ID   A0A091XKW8_OPIHO        Unreviewed;       529 AA.
AC   A0A091XKW8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 37.
DE   RecName: Full=Importin subunit alpha {ECO:0000256|PIRNR:PIRNR005673};
GN   ORFNames=N306_08618 {ECO:0000313|EMBL:KFR13781.1};
OS   Opisthocomus hoazin (Hoatzin) (Phasianus hoazin).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Opisthocomiformes; Opisthocomidae;
OC   Opisthocomus.
OX   NCBI_TaxID=30419 {ECO:0000313|EMBL:KFR13781.1, ECO:0000313|Proteomes:UP000053605};
RN   [1] {ECO:0000313|EMBL:KFR13781.1, ECO:0000313|Proteomes:UP000053605}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N306 {ECO:0000313|EMBL:KFR13781.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the importin alpha family.
CC       {ECO:0000256|ARBA:ARBA00010394, ECO:0000256|PIRNR:PIRNR005673}.
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DR   EMBL; KK735345; KFR13781.1; -; Genomic_DNA.
DR   RefSeq; XP_009936688.1; XM_009938386.1.
DR   AlphaFoldDB; A0A091XKW8; -.
DR   STRING; 30419.A0A091XKW8; -.
DR   GeneID; 104332931; -.
DR   KEGG; oha:104332931; -.
DR   CTD; 3838; -.
DR   OrthoDB; 916229at2759; -.
DR   PhylomeDB; A0A091XKW8; -.
DR   Proteomes; UP000053605; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0061608; F:nuclear import signal receptor activity; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.20.5.690; Importin-alpha, importin-beta-binding domain; 1.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR032413; Arm_3.
DR   InterPro; IPR000225; Armadillo.
DR   InterPro; IPR002652; Importin-a_IBB.
DR   InterPro; IPR036975; Importin-a_IBB_sf.
DR   InterPro; IPR024931; Importin_alpha.
DR   PANTHER; PTHR23316; IMPORTIN ALPHA; 1.
DR   PANTHER; PTHR23316:SF12; IMPORTIN SUBUNIT ALPHA-1; 1.
DR   Pfam; PF00514; Arm; 8.
DR   Pfam; PF16186; Arm_3; 1.
DR   Pfam; PF01749; IBB; 1.
DR   PIRSF; PIRSF005673; Importin_alpha; 1.
DR   SMART; SM00185; ARM; 8.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50176; ARM_REPEAT; 4.
DR   PROSITE; PS51214; IBB; 1.
PE   3: Inferred from homology;
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW   ECO:0000256|PIRNR:PIRNR005673};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053605};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR005673}.
FT   DOMAIN          1..60
FT                   /note="IBB"
FT                   /evidence="ECO:0000259|PROSITE:PS51214"
FT   REPEAT          119..162
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REPEAT          162..190
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REPEAT          251..293
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REPEAT          293..335
FT                   /note="ARM"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00259"
FT   REGION          43..72
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        55..72
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   529 AA;  58129 MW;  4A4DAC06D02016DE CRC64;
     MSTNENANVA AARLNRFKNK GKDTTEMRRR RIEVNVELRK AKKDDQMLKR RNVSTLPDDA
     TSPLQENRSN QVSAHWSVEE IVRGVNSNNM ELQLQATQAA RKLLSREKQP PIDNIIRAGL
     IPKFVSFLGR ADCSPIQFES AWALTNIASG TSEQTRAVVD GGAIPAFISL LASPHTHISE
     QAVWALGNIA GDGSTYRDLV IKFGAIEPLL SLLAVPDLSS LASGYLRNVT WTLSNLCRNK
     NPAPPIGAIE QILPTLVRLL HHDDREVLAD TCWALSYLTD GSNDRIEVVV KTGLVPQLVK
     LLGCSELPIM TPSLRAIGNI VTGTDEQTQI VIESGALSVF PSLLSHHKNN IQKEAAWTMS
     NITAGRQDQI QQVVDHGLVP YLIGILRKGD FKSQKEAVWA VTNYTSGGTI DQIVYLVQAG
     VVEPLLNLLS AKDSKTVLVI LDAVSNIFLA AEKINETEKL CLMIEECGGL DKIEALQSHE
     NEQVYKASST LIEKYFSAEE EEDQNVVPES TAASYTFHIQ GNTPDTFNF
//