ID A0A091R5R8_MERNU Unreviewed; 435 AA.
AC A0A091R5R8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=tRNA (guanine(10)-N2)-methyltransferase homolog {ECO:0000256|ARBA:ARBA00013960};
DE AltName: Full=tRNA guanosine-2'-O-methyltransferase TRM11 homolog {ECO:0000256|ARBA:ARBA00032604};
DE Flags: Fragment;
GN ORFNames=N331_07680 {ECO:0000313|EMBL:KFQ21971.1};
OS Merops nubicus (Northern carmine bee-eater).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Meropidae; Merops.
OX NCBI_TaxID=57421 {ECO:0000313|EMBL:KFQ21971.1, ECO:0000313|Proteomes:UP000052967};
RN [1] {ECO:0000313|EMBL:KFQ21971.1, ECO:0000313|Proteomes:UP000052967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N331 {ECO:0000313|EMBL:KFQ21971.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalytic subunit of an S-adenosyl-L-methionine-dependent
CC tRNA methyltransferase complex that mediates the methylation of the
CC guanosine nucleotide at position 10 (m2G10) in tRNAs.
CC {ECO:0000256|ARBA:ARBA00002425}.
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DR EMBL; KK691889; KFQ21971.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091R5R8; -.
DR Proteomes; UP000052967; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR016691; tRNA_mtfrase_TRM11.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR PANTHER; PTHR13370:SF3; TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG; 1.
DR Pfam; PF01170; UPF0020; 1.
DR PIRSF; PIRSF017259; tRNA_mtfrase_TRM11; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51627; SAM_MT_TRM11; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KFQ21971.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000052967};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022555};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KFQ21971.1};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT DOMAIN 165..297
FT /note="UPF0020"
FT /evidence="ECO:0000259|Pfam:PF01170"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ21971.1"
FT NON_TER 435
FT /evidence="ECO:0000313|EMBL:KFQ21971.1"
SQ SEQUENCE 435 AA; 50054 MW; FC2DFBBE4C095271 CRC64;
EITSLLSLYG GQFSGEREIC VNSPFWILSI PSEEMARGLM KRTVCAKSIF ELWGHGRSAG
ELYASLRNYP EHKMLPYLQA DSTYKVHIHT FNKTLTQAQK IEKIDALEFL PFKGKVNLKN
PEHIFWILED YGMDPNNAPE EPFHLYFGRW VHGQRELIES YSVKKRHFIG NTSMDACLSF
IMANHGRVKP NDLVYDPFVG TGGLLISSAH FGAYVCGTDI DYNTIHGLGK ASRKNQKWRG
PDENIRANLC QYGLEKYYLD ALVSDSSRPI WRKGMLFDAI ITDPPYGIRE ATRRTGSQKE
TVKSAERSTE NHIFVSSSYH LSDIFCDLLK FAAEYLVMGG RLVFWLPVYK PEYTEDIIPC
HPCLKLISNC EQMLSSHTSR RLITMEKVKE FKDQDQNSCL LEGQYMPYRG HNSFREKYFS
GVTKRIAKEE KDNQK
//
