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Database: UniProt
Entry: A0A091VW56_OPIHO
LinkDB: A0A091VW56_OPIHO
Original site: A0A091VW56_OPIHO 
ID   A0A091VW56_OPIHO        Unreviewed;      4847 AA.
AC   A0A091VW56;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   20-DEC-2017, entry version 20.
DE   SubName: Full=Ryanodine receptor 3 {ECO:0000313|EMBL:KFR07015.1};
GN   ORFNames=N306_10800 {ECO:0000313|EMBL:KFR07015.1};
OS   Opisthocomus hoazin (Hoatzin) (Phasianus hoazin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Opisthocomiformes; Opisthocomidae;
OC   Opisthocomus.
OX   NCBI_TaxID=30419 {ECO:0000313|EMBL:KFR07015.1, ECO:0000313|Proteomes:UP000053605};
RN   [1] {ECO:0000313|EMBL:KFR07015.1, ECO:0000313|Proteomes:UP000053605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N306 {ECO:0000313|EMBL:KFR07015.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
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DR   EMBL; KK734355; KFR07015.1; -; Genomic_DNA.
DR   PhylomeDB; A0A091VW56; -.
DR   Proteomes; UP000053605; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   Gene3D; 1.25.10.10; -; 2.
DR   Gene3D; 1.25.10.30; -; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR035910; IP3R_RIH_dom_sf.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF48371; SSF48371; 15.
DR   SUPFAM; SSF49899; SSF49899; 3.
DR   SUPFAM; SSF82109; SSF82109; 1.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50222; EF_HAND_2; 1.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000053605};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:KFR07015.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053605};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4160   4184       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4386   4406       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4450   4472       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4648   4669       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4728   4751       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      100    155       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      162    207       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      215    269       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      275    332       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      343    400       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      585    796       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1012   1208       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1254   1468       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     3921   3949       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   COILED      459    479       {ECO:0000256|SAM:Coils}.
FT   COILED     3220   3240       {ECO:0000256|SAM:Coils}.
FT   COILED     3574   3608       {ECO:0000256|SAM:Coils}.
FT   COILED     4301   4327       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   4847 AA;  550451 MW;  E146D8997846688F CRC64;
     MAEGGEGGED EIQFLRTDDE VVLQCVASIH KEQRKFCLAA EGLGNRLCFL EPTSEAKYVP
     PDLCICNFVL EQSLSVRALQ EMLTNTGDNA SEGAAQGGGH RTLLYGHAVL LRHSFSEMYL
     TCLTSSRSQT DKLAFDVGLR ENAAGEACWW TIHPASKQRS EGEKVRIGDD LILVSVSSER
     YLHLSMSNGS IQVDASFMQT LWNVHPTCSG SNIAEGYLLG GHVVRFFHGH DECLTIPSTD
     QNDSQHKKVL YETGGAGVRA RSLWRVEPLR ISWSGSNIRW GQPFRLRHIT TGRYLALNED
     EGLAMLDREK SDTTSTAFCF RASKELKEKQ DSSLKRDIDG MGVPEIKYGD SICFVQHVAS
     ALWLTYKAQD AKSARLGPLK RKVILHQEGH MDDGLTLQRC QNEESQAARI IRNTTSLFSQ
     FISGNNRTLS LTVLPVEEMA QTLQDLITYF QLPEEDLEHE DKQSKLRSLK NRQNLFKEEG
     MLALVLNCID RLNDYNSAAH FAGISREEHG TAWKQILNLL YKLLAALIRG NRNNCTQFSS
     NLDWLISKLD RLESSSGILE VLHCILIESP EALNIIAEDH IKSIISLLDK HGRNYKVLDV
     LCSLCVCNGV AVRANQNLIC DNLLPRRDLL LQTRLINDVT SIRPNIFLGV AEGSAQYKKW
     YFELIIDQVD PFLTAEPTHL RVGWASTSGY APYPGGGEGW GGNGVGDDLY SYGFDGLHLW
     SGRVSRAVAS VNQHLLASDD VVSCCLDLGV PSISFRINGQ PVQGMFENFG TEGFFFPVVS
     LSAGVKVRFL LGGRHGEFKF LPPAGYAPCY EALLPKEKMK LEPVKEYKRD SDGVRDLLGT
     TQFLSQASFI PCPIDTTQIA LPFHLEKIRD KLAENIHELW GMNKIELGWT YGKIRDDNKR
     HHPCLVEFSK LPETEKNYNL QMSTETLKTL LALGCHIVHA HPAAEEDLKK VKLPKNYMMS
     NGYKPAPLDL SEVKLLPSQE FLVDRLAENA HNVWAKDRIK QGWTYGIQQD LKNKRNPRLV
     PYALLDERTK KSNRDSLREA VRTFAGYGYN IEPPDQEIAD QTVEKVSIDK IRFFRVEQSY
     AVKSGKWYFE FEAVTGGDMR VGWARPGCRP DVELGADDQA FVFEGSKGQR WHQGSGFFGR
     SWQPGDVVGC MINLDDKSII FTLNGELLIT SKGSELAFAD FGIESGFVPI CALGLSQIGR
     MNLGMDASTF KYYTMCGLQE GFEPFAVNMN RDVAMWFSKR LPTFVNVPKN HPHVEIWRID
     GTIESPPRLK VTHKTFGTQN SNSDMIYCRL SMPIEFRSSF SFGMGVENAS SDAFQKRKHS
     QEIAAPSTTY FYSLRIFAGQ DASSVWVGWV TPDYHFYSEN FDLNKNCTVT VTLGDERGRV
     HESVKRSNCY MVWGGDVIAN SQRSGRSNVD LEIGCFVDLA TGMLSFTANG KELGTCYQVE
     PNTKLFPATF VQPTSTNLIQ FELGKLKNTM PLSAAIFKSE ERNPVPQCPP RLDVQTITPV
     LWSRMPNSFL KVETERVSER HGWVVQCLEP LQMMALHIPE ENRCVDILEL CEQEDLMKFH
     YHTLKLYSSV SALGNTRVAY ALCSHVDVSQ LFYTIDNRYL PGLLRSGFYD LLISIHLEHA
     KQAKLMMNNE FIIPVTDETR TIKLYPDETK KHGLPGVGLS TCLKPGFNFS TPCFIVTSEE
     RQTSSPEIPL DILKSKAISM LTEAVQCSGT HIRDPVGGQV AFQFVPVLKL IATLLIMGVF
     DDDNVKQVLL LIDPNVFGDH KEETEERTEK EEVTQVEEKA VEAGEKAIRE TKAPAKGLLQ
     TRLPESVKLQ MCHLLNYFCD CELQHRVEAI VSFADCYVSK LQYNQKYRYN ELMQALNMSA
     ALTAKKTKEF RSPPQEQINM LLNFQLGEDC PCPEEIRDEL YEFHDDLLIH CGIPLEEEEE
     EEEDSSLTGK LRSLMYKIKG PPKAEKVEPK EEEEKSPTTL KELISQTMVR WSQEDQIQDP
     ELVRIMYTLL RRQYDSIGEL LQALRKAYTI SAASVKDTIN LLAALGQIRS LLSVRMGKEE
     ELLMINGLGD IMNNKVFYQH PNLMRVLGMH ETVMDVMVNV LGGDKSQIVF PKMVASCCRF
     LCYFCRISRQ NQKAMFEHLS YLLENSSVGL AFPSMRGSTP LDVAAASVMD NNELALALEE
     PDLDKVVTYL AGCGLQSCPV LLAKGYPDIG WNPIEGERYL SFLRFAVFVN SESVEENASV
     VVKLLIRRPE CFGPDLRGEG GNGLLAAMQE AIRISENPAR DLPSQAYKRE GDDDEEEIVH
     MGNAIMSFYS ALIDLLGRCA PEMHLIQSGK GEAIRIRSIL RSLVPTEDLV GIISIPLKLS
     TVNKDGTVNE PDMSANFCPD HKAPMVLFLD RVYGIKDQSF LLHLLEVGFL PDLRASASLD
     TVSLSTTEAA LALNRYICSA VFPLLKRCAP LFSGTEHHAS LVDSMLHTIY RLSKGRSLTK
     AQRDTIEECL LAICHHLRPS MLQQLLRRLV FDVPLLNEYC KMPLKLLTNH YEQCWKYYCL
     PSGMGSYGIA VEEELHLTEK LFWGIFDSLS HKKYDPELFR MALPCLSAIA GALPPDYLDT
     RIRSTLEKQT SLDPEGNFDP KPVSTANLVL PEKLEYIVSR YAEHSHDKWA FDKTNSGWKY
     GVSLDENMKT HPLIRPFKTL TEKEKEIYRW PARESLKTML AMGWSLERTK EGGEATIHQR
     ENEKLRSISQ SSQGNGYSPA PLDLSNVVLS REIQGMVEVM AENYHNIWAK KKKIELESKG
     GGSHPLLVPY DTLTAKEKSR DREKAQDLFK FLQVNGIIIS RGLNEMELDA SSMEKRFAFK
     FLKKILKYID SAQEFVAHLE ALVTSGKTEK SPHEQEIKFF AKVLLPLVDQ YFTNHCLYFL
     SSPTKTLSSS GYASNKEKEM VASLFCKLAA LVRHRISLFG SDSATMVNCL HILAQSLDTR
     TVMKSGSELV KAGLRAFFEN AAEDLEKTSE NLKLGKFTHS RTQIKGVSQN INYTTVALLP
     ILTSIFEHIS QYHFGIDLLL GDVQVSCYRI LCSLYSLGTG KNIYVERQRP ALGECLASLA
     AAIPVAFLEP SLNHYNPLSV FNTKSARERA ILGMPDRVEE MCPEIPQLDG LIKEINNLAE
     SGARYTEMPH VIEVILPMLC NYLSYWWERG SESVPQSAGP CCTMITSEHL SIVLGNILKI
     INNNLGIDEA SWMKRIAVYA QPIISKARPD LLKTHFIPTL EKLKKKAIKI VMEEEQLRAD
     SKADTQEAEL LILDEFAVLC RDLYAFYPIL IRYVDNNRSN WLKKPDADSD ELFRMVAEVF
     ILWCKSHNFK REEQNFVIQN EINNLAFLTG DTKSKMSKSG GQDQERKKSK RRGDLYSIQT
     SLIVAALKKM LPIGLNMCTP GDQELISLAK TRYSHKDTDD EVKEHLRNNL HLQEKSDDPA
     VKWQLNLYKD ILKSDEPTDP ERNVERVQRI SAALYHLEQV EQPLRSKKAV WHKLLSKQRK
     RAVVACFRMA PLYNLPRHRS INLFLHGYQN YWIETEEYSF EEKLVQDLAT PPKKDEEEEE
     ETEKKQPDPL HQIILYFSRS ALTERSKLED DPLYIAYSAM MAKEEEEEEE EEEEKDKTFE
     EKEMEKQRTL YQQARLHDRG AAEMVLQMIS ASKGHTGPMV VETLKLGIAI LNGGNTIVQQ
     KMLDYLKEKK DAGFFQSLSG LMQSCSVLDL NAFERQNKAE GLGMVTEEGT LIVRERGEKV
     LQQDEFTRDL FRFLQLLCEG HNNDFQNYLR TQMGNTTTVN IIISTVDYLL RLQESISDFY
     WYYSGKDVID ESGQRNFSKA LAVTKQIFNS LTEYIQGPCI GNQQSLAHSR LWDAVVGFLH
     VFANMQMKLS QDSAQIELLK ELLDLLKDMV VMLLSLLEGN VVNGTIGKQM VDTLVESSSN
     VEMILKFFDM FLKLKDLTNS DAFKEHDPDS KGIISKKEFQ KSMEAQKQYN MFNYVDFVER
     FHEPAKDIGF NVAVLLTNLS EHMPHDSRLQ SLLEPAESVL NYFEPYLGRI EIMGGAKKIE
     RVYFEISESS RMQWEKPQVK ESKRQFIFDV VNEGGEQEKM ELFVNFCEDT IFEMQLASQI
     SETDSSERPE EEEEAEPSYV VDIEDDEEEE KSLESASAFA MACVAVKKNV ANFFKMVTMK
     NLRKQYRKVK KMTVKEMVKV FFSFFWILFI GIFQLFFTIV WGIFQILWNT VFGGGLVEGA
     KNIKVTKLLG DMPDPTQFGI HDDVMEAEKA EGTEHGVGAE LVQFVKGEKG ETDIFSDIFG
     IHTKKEGSKH GHDAGLGDIA EILGTDIQSS LENTVRKKKG LQISEIAKEA ERERKAEAEK
     ADMEDGEKQD KAKEVQSEQL EEGKMKKKKR RHGQKIEKPE AVMANFFKAL EIYQTKMLHY
     LARNFYNLRF LALFVAFAIN FILLFYKVTE EPLDEVEEDS NLWNSFDEEE EEEGMVFFVL
     EESTGYMAPA LRALAVIHTI ISFVCVIGYY CLKASSVPLV VFKREKEVAR KLEFDGLYIT
     EQPSEDDIKG QWDRLVINTP SFPNNYWDKF VKRKVINKYG DLYGAERIAE LLGLDKSALD
     FSPMEENEPE EASLVSWLSS IDTKYHIWKL GVVFTDNSFL YLAWYTTMSI LGHYNNFFFA
     AHLLDIAMGF KTLRTILSSV THNGKQLVLT VGLLAVVVYL YTVVAFNFFR KFYNKSEDED
     EPDMKCDDMM TCYLFHMYVG VRAGGGIGDE IEDPAGDPYE MYRIVFDITF FFFVIVILLA
     IIQGLIIDAF GELRDQQEQV REDMETKCFI CGIGNDYFDT TPHGFETHTL QEHNLANYLF
     FLMYLINKDE TEHTGQESFV WKMYQERCWD FFPAGDCFRK QYEDQLG
//
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