ID   A0A091S5Z1_NESNO        Unreviewed;      1305 AA.
AC   A0A091S5Z1;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   22-FEB-2023, entry version 44.
DE   SubName: Full=Protein very KIND {ECO:0000313|EMBL:KFQ51723.1};
DE   Flags: Fragment;
GN   ORFNames=N333_01850 {ECO:0000313|EMBL:KFQ51723.1};
OS   Nestor notabilis (Kea).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Nestor.
OX   NCBI_TaxID=176057 {ECO:0000313|EMBL:KFQ51723.1, ECO:0000313|Proteomes:UP000053840};
RN   [1] {ECO:0000313|EMBL:KFQ51723.1, ECO:0000313|Proteomes:UP000053840}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N333 {ECO:0000313|EMBL:KFQ51723.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KK942371; KFQ51723.1; -; Genomic_DNA.
DR   Proteomes; UP000053840; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd06224; REM; 1.
DR   Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR   Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR   Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR011019; KIND_dom.
DR   InterPro; IPR029899; KNDC1.
DR   InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR   InterPro; IPR023578; Ras_GEF_dom_sf.
DR   InterPro; IPR001895; RASGEF_cat_dom.
DR   InterPro; IPR036964; RASGEF_cat_dom_sf.
DR   PANTHER; PTHR21560:SF0; KINASE NON-CATALYTIC C-LOBE DOMAIN-CONTAINING PROTEIN 1; 1.
DR   PANTHER; PTHR21560; VERY KIND PROTEIN; 1.
DR   Pfam; PF00617; RasGEF; 1.
DR   Pfam; PF00618; RasGEF_N; 1.
DR   SMART; SM00750; KIND; 1.
DR   SMART; SM00147; RasGEF; 1.
DR   SMART; SM00229; RasGEFN; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   SUPFAM; SSF48366; Ras GEF; 1.
DR   PROSITE; PS51377; KIND; 1.
DR   PROSITE; PS50009; RASGEF_CAT; 1.
DR   PROSITE; PS50212; RASGEF_NTER; 1.
PE   4: Predicted;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW   ECO:0000256|PROSITE-ProRule:PRU00168};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053840};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          6..170
FT                   /note="KIND"
FT                   /evidence="ECO:0000259|PROSITE:PS51377"
FT   DOMAIN          799..924
FT                   /note="N-terminal Ras-GEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50212"
FT   DOMAIN          1024..1275
FT                   /note="Ras-GEF"
FT                   /evidence="ECO:0000259|PROSITE:PS50009"
FT   REGION          259..283
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          595..618
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        595..613
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFQ51723.1"
FT   NON_TER         1305
FT                   /evidence="ECO:0000313|EMBL:KFQ51723.1"
SQ   SEQUENCE   1305 AA;  147477 MW;  D0D31E69663E7ECA CRC64;
     FLFQWISLKI LLSWYGKPLK DYELWALCHE CLCTLQTCGD YPVVLCLDSV LIDCHGSILF
     AAPKAEESCD IFYLAPEIEE EYVDTEKVCV YGVAAVLWMA AKSSVPPSHK LALPRKFKKL
     LLDMARRNPE ERPSLADAIK TCSRYLFEQG VNSKNILALL NKSVFKAVEE DIMSSQDHVA
     FAFKNERHEM DPSESSLGFV PVTSASKLVA VKGPVPCQIS LNCEKATLPV AFTSPATHFK
     PIILQQNENI TKEVHTPVSE QFKKETRKEK HADNNKSGFT EDFKSCGTED TDVPAPEIHE
     CGLQVPGHSS QISSEEQKPG NACTSVVTLP SPSDSSHILQ EKSILPEVPS NSAACPTSPN
     FLHINNIILK QDSEKRVTTF VPVHLAVSEQ IPNKPLRSRI AYDCCHNSIF TEQGYIPCTS
     VNQENSHLFN AEVLPQQNRT SDTLLQEVVH LIQEEFAFDG YLENGVEVFD MGNFILNLKE
     IQFRIFSDRI CEKFCDLYWD EKLLENLYRV VNGERPSHLC IMPTFDCLLC PLSKTCITAH
     DCYFFPPHTP SLGEGEAAFD VKAEPMINTS LAEMEFDESP SDNIKKELRL HNTAPSEKEQ
     QCLQGNGSCT DPGFAEENTE PEEETMMKIA GNSYLVSPNL SDFHGCSPGW SSAFYGAECF
     DSEVHRYMKN LGKQKSSESQ NIDAKKVELE QLLMMETKNY RKTIKFYQKL LQKERSSKGL
     ETKSVLPKLR EQLQEMKSKV QFLELVKKYV QAKQWGVESC VLPTVIHNGR INTVDVTPDE
     SSVLLYYNTE KHQCNNQNGI RVLQAGTPLG LMAYLYSRNA FLEGYVQQFL YTFRYFCTQE
     EFLQFLLDRI SSTLSSASLD PSTSLTKICN RSFYILQAWI EDCYSVDFAT NTDLLCTLKE
     FISSKVAPLN GYGERLLSLL EDASARKSGS AHQSSSMDKC EEEGEEDRKT LHSLCKKLSE
     DVSRKNFNWK LSKGVGPIAQ YQRERLYTSS SVLPKPCYNS FREEFPVSFT KSDEVGPYLL
     IEYSVQELCC QLTLLQQEVF HKCHPVHFLN SRALGVKDKC VSVQKAVSAE TVSFKVCNLF
     LSKCIQDQYL LQLLSNADSV STWVAAEIVT CHTSKLQVSL LSKFLLIAKG CYEQRNFATA
     MQILSGLENL IVRQLPAWKI LPAKVAEIME ELKAVEVFLK SDSLCLMEGG RYKTLPTIPS
     AHVLAMHVQQ LETGGFTMTN GAHKWTKLRN IAKVVSQVHA FQENPYTYTP DFKLQSYLRQ
     RITRFKDADV SVLAADNCAN FHQIPAEKHS RKIQDTLRRM KATFQ
//