ID A0A091RIR6_9GRUI Unreviewed; 1763 AA.
AC A0A091RIR6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Myosin-6 {ECO:0000313|EMBL:KFQ39436.1};
DE Flags: Fragment;
GN ORFNames=N332_02819 {ECO:0000313|EMBL:KFQ39436.1};
OS Mesitornis unicolor (brown roatelo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Gruiformes; Mesitornithidae; Mesitornis.
OX NCBI_TaxID=54374 {ECO:0000313|EMBL:KFQ39436.1, ECO:0000313|Proteomes:UP000053369};
RN [1] {ECO:0000313|EMBL:KFQ39436.1, ECO:0000313|Proteomes:UP000053369}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N332 {ECO:0000313|EMBL:KFQ39436.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Muscle contraction. {ECO:0000256|ARBA:ARBA00037488}.
CC -!- SUBUNIT: Muscle myosin is a hexameric protein that consists of 2 heavy
CC chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2
CC regulatory light chain subunits (MLC-2).
CC {ECO:0000256|ARBA:ARBA00038612}.
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|ARBA:ARBA00008314,
CC ECO:0000256|PROSITE-ProRule:PRU00782}.
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DR EMBL; KK819205; KFQ39436.1; -; Genomic_DNA.
DR Proteomes; UP000053369; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0051015; F:actin filament binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd01377; MYSc_class_II; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.340; -; 5.
DR Gene3D; 1.20.5.370; -; 5.
DR Gene3D; 1.20.5.4820; -; 1.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 2.30.30.360; Myosin S1 fragment, N-terminal; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR004009; Myosin_N.
DR InterPro; IPR008989; Myosin_S1_N.
DR InterPro; IPR002928; Myosin_tail.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014751; XRCC4-like_C.
DR PANTHER; PTHR45615; MYOSIN HEAVY CHAIN, NON-MUSCLE; 1.
DR PANTHER; PTHR45615:SF11; MYOSIN-6; 1.
DR Pfam; PF00063; Myosin_head; 1.
DR Pfam; PF02736; Myosin_N; 1.
DR Pfam; PF01576; Myosin_tail_1; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF90257; Myosin rod fragments; 5.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50096; IQ; 1.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
DR PROSITE; PS51844; SH3_LIKE; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000053369}.
FT DOMAIN 30..79
FT /note="Myosin N-terminal SH3-like"
FT /evidence="ECO:0000259|PROSITE:PS51844"
FT DOMAIN 83..778
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT REGION 655..677
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT COILED 840..1156
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1200..1761
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 176..183
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT NON_TER 1763
FT /evidence="ECO:0000313|EMBL:KFQ39436.1"
SQ SEQUENCE 1763 AA; 202963 MW; B396CBF808D0C348 CRC64;
MMDMTEFGEA APFLRKSEKE LMMAQTVAFD GKKKCWVPDD KKAYVEAEIT ETSGGKVTVQ
TTDGKTMTIK EDDVQSMNPP KFDMIEDMAM LTHLNEASVL YNLRKRYSNW MIYTYSGLFC
VTINPYKWLP VYKPEVVAAY KGKRRSEAPP HIFSIADNAY HDMLRNRENQ SMLITGESGA
GKTVNTKRVI QYFATVAALG EPGKKTVSLL EDGTLEDQII QANPALEAFG NAKTLRNDNS
SRFGKFIRIH FGTTGKLSSA DIEIYLLEKS RVIFQQPGER DYHIFYQILS GKKPELLDML
LVSTNPYDYH FCSQGVVTVD NLDDGEELLA TDQAMDILGF VPDEKSGSYK LTGAIMHFGN
MKFKQRPREE QAEADGTESA DKAAYLMGIN SSDLIKGLLH PRVKVGNEYV TKGQSVEQVL
YAVGALSKAV YDRMFKWLVV RINKTLDTKL PRQFFIGVLD IAGFEIFDFN SFEQLCINYT
NEKLQQFFNH HMFVLEQEEY KKEGIEWVFI DFGMDLQACI DLIEKPLGIL SILEEECMFP
KATDMTFKAK LYDNHLGKSP NLQKPRPDKK RKYEAHFELL HYAGAVPYNI IGWLEKNKDP
LNETVVGIFQ KSSNKLLASL FESYVGADSA DQGGEKKRKK GASFQTVSSL HKENLNKLMT
NLKSTAPHFV RCIIPNESKT PGEMDAFLVL HQLRCNGVLE GIRICRKGFP NRVLYADFKQ
RYRILNPGAI PEDKFVDSRK AAEKLLASLD VDHNQYRFGH TKVFFKAGLL GHLEEMRDER
LAKILTMIQA RARGRLMRIE FQKIVERRDA LLVIQWNIRA FMAVKNWPWM KLFFKIKPLL
KSAETEKEMA NMKEEFLKLK EALEKSEARR KELEEKQVSL VQEKNDLLLQ LQAEQDTLAD
AEERCDLLIK SKIQLEAKVK ELTERVEDEE EMNSELTSKK RKLEDECSEL KKDIDDLEIT
LAKVEKEKHA TENKVKNLTE EMAALDENIS KLTKEKKSLQ EAHQQVLDDL QAEEDKVNTL
SKAKVKLEQQ VDDLEGSLEQ EKKVRMDLER AKRKLEGDLK LTQESVMDLE NDKLQMEEKL
KKKEFEMSQL NSKIEDEQAI VMQLQKKIKE LQARIEELEE ELEAERAARA KVEKQRSDLA
RELEELSERL EEAGGATAAQ LEMNKKREAE FLKLRRDLEE ATLHYEATAA TLRKKHADSV
AEMGEQLDNL QRVKQKLEKE KSELKMEVDD LSSNMEQMVK GKANAEKLCR TYEDHLNETK
TKLEEMTRLM NDLTTQKTKL QSENGEFIRQ LEEKESLISQ LSRGKTSFTQ QIEELRRQLE
EETKSKNALA HALQAARHDC DLLREQYEEE QEAKAELQRA LSKGNAEVAQ WRTKYETDAI
QRTEELEDAK KKLAARLQEA EEAIEAANAK CSSLEKTKHR LQNELEDMMI DLEKANSAAA
SLDKKQRGFD KIINDWKQKY EESQAELEAS QKEARGLSTE LFKLKNAYEE TLDHLETLKR
ENKNLQEEIS DLTNQISEGN KSLHEIEKIK KQVEQEKSEV QLALEEAEGA LEHEESKTLR
FQLELSQLKA EFERKLTEKE EEMENIRRNQ QRAIDSLQST LDSEARSRNE AIRLKKKMEG
DLNEMEIQLS HANRHAAEAT KSARVLQAQI KELQVQLDDS GHMNEDLKEQ LAVSDRRNNL
LQSELDELRA LLDQTERARK LAEHELLEAT ERVNLLHTQN TSLINQKKKL EGDISQMQNE
VEESIQECRN AEEKAKKAIT DVS
//
