ID A0A091UWE8_NIPNI Unreviewed; 832 AA.
AC A0A091UWE8;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Very low-density lipoprotein receptor {ECO:0000313|EMBL:KFQ94767.1};
DE Flags: Fragment;
GN ORFNames=Y956_16449 {ECO:0000313|EMBL:KFQ94767.1};
OS Nipponia nippon (Crested ibis) (Ibis nippon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae;
OC Nipponia.
OX NCBI_TaxID=128390 {ECO:0000313|EMBL:KFQ94767.1, ECO:0000313|Proteomes:UP000053283};
RN [1] {ECO:0000313|EMBL:KFQ94767.1, ECO:0000313|Proteomes:UP000053283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFQ94767.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; KL410236; KFQ94767.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A091UWE8; -.
DR STRING; 128390.A0A091UWE8; -.
DR eggNOG; KOG1215; Eukaryota.
DR Proteomes; UP000053283; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00112; LDLa; 8.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 8.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR24270; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED; 1.
DR PANTHER; PTHR24270:SF8; VERY LOW-DENSITY LIPOPROTEIN RECEPTOR; 1.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF14670; FXa_inhibition; 2.
DR Pfam; PF00057; Ldl_recept_a; 8.
DR Pfam; PF00058; Ldl_recept_b; 5.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00181; EGF; 5.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00192; LDLa; 8.
DR SMART; SM00135; LY; 5.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR SUPFAM; SSF57424; LDL receptor-like module; 8.
DR SUPFAM; SSF63825; YWTD domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 2.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS01209; LDLRA_1; 5.
DR PROSITE; PS50068; LDLRA_2; 8.
DR PROSITE; PS51120; LDLRB; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Lipoprotein {ECO:0000313|EMBL:KFQ94767.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:KFQ94767.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000053283};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 777..798
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 329..368
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 374..409
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REPEAT 459..504
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 505..547
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 548..591
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 592..634
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DISULFID 6..18
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 13..31
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 25..40
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 45..57
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 52..70
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 107..122
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 127..139
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 134..152
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 146..161
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 166..178
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 173..191
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 212..224
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 219..237
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 231..246
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 251..263
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 258..276
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 270..285
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 299..317
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 378..388
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFQ94767.1"
FT NON_TER 832
FT /evidence="ECO:0000313|EMBL:KFQ94767.1"
SQ SEQUENCE 832 AA; 91510 MW; A8A2CADCC000ACFA CRC64;
GARAKCEESQ FPCSNGRCIP LLWKCDGDED CSDGSDESAC VKKTCGESDF VCISGQCVPN
RWQCDGDPDC EDGSDESAEL CHMRTCRVNE ISCGPQSTQC IPVSWKCDGE KDCDSGEDEE
NCGNVTCSPA EFTCSSGQCI SKSFVCNGQD DCSDGSDELE CAPPTCGVHE FQCKSSTCIP
ISWVCDDDAD CSDHSDESLE QCGRQPAPPV KCSASEVQCG SGECIHKKWR CDGDPDCKDG
SDEINCPSRT CRPDQFRCED GNCIHGSRQC NGVRDCLDGT DEANCNNVIQ CSGPGKFKCR
SGECIDANKV CNQQKDCKDW SDEPLKECNV NECLVNNGGC SHICRDLVIG YECDCPAGFE
LIDRRTCGGK YQVDIDECQN PGICSQICIN LKGGYKCECS RGYQMDLATG VCKAVGKEPC
LIFTNRRDIR KIGLERKEYI QLVEQLRNTV ALDADIAEQK LYWADFSQKA IFSASVDTRD
KVGTHVRILD NVHSPAGIAV DWIYKNIYWS DSTAKTISVA SLDGTKRKVL FLSELREPAS
IAVDPLSGFM YWSDWGEPAK IEKAGMNGFD RQQLVTTEIQ WPNGIALDLV KSRLYWLDSK
LHMLSSVDLN GQDRRVVLKS HMFLPHPLAL TIFEDRVYWI DGENEAVYGA NKFTGSELVT
LVNNLNDAQD IIVYHELVQP SGRNWCEENM ANGGCSYLCL PAPQINEHSP KYTCACPVGY
FLQEDGLRCA GTGTTVAYTE AKDTSTREKS PTVGLVPGGF NISGTTSEVA AAGGTSAAWT
VLPVLLLVMA AVAGYFMWRN WQHKNMKSMN FDNPVYLKTT EEDLTIDVGR HS
//
