ID   A0A091W9D8_OPIHO        Unreviewed;       931 AA.
AC   A0A091W9D8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   08-NOV-2023, entry version 29.
DE   SubName: Full=VPS10 domain-containing receptor SorCS2 {ECO:0000313|EMBL:KFR12119.1};
DE   Flags: Fragment;
GN   ORFNames=N306_10399 {ECO:0000313|EMBL:KFR12119.1};
OS   Opisthocomus hoazin (Hoatzin) (Phasianus hoazin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Opisthocomiformes; Opisthocomidae;
OC   Opisthocomus.
OX   NCBI_TaxID=30419 {ECO:0000313|EMBL:KFR12119.1, ECO:0000313|Proteomes:UP000053605};
RN   [1] {ECO:0000313|EMBL:KFR12119.1, ECO:0000313|Proteomes:UP000053605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N306 {ECO:0000313|EMBL:KFR12119.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the VPS10-related sortilin family. SORCS
CC       subfamily. {ECO:0000256|ARBA:ARBA00010818}.
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DR   EMBL; KK735059; KFR12119.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A091W9D8; -.
DR   STRING; 30419.A0A091W9D8; -.
DR   Proteomes; UP000053605; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.10.70.80; -; 1.
DR   Gene3D; 3.30.60.270; -; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR000601; PKD_dom.
DR   InterPro; IPR035986; PKD_dom_sf.
DR   InterPro; IPR031777; Sortilin_C.
DR   InterPro; IPR031778; Sortilin_N.
DR   InterPro; IPR006581; VPS10.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   PANTHER; PTHR12106; SORTILIN RELATED; 1.
DR   PANTHER; PTHR12106:SF9; VPS10 DOMAIN-CONTAINING RECEPTOR SORCS2; 1.
DR   Pfam; PF18911; PKD_4; 1.
DR   Pfam; PF15902; Sortilin-Vps10; 1.
DR   Pfam; PF15901; Sortilin_C; 1.
DR   SMART; SM00602; VPS10; 1.
DR   SUPFAM; SSF110296; Oligoxyloglucan reducing end-specific cellobiohydrolase; 1.
DR   SUPFAM; SSF49299; PKD domain; 1.
DR   PROSITE; PS50093; PKD; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:KFR12119.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053605};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        863..884
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          600..660
FT                   /note="PKD"
FT                   /evidence="ECO:0000259|PROSITE:PS50093"
FT   REGION          911..931
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFR12119.1"
FT   NON_TER         931
FT                   /evidence="ECO:0000313|EMBL:KFR12119.1"
SQ   SEQUENCE   931 AA;  105102 MW;  0C61E4C2F5FF7E6D CRC64;
     IILVSSSHND RDQSLFISTD EGATFQKQPI TFFVETLVFH PKEEDKVLAY TKEGKVYVSI
     DLGKKWILLQ ERVSKDHIFW AVAGVDGDPD LVHMEIQDPS GGYRYITCQI QNCSDKTMTV
     QFAGGTDQDS LTVQDDYIFL QTTAANRTKY YVSYRRNGFV QMKLPKYALP KDLQIISTDE
     NQVFVAVQEW YQTDTYNLYQ SDPQGVYYSI LLENVRSTKQ PEENVKLPMC VVRGVKGVFL
     ANQKIDGKVT TLITYNKGRD WDFLNPPDID MNGKPTNCKP PDCYLHLHLR WADNPYVSGT
     VHTKDTAPGL IMGAGNLGSQ LVEYKEEMYI TSDCGNTWRQ VFEEEHHILY LDHGGVIVAI
     KDTSIPLKIL KFSIDEGQTW STHNFTSTSV FVDGLLSEPG DETLVMTVFG HISYRSDWEL
     VKVDFRPSFP RECTDDDYES WELTNLQGDR CIMGQQRSFR KRKISSWCIK GRSFTSAFTS
     KVCECVNSDF LCDYGFERSA PLKSELSKCF ADFWFNPEAP PEDCVLGQAY TSSTGYRKVV
     SNVCEGGVDL QQNLAQHMCP LIAPRGLQIS IGEESLAVKP GEDITFIVRQ EQGDLLNTKY
     QVDLGDGFKA IYVNLTMTGE PIRHRYENPG IYRVSVKAEN VAGHDEAVMF VQVNSPLQAL
     NLEVVPVVGR NQEVNLTAII LPKNPNLTVF YWWIGNNLQP LLTLESFLVT KFAETGDVRV
     TVQASCGSSM LQDSKVVHVF DHFHVLALKF TKHLDMYNPD IPEWREDIGQ VVTRLLAKET
     KIPEETLMTV VKPGLPTTAD LHVLLPASQP KRKRSVTSDK RIATIKQALN AHNISFFLRG
     GYWVLVTLAD SGSDSQRIGG GGGYWAIVVL FVICLVAVGA FILYKFKRQV TLINNMKLPG
     RNVYAQMHNE KEQEMTSPVN HSEDTQNIIQ G
//