA INRMVIDEQQ SPDIILPIHS LRNVRAIDYD PLDKQLYWID SRQNIIRKAQ
EDGSQSLTVV TSPVPNQNLE MQPYDLSIDI YSRYIYWTCE ATNVINVTRL DGRPMGVVLR
GDQDRPRAIV VNPEKGYMYF TNLQERSPKI ERAALDGTER EVLFFSGLSK PVALAIDSQL
GKLFWADSDL RRIESSDLSG ANRIVLEDSN ILQPVGLTVF ENWLYWIDRQ QQMIEKIDMT
GREGRTKVQA RIAQLSDIHA VKELNLQEYR QHPCSQDNGG CSHICIVKGD GTTRCSCPVH
LVLLQDELSC GEPPTCSPQQ FTCFTGEIDC IPVAWRCDGF TECEDHSDEK NCPVCSDSQF
QCESGQCIDS ALRCNGEANC QDNSDEKNCE VLCLTDQFRC ASGQCIGKSK KCDHNLDCSD
SSDEQGCYTT EEPAPQPNNT IGSIIGVILT VFVVGAMYFI CQRVLCPRMK GDGETMTNDY
VVHGPASVPL GYVPHPSSLS GSLPGMSRGK SVISSLSIMG GSSGPPYDRA HVTGASSSSS
SSTKGTYFPP ILNPPPSPAT ERSHYTMEFG YSSNSPSTHR SY
//
