ID A0A091RRP3_MERNU Unreviewed; 552 AA.
AC A0A091RRP3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 13-SEP-2023, entry version 33.
DE SubName: Full=Merlin {ECO:0000313|EMBL:KFQ31132.1};
DE Flags: Fragment;
GN ORFNames=N331_03199 {ECO:0000313|EMBL:KFQ31132.1};
OS Merops nubicus (Northern carmine bee-eater).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Coraciiformes; Meropidae; Merops.
OX NCBI_TaxID=57421 {ECO:0000313|EMBL:KFQ31132.1, ECO:0000313|Proteomes:UP000052967};
RN [1] {ECO:0000313|EMBL:KFQ31132.1, ECO:0000313|Proteomes:UP000052967}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N331 {ECO:0000313|EMBL:KFQ31132.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Membrane
CC {ECO:0000256|ARBA:ARBA00004287}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004287}; Cytoplasmic side
CC {ECO:0000256|ARBA:ARBA00004287}.
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DR EMBL; KK707228; KFQ31132.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091RRP3; -.
DR Proteomes; UP000052967; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13194; FERM_C_ERM; 1.
DR Gene3D; 1.20.5.450; -; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR011174; ERM.
DR InterPro; IPR011259; ERM_C_dom.
DR InterPro; IPR041789; ERM_FERM_C.
DR InterPro; IPR046810; ERM_helical.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR008954; Moesin_tail_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23281:SF20; FERM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23281; MERLIN/MOESIN/EZRIN/RADIXIN; 1.
DR Pfam; PF00769; ERM_C; 1.
DR Pfam; PF20492; ERM_helical; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR PIRSF; PIRSF002305; ERM; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF48678; Moesin tail domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000052967}.
FT DOMAIN 14..304
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT COILED 311..471
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 517..544
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 68..71
FT /ligand="a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-
FT inositol)"
FT /ligand_id="ChEBI:CHEBI:57880"
FT /evidence="ECO:0000256|PIRSR:PIRSR002305-1"
FT BINDING 287
FT /ligand="a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-
FT inositol)"
FT /ligand_id="ChEBI:CHEBI:57880"
FT /evidence="ECO:0000256|PIRSR:PIRSR002305-1"
FT NON_TER 552
FT /evidence="ECO:0000313|EMBL:KFQ31132.1"
SQ SEQUENCE 552 AA; 65200 MW; 47C9240040296D52 CRC64;
MSIRGLKKKQ PKTFKVKVIT VDAELEFSCE MKWKGKDLFD LVCRALGLRE TWFFGLQYTI
KGMCTWLKMD KKVLDQEIPK EDPISFHFLA KFYPEKVEEE LLQEITQHLF FLQVKKQILD
EEIYCSPEAT VLLASYAVQA KYGDYDPNFH EPGFLAHDEL LPKRVLRQYQ LTAEMWEEKI
TAWYAEHRGI ARDEAEMNYL KIAQDLEMYG VNYFPIAQNK NHTDLLLGVD AKGIHIYSIN
NRFSPNKSFE WSAIRNISYS EKELTIKPLD KKAEVFKFFS SQLKVNKLIL QLCIGNHDLF
MRRRKVDSIE IQQMKAQARE EKARKKMENQ RLAREKQLRE EAERAKEELE RRLFQLEDEA
RQANEALLRS QEAAELLAEK AQIAEEEAKL LAQNAAEAEQ ERQRLEITAL KTKEEKRLME
QKMREAELIA VKLVKESDRR AKEAEHLKQD LHEAREAERK AKQKLLDLTR LNYPHMAKYP
QYSPPDTRDA NFDKGSIKLD LKDIDLKRLS FEIERERLDY LEKSRKFEDR LKELKSEIHA
LKLEEKQAGL YS
//
