ID A0A091UPQ4_NIPNI Unreviewed; 768 AA.
AC A0A091UPQ4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Microprocessor complex subunit DGCR8 {ECO:0000313|EMBL:KFQ91885.1};
GN ORFNames=Y956_05975 {ECO:0000313|EMBL:KFQ91885.1};
OS Nipponia nippon (Crested ibis) (Ibis nippon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae;
OC Nipponia.
OX NCBI_TaxID=128390 {ECO:0000313|EMBL:KFQ91885.1, ECO:0000313|Proteomes:UP000053283};
RN [1] {ECO:0000313|EMBL:KFQ91885.1, ECO:0000313|Proteomes:UP000053283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFQ91885.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL409758; KFQ91885.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091UPQ4; -.
DR STRING; 128390.A0A091UPQ4; -.
DR eggNOG; KOG4334; Eukaryota.
DR Proteomes; UP000053283; Unassembled WGS sequence.
DR GO; GO:0070877; C:microprocessor complex; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0042802; F:identical protein binding; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0031053; P:primary miRNA processing; IEA:InterPro.
DR CDD; cd19867; DSRM_DGCR8_rpt1; 1.
DR CDD; cd19868; DSRM_DGCR8_rpt2; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 3.30.160.20; -; 2.
DR Gene3D; 3.30.160.590; -; 1.
DR InterPro; IPR040375; DGCR8.
DR InterPro; IPR014720; dsRBD_dom.
DR PANTHER; PTHR13482:SF3; MICROPROCESSOR COMPLEX SUBUNIT DGCR8; 1.
DR PANTHER; PTHR13482; MICRORNA PROCESSOR COMPLEX SUBUNIT DGCR8; 1.
DR Pfam; PF00035; dsrm; 2.
DR SMART; SM00358; DSRM; 2.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 2.
DR PROSITE; PS50137; DS_RBD; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053283};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT DOMAIN 506..573
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 259..284
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 356..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 24..42
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 259..275
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 768 AA; 86454 MW; 444CA225FF801F1C CRC64;
MEKYENVPPL PKEPAREMNV ENHTCPPPLP PNEQPPPPPL QTSSDAEVMD VGSGGDGQSD
TPAGDTHSIC RTQLLTKGSA CYKSRLIIDP NSSDQSPRTA RHAPSVRKFT PDLKLLKDVK
ISVSFTESCK SKDRKVLYTG VEQDYKADTD FGINNVNGDL HVCPFGGSNG KAVGIGGEND
DKKDDENDID QEKRVEYAVL DELEDFTDNL MEIDEEGGGF TSKAIVQRDK VDEETLNYSY
EDDFDNDVDA LLEEGLRAPK TRRLENEKYG GESDHQSDGE TSVQPMMTKI KTVLKSRGRP
PTEPLPDGWI MTFHNSGESR VVTWSRPYFL GTGSIRKHDP PLSSIPCLHY KKMKENEERE
QNNDITPNGE VSPVKHLDKS SELDCQTEEP DSTAADSGPL DEKDPSGGDA AQGALGQVKA
KVEVCKDESV DLEDFRRYLE KRFDFEQVTV KKFRTWAERR QFNREMKRKQ AESERPILPA
NQKLITLSVQ DAPTKKEFVI NPNGKSEVCI LHEYMQRVLK VRPVYNFFEC ENPSEPFGAS
VIIDGVTYGA GTASSKKLAK NKAARATLEI LIPDFVKQTS EEKPKDSEEL EYFNHISIED
SRVYELTSKA GLLSPYQILH ECLKRNHGMG DTSIKFEVIP GKNQKSEYVM TCGKHTVRGW
CKNKRVGKQL ASQKILQLLH PHVKNWGSLL RMYGRESSKM VKQETSDKSV IELQQYAKKN
KPNLHILNKL QEEMKKLAQE REETRKKPKM TIVESAQPGS EPLCTVDV
//
