ID   A0A091TL65_PHALP        Unreviewed;       887 AA.
AC   A0A091TL65;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   SubName: Full=Cullin-4B {ECO:0000313|EMBL:KFQ77299.1};
GN   ORFNames=N335_13473 {ECO:0000313|EMBL:KFQ77299.1};
OS   Phaethon lepturus (White-tailed tropicbird).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Eurypygimorphae; Phaethontiformes;
OC   Phaethontidae; Phaethon.
OX   NCBI_TaxID=97097 {ECO:0000313|EMBL:KFQ77299.1, ECO:0000313|Proteomes:UP000053638};
RN   [1] {ECO:0000313|EMBL:KFQ77299.1, ECO:0000313|Proteomes:UP000053638}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N335 {ECO:0000313|EMBL:KFQ77299.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KK457640; KFQ77299.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091TL65; -.
DR   PhylomeDB; A0A091TL65; -.
DR   UniPathway; UPA00143; -.
DR   Proteomes; UP000053638; Unassembled WGS sequence.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF66; CULLIN-4B; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Isopeptide bond {ECO:0000256|ARBA:ARBA00022499};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053638};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          532..760
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
FT   REGION          1..89
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        20..87
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   887 AA;  101917 MW;  A502FF1C1C7FE506 CRC64;
     MFPTGFSSPN PPAAAQEVRP ATDGNTSSSS SCKKRKLNNS SNSNSEREEF DSISSCASSP
     SKNTSSSSSS VITTSSCSSS GVASSNHHLQ KKLRFEDSVD FIGLDVKMAE ESSSSSSPAA
     SSQQQHQQQL KNKSLLISSV AVGHHANGLT KAASSTVSSF ANSKPGSAKK LVIKNFKDKP
     KLPENYTDET WQKLKEAVEA IQNSTSIKYN LEELYQAVEN LCSYKISANL YKQLRQICED
     HIKAQIHQFR EYPFFYVLFL KKIDKCWQDH CRQMIMIRSI FLFLDRTYVL QNSMLPSIWD
     MGLELFRTHI ISDQKVQNKT IDGILLLIER ERNGEAIDRS LLRSLLSMLS DLQIYQDSFE
     HRFLEETNRL YAAEGQRLMQ EREVPEYLHH VNKRLEEEAD RIITYLDQST QKPLIATVEK
     QLLGEHLTAI LQKGLNHLLD ENRIQDLSLL YQLFSRVRGG VQVLLQHWIE YIKAFGSTIV
     INPEKDKTMV QELLDFKDKV DHIIDVCFLK NEKFVNAMKE AFETFINKRP NKPAELIAKY
     VDSKLRAGNK EATDEELEKM LDKIMIIFRF IYGKDVFEAF YKKDLAKRLL VGKSASVDAE
     KSMLSKLKHE CGAAFTSKLE GMFKDMELSK DIMIQFKQYM QNQNVPGNIE LTVNILTMGY
     WPTYVPMEVH LPPEMVKLQE IFKTFYLGKH SGRKLQWQST LGHCVLKAEF KEGRKELQVS
     LFQTLVLLMF NEGEEFSLEE IKQATGIEDG ELRRTLQSLA CGKARVLTKS PKGKDVEDGD
     KFTCNDDFRH KLFRIKINQI QMKETVEEQA STTERVFQDR QYQIDAAIVR IMKMRKTLSH
     NLLVSEVYNQ LKFPVKPADL KKRIESLIDR DYMERDKENP NQYNYIA
//