ID A0A093BG43_CHAPE Unreviewed; 963 AA.
AC A0A093BG43;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=alpha-mannosidase {ECO:0000256|ARBA:ARBA00012752};
DE EC=3.2.1.24 {ECO:0000256|ARBA:ARBA00012752};
DE Flags: Fragment;
GN ORFNames=M959_14646 {ECO:0000313|EMBL:KFU93081.1};
OS Chaetura pelagica (Chimney swift) (Hirundo pelagica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Apodiformes; Apodidae;
OC Apodinae; Chaetura.
OX NCBI_TaxID=8897 {ECO:0000313|EMBL:KFU93081.1, ECO:0000313|Proteomes:UP000031515};
RN [1] {ECO:0000313|EMBL:KFU93081.1, ECO:0000313|Proteomes:UP000031515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M959 {ECO:0000313|EMBL:KFU93081.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000031515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=25504712; DOI=10.1126/science.1251385;
RG Avian Genome Consortium;
RA Zhang G., Li C., Li Q., Li B., Larkin D.M., Lee C., Storz J.F., Antunes A.,
RA Greenwold M.J., Meredith R.W., Odeen A., Cui J., Zhou Q., Xu L., Pan H.,
RA Wang Z., Jin L., Zhang P., Hu H., Yang W., Hu J., Xiao J., Yang Z., Liu Y.,
RA Xie Q., Yu H., Lian J., Wen P., Zhang F., Li H., Zeng Y., Xiong Z., Liu S.,
RA Zhou L., Huang Z., An N., Wang J., Zheng Q., Xiong Y., Wang G., Wang B.,
RA Wang J., Fan Y., da Fonseca R.R., Alfaro-Nunez A., Schubert M., Orlando L.,
RA Mourier T., Howard J.T., Ganapathy G., Pfenning A., Whitney O., Rivas M.V.,
RA Hara E., Smith J., Farre M., Narayan J., Slavov G., Romanov M.N.,
RA Borges R., Machado J.P., Khan I., Springer M.S., Gatesy J., Hoffmann F.G.,
RA Opazo J.C., Hastad O., Sawyer R.H., Kim H., Kim K.W., Kim H.J., Cho S.,
RA Li N., Huang Y., Bruford M.W., Zhan X., Dixon A., Bertelsen M.F.,
RA Derryberry E., Warren W., Wilson R.K., Li S., Ray D.A., Green R.E.,
RA O'Brien S.J., Griffin D., Johnson W.E., Haussler D., Ryder O.A.,
RA Willerslev E., Graves G.R., Alstrom P., Fjeldsa J., Mindell D.P.,
RA Edwards S.V., Braun E.L., Rahbek C., Burt D.W., Houde P., Zhang Y.,
RA Yang H., Wang J., Jarvis E.D., Gilbert M.T., Wang J.;
RT "Comparative genomics reveals insights into avian genome evolution and
RT adaptation.";
RL Science 346:1311-1320(2014).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
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DR EMBL; KN126833; KFU93081.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093BG43; -.
DR Proteomes; UP000031515; Unassembled WGS sequence.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10813; GH38N_AMII_Man2C1; 1.
DR Gene3D; 2.60.40.2220; -; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR041147; GH38_C.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF17677; Glyco_hydro38C2; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000031515}.
FT DOMAIN 445..524
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFU93081.1"
FT NON_TER 963
FT /evidence="ECO:0000313|EMBL:KFU93081.1"
SQ SEQUENCE 963 AA; 108004 MW; BB7D03CCA49799CA CRC64;
LSSRWQTCWF KVELSIPPAW AGREVHLVWE SDGEGLVWRD AQPVQGLTKE GEKTSYILTR
SLKETEPHSL TLYVELACNG LFGAGKGSMI APPDPDRRFT LSKAELVVFN RDVYELLVDL
EILLDMAQLL GEENQRSFQA LYTANQMINV CDVTDPSTFP AARDLAAVIF SQRNGQSQHT
IHAMGHCHID SAWLWPYEET IRKCARSWVT VVHLMESNPQ LTFTCSQAQQ FQWVQSWYPG
LYARIRDLVA KGQFIPVGGT WVEMDGNLPS GESMVRQFLQ GQRFFQQQFG QICSEFWLPD
TFGYSAQLPQ LMRGCGIRRF LTQKLSWNLV NTFPHHTFFW EGIDGSRVLT HFPPGDSYGM
QGRVEEMLKT VKNNKDKGRV NHSAFLFGFG DGGGGPTQKM LDRMKRMRDT DGLPRVQLST
PDQLFSVLEK ESSQLCTWVG ELFLELHNGT YTTQAQIKKG NRECERILHD VEVLSTLAVA
RGGTFQYPAS QLQHLWRLLL LNQFHDVLPG SCIQQVVEDA LEYYAEIRRA GAELQEEAVQ
SLCQELLQPG AGSTQSTLVL NTLPWERTEV ISRPGPAGAE ALALVTVPSM GYVIVREPLL
PPQPVAVRKQ EDGSITMENG VIAACLDAMG RLTSLRLLGS QRESVPDGCC ANQFALFDDV
PLYWDAWDVM DYHLETRKPV TGLLKPLEIT LAGGLRGSAS FSLQVGESST LTQEIILDAT
CPFLRFLTQV EWKEAHKFLK VEFPVQVRSP NATYEIQFGH LQRPTHWNTS WDWARFEVWA
HKWLELSEQR FPSVVLRGRM SGLGWQKVSP TFCCLRLRAP KSPDATADIG HHQFTYAVMP
HQGSFQDAGV IQRAYSLNFP LHAVPAGAAQ CPPWSAFSVS SAAVVLEAVK QAEDNPAAVV
ARLYEAHGST AVAWLQTSLP VKEAMLCDLL ERPLAGGRLR LEPRGVPLSF TPFQLLSVLL
VLK
//
