ID A0A091USH3_NIPNI Unreviewed; 854 AA.
AC A0A091USH3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 {ECO:0000313|EMBL:KFQ93666.1};
DE Flags: Fragment;
GN ORFNames=Y956_00359 {ECO:0000313|EMBL:KFQ93666.1};
OS Nipponia nippon (Crested ibis) (Ibis nippon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae;
OC Nipponia.
OX NCBI_TaxID=128390 {ECO:0000313|EMBL:KFQ93666.1, ECO:0000313|Proteomes:UP000053283};
RN [1] {ECO:0000313|EMBL:KFQ93666.1, ECO:0000313|Proteomes:UP000053283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFQ93666.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
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DR EMBL; KL410062; KFQ93666.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091USH3; -.
DR STRING; 128390.A0A091USH3; -.
DR eggNOG; KOG2645; Eukaryota.
DR Proteomes; UP000053283; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd16018; Enpp; 1.
DR CDD; cd00091; NUC; 1.
DR Gene3D; 4.10.410.20; -; 2.
DR Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR Gene3D; 3.40.570.10; Extracellular Endonuclease, subunit A; 1.
DR InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR InterPro; IPR001604; DNA/RNA_non-sp_Endonuclease.
DR InterPro; IPR044929; DNA/RNA_non-sp_Endonuclease_sf.
DR InterPro; IPR020821; Extracellular_endonuc_su_A.
DR InterPro; IPR044925; His-Me_finger_sf.
DR InterPro; IPR002591; Phosphodiest/P_Trfase.
DR InterPro; IPR036024; Somatomedin_B-like_dom_sf.
DR InterPro; IPR001212; Somatomedin_B_dom.
DR PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1.
DR PANTHER; PTHR10151:SF77; ECTONUCLEOTIDE PYROPHOSPHATASE_PHOSPHODIESTERASE FAMILY MEMBER 1; 1.
DR Pfam; PF01223; Endonuclease_NS; 1.
DR Pfam; PF01663; Phosphodiest; 1.
DR Pfam; PF01033; Somatomedin_B; 2.
DR SMART; SM00892; Endonuclease_NS; 1.
DR SMART; SM00477; NUC; 1.
DR SMART; SM00201; SO; 2.
DR SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
DR SUPFAM; SSF54060; His-Me finger endonucleases; 1.
DR SUPFAM; SSF90188; Somatomedin B domain; 2.
DR PROSITE; PS00524; SMB_1; 2.
DR PROSITE; PS50958; SMB_2; 2.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053283};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..854
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001880984"
FT DOMAIN 24..64
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT DOMAIN 65..109
FT /note="SMB"
FT /evidence="ECO:0000259|PROSITE:PS50958"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ93666.1"
FT NON_TER 854
FT /evidence="ECO:0000313|EMBL:KFQ93666.1"
SQ SEQUENCE 854 AA; 98143 MW; 0453EAFA9FF6A343 CRC64;
VLCVCMLTTI LGCIFGLKPS CSKDVKTCKG RCFERTFGSC RCDRDCVKLG NCCLDYQETC
IQPAHIWICN KFRCGEKRRP EYHCSCSDDC VENKDCCVNY YAVCKGEASW VEEECEDITE
PQCPKGFTKS PVLLFSLDGF RAEYLQTWGG LLPVISKLQK CGTYTSSLRP VYPSKTFPNH
YSIVTGLYPE SHGIIDNKMY DPKRNASFTL KSEEKFNPQW YQGQPIWLTA MYQGLKAATF
FWPGSDVAVN GTFPNLYEKY NSSIPFEERV VTVLRWLQLP EDERPHFYTL YLEEPDSSGH
KFGPVSSGVI MALQRVDNIV GMLMDGLKQM NLHKCLNIIF ISDHGMEAGS CRKTAYLNTY
LDNVQDFIVV PGPAARLRPN NVPDEYFSFN YEGIVRNLTC MEPNQPFKAY MKQLLPKRFH
YSYNDRIEPL HFYLDSQWQL ARKPLEIKSC TGGFHGSDNR FPSMQAMFIG FGPGFKFRNQ
VDPFENIEVY NLMCDLLDLK PAPNNGTHGR LNHLLRNPVY TPHHPKEASH PSECPVVGQK
AFSVSLGCSC RTEGLPIRDF HQRLNLTETE VKKTEKLTLP YGRPRVLQKR HNYCLLYHYR
YVSGYSKDYR MSLWSAYTVN KDDKWVSATE DTSSCLHKDV RISFNHNQTC LFYNNHPRLT
YGFLSPPNFM TDAKKPHYDA LLTSNIVPMY PAFKVLWSYF HQSLLPEYAA ARNGVNVVSG
PVFDYDSDGL YDTPEKVKRY RNLLCFRHPS NSEVPVPTHF FIVLTSCKNT SETPVECEGS
LDALSFIVPH REDNSESCAD GKSESLWVEE RMKFHTARIR DIELLTGLSF YQDRKQPVSE
ILQLKTYLPT FEVV
//
