ID A0A091S9Q8_NESNO Unreviewed; 2307 AA.
AC A0A091S9Q8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
DE Flags: Fragment;
GN ORFNames=N333_11170 {ECO:0000313|EMBL:KFQ54042.1};
OS Nestor notabilis (Kea).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Psittaciformes; Psittacidae; Nestor.
OX NCBI_TaxID=176057 {ECO:0000313|EMBL:KFQ54042.1, ECO:0000313|Proteomes:UP000053840};
RN [1] {ECO:0000313|EMBL:KFQ54042.1, ECO:0000313|Proteomes:UP000053840}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N333 {ECO:0000313|EMBL:KFQ54042.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family.
CC {ECO:0000256|ARBA:ARBA00007025}.
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DR EMBL; KK945562; KFQ54042.1; -; Genomic_DNA.
DR Proteomes; UP000053840; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd18668; CD1_tandem_CHD5-9_like; 1.
DR CDD; cd18663; CD2_tandem_CHD5-9_like; 1.
DR CDD; cd18059; DEXHc_CHD7; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 2.40.50.40; -; 2.
DR Gene3D; 3.40.5.120; -; 2.
DR Gene3D; 1.10.10.60; Homeodomain-like; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR InterPro; IPR006576; BRK_domain.
DR InterPro; IPR037259; BRK_sf.
DR InterPro; IPR016197; Chromo-like_dom_sf.
DR InterPro; IPR000953; Chromo/chromo_shadow_dom.
DR InterPro; IPR023780; Chromo_domain.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR PANTHER; PTHR46850; CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 9; 1.
DR PANTHER; PTHR46850:SF3; DNA HELICASE; 1.
DR Pfam; PF07533; BRK; 2.
DR Pfam; PF00385; Chromo; 2.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR SMART; SM00592; BRK; 2.
DR SMART; SM00298; CHROMO; 2.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF160481; BRK domain-like; 2.
DR SUPFAM; SSF54160; Chromo domain-like; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50013; CHROMO_2; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000313|EMBL:KFQ54042.1};
KW Helicase {ECO:0000313|EMBL:KFQ54042.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053840};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 101..168
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT DOMAIN 183..248
FT /note="Chromo"
FT /evidence="ECO:0000259|PROSITE:PS50013"
FT DOMAIN 281..455
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 595..765
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 1..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..260
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 877..902
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1137..1199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1444..1583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2121..2196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2242..2307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..66
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 81..96
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 877..900
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1153..1192
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1444..1465
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1466..1536
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1554..1572
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2136..2160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2161..2196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2246..2280
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2283..2307
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ54042.1"
FT NON_TER 2307
FT /evidence="ECO:0000313|EMBL:KFQ54042.1"
SQ SEQUENCE 2307 AA; 260875 MW; 322BD1EB81CF17FA CRC64;
SNKKPDSETS AAKKKGNKGK EGSENSDLEK TPPPSPHPED EDDPGVQKRR SSRQVKRKRY
TEDLEFKISD EEADDADAAG RDSPSNTSQS EQQESADAEG PVVEKIMSSR SVKKKMENGE
EVEVEEFYVK YKNFSYLHCQ WASVEELDKD KRIQQKIKRF KAKQGQNKFL SEIDDELFNP
DYVEVDRILD FSRSTDDNGE PVTHYLVKWC SLPYEDSTWE LKQDIDQAKI EEFEKLMSRE
PEMERVERPP ADDWKKSESS REYKNNNKLR EYQLEGVNWL LFNWYNTRNC ILADEMGLGK
TIQSITFLYE IYLKGIHGPF LVIAPLSTIP NWEREFRTWT ELNVVVYHGS QASRRTIQLY
EMYFKDPQGR VIKGSYKFHA IITTFEMILT DCPELRNIPW RCVVIDEAHR LKNRNCKLLE
GLKMMDLEHK VLLTGTPLQN TVEELFSLLH FLEPGRFPSE TTFMQEFGDL KTEEQVQKLQ
AILKPMMLRR LKEDVEKNLA PKEETIIEVE LTNIQKKYYR AILEKNFTFL SKGGGQANVP
NLLNTMMELR KCCNHPYLIN GAEEKILEEF KETHNADSPD FQLQAMIQAA GKLVLIDKLL
PKLKAGGHRV LIFSQMVRCL DILEDYLIQR RYPYERIDGR VRGNLRQAAI DRFSRPDSDR
FVFLLCTRAG GLGINLTAAD TCIIFDSDWN PQNDLQAQAR CHRIGQSKSV KIYRLITRNS
YEREMFDKAS LKLGLDKAVL QSMSGRENAT NGVQQLSKKE IEDLLRKGAY GALMDEEDEG
SKFCEEDIDQ ILLRRTHTIT IESEGKGSTF AKASFVASGN RTDISLDDPN FWQKWAKKAE
LDIDALNGRN NLVIDTPRVR KQTRLYSAVK EDELMEFSDL ESDSEEKPST KPRRPQDKSQ
GYARSECFRV EKNLLVYGWG RWTDILSHGR YKRQLTEQDV ETICRTILVY CLNHYKGDEN
IKSFIWDLIT PTADGQTRAL VNHSGLSAPV PRGRKGKKVK AQSSQPMLQD ADWLTTCNPD
VLFQEDSYRK HLKHHCNKVL LRVRMLYYLR QEVIGDQADK ILEGADSSEI DVWIPEPFHA
EVPADWWDKE ADKSLLIGVF KHGYEKYNSM RADPALCFLE RVGMPDAKAI AAEQRGTDML
ADGGDGGEFD REDEDPEYKP TRTPFKDEID EFANSPPEDK EESVEIHPNK HGESNSELGQ
LYWPNTSTLT TRLRRLITAY QRSYKRQQMR QEALMKTDRR RRRPREEVRA LEAEREAIIT
EKRQKWTRRE EADFYRVVST FGIIFDPVKH QFDWNQFRAF ARLDKKSDES LEKYFNGFVN
MCRRVCRMPV KPDDEPPDLS TMIEERASRT LYRIELLRKI REQVLHHPQL GERLKLCQPS
LDLPEWWECG KHDKDLLIGA AKHGVSRTDY HILNDPELSF LEAHKNFAQN RGTGNANTVS
SVNPLGAGCS QTPPIVPSTP IQEEKITEQT ESKVEGSENP AAKEKSDIKE ETDTADKDTK
PDCDAEAEPG SVKCELKDIE MNTDVDPKSI SEKGSEEDEE EKMDDDDKSE ESSQPEAGAV
SQGKNFDEES NASMSTARDE TRDGFYMEDG DASVVQLLHE RTFAFSFWPK DRVMINRLDN
ICEAVLKGKW PVNRRQMFDF QGLIPGYTPT AVDSPLQKRS FAELSMVGQA SASGSEDITV
SPQLSKEDAL NLSVPRQRRR RRRKIEIEAE RAAKRRNLME MVAQLRESQV VSENGQEKVV
DLSKASREAA SSTSNFSSVT SKFILPNVST PVSDAFKTQM ELLQAGLSRT PTRHLLNGSL
IDGEPPMKRR RGRRKNVEGL DLLFMSNKRT SLTVEDAEVT KAFEEDMEAL PARNIPSPGQ
LDPDTRIPVI NLEDGTRLVG EDAPKNKDLV EWLKLHPTYT VDMPSYVPKS ADVLFSPFQK
PKQKRHRCRN PNKLDINTLT GEERVPVVNK RNGKKMGGAM APPMKDLPRW LEENPEFAVA
PDWTDIVKQS GFVPESMFDR LLTGPVVREE GASRRGRRPK SEIAKAAAAA AAVASTSGIN
PLLMNSLFAG MDLTSLQNLQ NLQSLQLAGL MGFPPGLATA AAAGGDAKNP AAMLPLMLPG
MAGLPNMFGL SGLLNNPITA TTGNATTASG QGETEDGASK AEEKKNENEE ENKDSEKSTD
TVSATDSANG SVSAATAATT ATATTTTTTN TGLPTNPLAF NPFLLSTMAP GLFYPSMFLP
PGLGGLTLPG FPALAGLQNA VGSNEEKATD KTEGTAFKDE ENLEGSDAEE SLDKTADSSV
LEDEIAQGEE LDSLDGGEEI ENNENDE
//
