ID   A0A091TYM0_PHALP        Unreviewed;       955 AA.
AC   A0A091TYM0;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=Pleckstrin homology domain-containing family M member 2 {ECO:0000313|EMBL:KFQ83321.1};
DE   Flags: Fragment;
GN   ORFNames=N335_10134 {ECO:0000313|EMBL:KFQ83321.1};
OS   Phaethon lepturus (White-tailed tropicbird).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Eurypygimorphae; Phaethontiformes;
OC   Phaethontidae; Phaethon.
OX   NCBI_TaxID=97097 {ECO:0000313|EMBL:KFQ83321.1, ECO:0000313|Proteomes:UP000053638};
RN   [1] {ECO:0000313|EMBL:KFQ83321.1, ECO:0000313|Proteomes:UP000053638}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N335 {ECO:0000313|EMBL:KFQ83321.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KK468610; KFQ83321.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091TYM0; -.
DR   PhylomeDB; A0A091TYM0; -.
DR   Proteomes; UP000053638; Unassembled WGS sequence.
DR   GO; GO:0005764; C:lysosome; IEA:UniProtKB-KW.
DR   CDD; cd13309; PH_SKIP; 1.
DR   CDD; cd17680; RUN_PLEKHM2; 1.
DR   Gene3D; 1.20.58.900; -; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR004012; Run_dom.
DR   InterPro; IPR037213; Run_dom_sf.
DR   InterPro; IPR047327; RUN_PLEKHM2.
DR   PANTHER; PTHR46556; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2; 1.
DR   PANTHER; PTHR46556:SF1; PLECKSTRIN HOMOLOGY DOMAIN-CONTAINING FAMILY M MEMBER 2; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF02759; RUN; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00593; RUN; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF140741; RUN domain-like; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50826; RUN; 1.
PE   4: Predicted;
KW   Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053638}.
FT   DOMAIN          44..166
FT                   /note="RUN"
FT                   /evidence="ECO:0000259|PROSITE:PS50826"
FT   DOMAIN          748..850
FT                   /note="PH"
FT                   /evidence="ECO:0000259|PROSITE:PS50003"
FT   REGION          218..562
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        225..298
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        328..342
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        428..446
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        487..501
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        511..561
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFQ83321.1"
FT   NON_TER         955
FT                   /evidence="ECO:0000313|EMBL:KFQ83321.1"
SQ   SEQUENCE   955 AA;  105085 MW;  D15BE935FEF89C5E CRC64;
     KKKRGNASIC SSLSLPSLGA SLSRGIPPLQ SYFAACEDET PAIRNHDKVL QRLCEHLDHA
     LLYGLQDLSS GYWVLVVHFT RREAVKQIEV LQHVATNLGR SRAWLYLALN ENSLESYLRL
     FQENLSLLHK YYVKNALVCS HDHLTLFLTL VSGLEFIRFD LDLDAPYLDL APYMPDYYKP
     QYLLDFEARL PSSVHGSDSL SLNSFNSVTS TNLEWDDSAI APSSEDGDLT DTLSCPRSTA
     SEANGSKASV KSPTQRYNPF NEEKADAPSS TETTPVHTAS QEKAEATPEG TDQSESCTEL
     EVIRLAKKKK TGKKKKAKPE EPVNTPAPVV PETQQASGDS GVNGLSDREE PQKDDGPAVP
     AGEPSPGGQQ EGRERSALSQ LALRIPEMKD TSMESVGQPL SKVMDRLNGQ LDPGGWNAPL
     EPPGQSFRTG TPGETPDGSS SGDFSEGISA PMDFYRFTVE SPNAAAPGGG HHDAPGPGQP
     PHVPGSPEAP EEEESREGEA VGAVEESGGA SDEPQTRQTE TTNPQALHEP KKEQPSPSPS
     SAEDSGVEEG QGSPSELTHP SEFRVDNNHL LLLMIHVFRE NEEQLFRMIR MSTGHMEGNL
     QLIYVLLTDC YVYLIRKGAA EKPYMVEEAV SYNELDYISV GLDQQTVTLV CTNRRKQFLL
     DTADVALTEF FLVSLKSAMI KGCREPPYPS ILTDATMEKL ALAKFVAQES KCEACDVVVR
     FYGLVHWEDP MDEALGPSNN SYTSTENAVT KDGILHYKAG TSYLGKEQWK TCFVVLSNGI
     LYQYPDRTDV TPLLSINMGG EQCGGCRRSN TTDRPHSFQV ILTDRPSLEL SAENEEDMAD
     WMQYFCQAVS KGVIPQGVAP TPCVPCCLVL TDEKAFTCHE DCQTSFFRSL GTVELTDVTA
     VSTEAGKEYC ILEFAQDRKQ FLPPWVLYFS CTTELERFLS ALNAAWRNIY QVSVQ
//