ID A0A091VDM3_NIPNI Unreviewed; 315 AA.
AC A0A091VDM3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Zinc transporter ZIP3 {ECO:0000256|ARBA:ARBA00039395};
DE AltName: Full=Solute carrier family 39 member 3 {ECO:0000256|ARBA:ARBA00042778};
DE AltName: Full=Zrt- and Irt-like protein 3 {ECO:0000256|ARBA:ARBA00041702};
GN ORFNames=Y956_07013 {ECO:0000313|EMBL:KFR01447.1};
OS Nipponia nippon (Crested ibis) (Ibis nippon).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Pelecaniformes; Threskiornithidae;
OC Nipponia.
OX NCBI_TaxID=128390 {ECO:0000313|EMBL:KFR01447.1, ECO:0000313|Proteomes:UP000053283};
RN [1] {ECO:0000313|EMBL:KFR01447.1, ECO:0000313|Proteomes:UP000053283}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_Y956 {ECO:0000313|EMBL:KFR01447.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Zn(2+)(in) = Zn(2+)(out); Xref=Rhea:RHEA:29351,
CC ChEBI:CHEBI:29105; Evidence={ECO:0000256|ARBA:ARBA00036307};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:29352;
CC Evidence={ECO:0000256|ARBA:ARBA00036307};
CC -!- SUBCELLULAR LOCATION: Apical cell membrane
CC {ECO:0000256|ARBA:ARBA00004424}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004424}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000256|ARBA:ARBA00006939}.
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DR EMBL; KL410953; KFR01447.1; -; Genomic_DNA.
DR RefSeq; XP_009467364.1; XM_009469089.1.
DR AlphaFoldDB; A0A091VDM3; -.
DR STRING; 128390.A0A091VDM3; -.
DR GeneID; 104016249; -.
DR KEGG; nni:104016249; -.
DR CTD; 29985; -.
DR eggNOG; KOG1558; Eukaryota.
DR OrthoDB; 5482951at2759; -.
DR Proteomes; UP000053283; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006829; P:zinc ion transport; IEA:UniProt.
DR InterPro; IPR003689; ZIP.
DR PANTHER; PTHR11040:SF214; ZINC TRANSPORTER ZIP3; 1.
DR PANTHER; PTHR11040; ZINC/IRON TRANSPORTER; 1.
DR Pfam; PF02535; Zip; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053283};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..63
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 83..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 171..192
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 230..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..313
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 315 AA; 34005 MW; D680C52EA3B036AA CRC64;
MKIVVAKVLC LLGICVLMLA GSLLPVKIIE ADYEKAHRSK KVLALCNSFG GGVFLATCFN
ALLPAVREKL DVVLKQGNVT TDYPVAETIM MVGFFVTVFV EQLILTFQKE KPSFIDLETF
NAGSDVGSDS EYESPFIASS RGRTLYGEHG HRSHSHGLNI QELSRSSPLR LIGLVFALCT
HSIFEGLALG LQEEGGKVMS LFLGVAIHET LVAVALGISM AKSSLPLKDA VKMAVTVSLM
IPLGISIGMG IESTQNAASN ITSLLLQGIA GGTFLFITFF EILAKELEDK NDRLLKVLFL
VLGYTALAGL VFFKW
//
