ID A0A091RT86_NESNO Unreviewed; 435 AA.
AC A0A091RT86;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=tRNA (guanine(10)-N2)-methyltransferase homolog {ECO:0000256|ARBA:ARBA00013960};
DE AltName: Full=tRNA guanosine-2'-O-methyltransferase TRM11 homolog {ECO:0000256|ARBA:ARBA00032604};
DE Flags: Fragment;
GN ORFNames=N333_08941 {ECO:0000313|EMBL:KFQ45880.1};
OS Nestor notabilis (Kea).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Nestor.
OX NCBI_TaxID=176057 {ECO:0000313|EMBL:KFQ45880.1, ECO:0000313|Proteomes:UP000053840};
RN [1] {ECO:0000313|EMBL:KFQ45880.1, ECO:0000313|Proteomes:UP000053840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N333 {ECO:0000313|EMBL:KFQ45880.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalytic subunit of an S-adenosyl-L-methionine-dependent
CC tRNA methyltransferase complex that mediates the methylation of the
CC guanosine nucleotide at position 10 (m2G10) in tRNAs.
CC {ECO:0000256|ARBA:ARBA00002425}.
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DR EMBL; KK932954; KFQ45880.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091RT86; -.
DR Proteomes; UP000053840; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0000049; F:tRNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR016691; tRNA_mtfrase_TRM11.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR PANTHER; PTHR13370:SF3; TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG; 1.
DR Pfam; PF01170; UPF0020; 1.
DR PIRSF; PIRSF017259; tRNA_mtfrase_TRM11; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51627; SAM_MT_TRM11; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:KFQ45880.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053840};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022555};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KFQ45880.1};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT DOMAIN 165..297
FT /note="UPF0020"
FT /evidence="ECO:0000259|Pfam:PF01170"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ45880.1"
FT NON_TER 435
FT /evidence="ECO:0000313|EMBL:KFQ45880.1"
SQ SEQUENCE 435 AA; 50233 MW; 7C82F09C2BEAFABD CRC64;
EIKSLLSLSG GQFSGEQEIR VNSPFWILNI PSEEMARGLM KRTVCAKSIF ELWGHGRSAG
ELYASLKNYP VDKMLPYLQS DSTYKVHIHT FNKTLTQAQK IKKIDALEFL PFKGKVNLKK
PEHIFWILED YGMDPNNVPE EPFHLYFGRW VHGQRELIES YSVKKRHFIG NTSMDACLSF
IMANHGRVKP NDVVYDPFVG TGGLLISSAH FGAYVCGTDI DYNTIHGLGK ATRKNQKWRG
PDENIRANLR QYGLEKYYLD ALVSDSSRPI WRKGMLFDAI ITDPPYGIRE ATRRTGSQKE
TVKTAERSTE NHVFVSSSYH LSDIFFDLLK FAAEYLVMGG RLVYWLPIYR PEYTEEIIPC
HPCLKLISNS EQMLSSHTSR RLITMEKVKE FKDQDQNSYL LDGQYMPYRG HNSFREKYFS
GVTKRIAKEE KDNQK
//
