ID A0A091TJW6_PHALP Unreviewed; 424 AA.
AC A0A091TJW6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Tumor necrosis factor receptor superfamily member 1A {ECO:0000313|EMBL:KFQ76579.1};
DE Flags: Fragment;
GN ORFNames=N335_02885 {ECO:0000313|EMBL:KFQ76579.1};
OS Phaethon lepturus (White-tailed tropicbird).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Eurypygimorphae; Phaethontiformes;
OC Phaethontidae; Phaethon.
OX NCBI_TaxID=97097 {ECO:0000313|EMBL:KFQ76579.1, ECO:0000313|Proteomes:UP000053638};
RN [1] {ECO:0000313|EMBL:KFQ76579.1, ECO:0000313|Proteomes:UP000053638}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N335 {ECO:0000313|EMBL:KFQ76579.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004251};
CC Single-pass type I membrane protein {ECO:0000256|ARBA:ARBA00004251}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
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DR EMBL; KK456315; KFQ76579.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091TJW6; -.
DR PhylomeDB; A0A091TJW6; -.
DR Proteomes; UP000053638; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd08313; Death_TNFR1; 1.
DR CDD; cd10576; TNFRSF1A; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 2.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR033994; TNFRSF1A_death.
DR InterPro; IPR033993; TNFRSF1A_N.
DR PANTHER; PTHR46861; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A; 1.
DR PANTHER; PTHR46861:SF1; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 1A; 1.
DR Pfam; PF00531; Death; 1.
DR Pfam; PF00020; TNFR_c6; 2.
DR SMART; SM00005; DEATH; 1.
DR SMART; SM00208; TNFR; 3.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF57586; TNF receptor-like; 2.
DR PROSITE; PS50017; DEATH_DOMAIN; 1.
DR PROSITE; PS00652; TNFR_NGFR_1; 1.
DR PROSITE; PS50050; TNFR_NGFR_2; 2.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00206}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KFQ76579.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053638};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..424
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001879767"
FT TRANSMEM 221..239
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 95..137
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 95..137
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 138..176
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 138..176
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 326..409
FT /note="Death"
FT /evidence="ECO:0000259|PROSITE:PS50017"
FT DISULFID 96..111
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 139..154
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ76579.1"
FT NON_TER 424
FT /evidence="ECO:0000313|EMBL:KFQ76579.1"
SQ SEQUENCE 424 AA; 47351 MW; 03534D5CE9D2B9D5 CRC64;
SLPLPRYLQV VLIFVCVLMK ESVEIAPVPY TLQVHRVALD GRDPSNPLKR EKRQVQCQLG
QYLHPRETHC CMRCHAGTYK AKDCDRPDQA PVCLPCANGT FTAVDNTMSK CFQCTHCRTE
FQQIVESPCT PKQDTICGCR KNQYQIGLSD LFQCRNCSLC GNGIIANCSK NRDTICRCKP
QFFLTLSNVC KPCNSCIGEE CLQCHSPVTT SPTSSGLNGS LVLGIIVAIF GVISVLYIVN
KVVKLAQKNG IASSFYSCVS LPQTTKEPVC EVEVKRSEIS ILLSESQKET QLSVNPTPPP
APLLQSSHEL PDCVRPARTT QLPGNPAILY TVVDHVPPSR WKEFVRRLGL SDYDLERTEM
EHRRLRDVQY EMLRLWKLQM GRAATVEHIS CVLNQMELSG CSEAIQEALL NQNSPQPCSL
HSHL
//
