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Database: UniProt
Entry: A0A091RGX1_9GRUI
LinkDB: A0A091RGX1_9GRUI
Original site: A0A091RGX1_9GRUI 
ID   A0A091RGX1_9GRUI        Unreviewed;       514 AA.
AC   A0A091RGX1;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   10-MAY-2017, entry version 19.
DE   RecName: Full=Sodium channel protein {ECO:0000256|RuleBase:RU361132};
DE   Flags: Fragment;
GN   ORFNames=N332_04935 {ECO:0000313|EMBL:KFQ38532.1};
OS   Mesitornis unicolor (brown roatelo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Gruiformes; Mesitornithidae;
OC   Mesitornis.
OX   NCBI_TaxID=54374 {ECO:0000313|EMBL:KFQ38532.1, ECO:0000313|Proteomes:UP000053369};
RN   [1] {ECO:0000313|EMBL:KFQ38532.1, ECO:0000313|Proteomes:UP000053369}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N332 {ECO:0000313|EMBL:KFQ38532.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates the voltage-dependent sodium ion permeability
CC       of excitable membranes. {ECO:0000256|RuleBase:RU361132}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU361132}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- SIMILARITY: Belongs to the sodium channel (TC 1.A.1.10) family.
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU361132}.
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DR   EMBL; KK816713; KFQ38532.1; -; Genomic_DNA.
DR   Proteomes; UP000053369; Unassembled WGS sequence.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   InterPro; IPR031649; GPHH_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR001696; Na_channel_asu.
DR   Pfam; PF16905; GPHH; 1.
DR   Pfam; PF00520; Ion_trans; 2.
DR   PRINTS; PR00170; NACHANNEL.
DR   SMART; SM00015; IQ; 1.
DR   PROSITE; PS50096; IQ; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053369};
KW   Ion channel {ECO:0000256|RuleBase:RU361132,
KW   ECO:0000313|EMBL:KFQ38532.1};
KW   Ion transport {ECO:0000256|RuleBase:RU361132};
KW   Membrane {ECO:0000256|RuleBase:RU361132};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053369};
KW   Sodium {ECO:0000256|RuleBase:RU361132};
KW   Sodium channel {ECO:0000256|RuleBase:RU361132};
KW   Sodium transport {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361132};
KW   Transport {ECO:0000256|RuleBase:RU361132};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM      6     25       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM     92    110       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    122    140       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    152    175       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    209    237       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    313    336       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   DOMAIN        2     33       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN       91    346       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      350    393       GPHH. {ECO:0000259|Pfam:PF16905}.
FT   NON_TER     514    514       {ECO:0000313|EMBL:KFQ38532.1}.
SQ   SEQUENCE   514 AA;  58900 MW;  9A1E31943C3CF443 CRC64;
     MYIYFVAFII FGSFFTLNLF IGVIIDNFNQ QKKKIILFLL FYLGGQDIFM TEEQKKYYNA
     MKKLGSKKPQ KPIPRPANKL QGLVFDIVTK QAFDITIMIL ICLNMVTMMI ETDDQSELMQ
     NILYRINLVF VVLFTGECVF KMFSLRCYYF TIGWNIFDFV VVILSIVGMC LANMIEKYFV
     SPTLFRVVRL ARIGRILRLI KGAKGIRTLL FALMMSLPAL FNIGLLLFLV MFIYAIFGMS
     NFAYVKREAG IDDMFNFETF GNSMICLFQI TTSAGWDLLL SPILNSGEPD CDPNKAHPGS
     SVKGDCGNPS VGIFFFVSYI IISFLVVVNM YIAVILENFS VATEESAEPL SEDDFEMFYE
     VWEKYDPDAT QFIEYTKLSD FAASLDPPLL IPKPNKVQLI AMDLPMVSGD RIHCLDILFA
     FTKRVLGDSD EMDSLRIQME DRFMAANPSK ASYEPITTTL KRKQEEVSAA IIQRAYRCYL
     LRQSVKKLLF MYRNDGVDLL FKKDTIIGKR SENS
//
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