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Database: UniProt
Entry: A0A091T7L7_PHALP
LinkDB: A0A091T7L7_PHALP
Original site: A0A091T7L7_PHALP 
ID   A0A091T7L7_PHALP        Unreviewed;       505 AA.
AC   A0A091T7L7;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   10-MAY-2017, entry version 19.
DE   RecName: Full=Sodium channel protein {ECO:0000256|RuleBase:RU361132};
DE   Flags: Fragment;
GN   ORFNames=N335_04628 {ECO:0000313|EMBL:KFQ70376.1};
OS   Phaethon lepturus (White-tailed tropicbird).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Pelecaniformes; Phaethontidae;
OC   Phaethon.
OX   NCBI_TaxID=97097 {ECO:0000313|EMBL:KFQ70376.1, ECO:0000313|Proteomes:UP000053638};
RN   [1] {ECO:0000313|EMBL:KFQ70376.1, ECO:0000313|Proteomes:UP000053638}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N335 {ECO:0000313|EMBL:KFQ70376.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates the voltage-dependent sodium ion permeability
CC       of excitable membranes. {ECO:0000256|RuleBase:RU361132}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU361132}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- SIMILARITY: Belongs to the sodium channel (TC 1.A.1.10) family.
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU361132}.
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DR   EMBL; KK441658; KFQ70376.1; -; Genomic_DNA.
DR   PhylomeDB; A0A091T7L7; -.
DR   Proteomes; UP000053638; Unassembled WGS sequence.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   InterPro; IPR031649; GPHH_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR001696; Na_channel_asu.
DR   Pfam; PF16905; GPHH; 1.
DR   Pfam; PF00520; Ion_trans; 2.
DR   PRINTS; PR00170; NACHANNEL.
DR   SMART; SM00015; IQ; 1.
DR   PROSITE; PS50096; IQ; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053638};
KW   Ion channel {ECO:0000256|RuleBase:RU361132,
KW   ECO:0000313|EMBL:KFQ70376.1};
KW   Ion transport {ECO:0000256|RuleBase:RU361132};
KW   Membrane {ECO:0000256|RuleBase:RU361132};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053638};
KW   Sodium {ECO:0000256|RuleBase:RU361132};
KW   Sodium channel {ECO:0000256|RuleBase:RU361132};
KW   Sodium transport {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361132};
KW   Transport {ECO:0000256|RuleBase:RU361132};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM      6     25       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM     83    101       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    113    131       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    138    163       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    200    228       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    304    327       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   DOMAIN        2     33       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN       82    337       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      341    397       GPHH. {ECO:0000259|Pfam:PF16905}.
FT   NON_TER     505    505       {ECO:0000313|EMBL:KFQ70376.1}.
SQ   SEQUENCE   505 AA;  57866 MW;  C3F12061AD8D047C CRC64;
     MYIYFVAFII FGSFFTLNLF IGVIIDNFNQ QKKKISQDIF MTEEQKKYYN AMKKLGSKKP
     QKPIPRPANK LQGLVFDIVT KQAFDITIMV LICLNMVTMM IETDDQGELM QNILYWINLV
     FVVLFTGECV LKLFSLRYYY FTIGWNIFDF VVVILSIVGM FLAEVIEKYF VSPTLFRVVR
     LARIGRILRL IKGAKGIRTL LFALMMSLPA LFNIGLLLFL VMFIYAIFGM SNFAYVKREA
     GIDDMFNFET FGNSMICLFQ ITTSAGWDGL LAPILNSGEP DCDPNKAHPG SSVKGDCGNP
     SVGIFFFVSY IIISFLVVVN MYIAVILENF SVATEESAEP LSEDDFEMFY EVWEKYDPDA
     TQFIEYSKLS DFAASLDPPL NIPKPNTIQL IAMDLPMVSG DRIHCLDILF AFTKRVLGES
     DEMDALRIQM EDRFMAANPS KVSYEPITTT LKRKQEELSA TIIQRAYRRY LLRQTVKKLS
     FMYQKDGVDL LIKKDMVIDK LSENS
//
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