ID A0A093BKJ0_9AVES Unreviewed; 1243 AA.
AC A0A093BKJ0;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 {ECO:0000313|EMBL:KFV04300.1};
DE Flags: Fragment;
GN ORFNames=N339_12045 {ECO:0000313|EMBL:KFV04300.1};
OS Pterocles gutturalis (yellow-throated sandgrouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Ciconiiformes; Pteroclidae; Pterocles.
OX NCBI_TaxID=240206 {ECO:0000313|EMBL:KFV04300.1, ECO:0000313|Proteomes:UP000053149};
RN [1] {ECO:0000313|EMBL:KFV04300.1, ECO:0000313|Proteomes:UP000053149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N339 {ECO:0000313|EMBL:KFV04300.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL228876; KFV04300.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093BKJ0; -.
DR Proteomes; UP000053149; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd00051; EFh; 1.
DR CDD; cd00176; SPEC; 4.
DR Gene3D; 1.20.58.60; -; 9.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.920.20; Gas2-like domain; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR003108; GAR_dom.
DR InterPro; IPR036534; GAR_dom_sf.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR PANTHER; PTHR23169:SF25; MICROTUBULE-ACTIN CROSS-LINKING FACTOR 1, ISOFORMS 1_2_3_4_5; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF02187; GAS2; 1.
DR Pfam; PF00435; Spectrin; 8.
DR SMART; SM00054; EFh; 2.
DR SMART; SM00243; GAS2; 1.
DR SMART; SM00150; SPEC; 10.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 8.
DR PROSITE; PS00018; EF_HAND_1; 2.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS51460; GAR; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000053149}.
FT DOMAIN 1134..1169
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1170..1205
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 1210..1243
FT /note="GAR"
FT /evidence="ECO:0000259|PROSITE:PS51460"
FT REGION 1040..1079
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 196..223
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1040..1055
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1056..1079
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV04300.1"
FT NON_TER 1243
FT /evidence="ECO:0000313|EMBL:KFV04300.1"
SQ SEQUENCE 1243 AA; 143622 MW; 24C972488F983BDA CRC64;
FHDKIELMLE TLESLSSRLC VPPLIPAEVE KIRECIGENK NAMVELEKLQ PSFEALKRRG
EELIGRSQGT DKDLAAKVIQ DKLDQMVFFW ENIKARVEER EMKFLDVLEL AEKFWYDMGA
LLTTIKDTQD IIRDLESPGI DLSIIKQQVE AAETIKEEID GLHEELEFIR LLGTDLIFAC
GETEKPEVKK SIDAMNNMWE SLNKTWNERL EKLEEAMQLA MQYQDTLQAM FDWLDNAVIK
LCNMSPVGTD LNTVKEQMNE MKEFKMEVYQ QQIEMEKLNH QGELVLKKAT DETDRDIIKE
PLTELKHLWE NLGEKIAHRQ HKLEAALLAL GQFQHALAEL MAWLTHTEEL LDAQKPINGD
PKVIEVELAK HHVLKNDVLA HQATVETVNK AGNELLESSA GDDASSLRNC LEMLNSCWEL
VLQKTEEREQ QLQSTLQQAQ GFHGEIEDFL LWLTRMESQL LASKPTGGLP ETAREQLNGH
MELYRQLQAK DDVYSQLRAK GRLVLTEQSV ALLEQKWCLV SSKMEERKAK LEEALALATD
FQNSLQDFIN WLTLAEQSLN VAPPASLILA AVLAQIDEHK VFANEVNAHR DRIIELDQTG
NQLKFLSQKQ DVVLIKNLLV SVQSRWEKVV QRSVERGRAL DDARKRAKQF HEAWKKLIDW
LEDAENHLDS ELEISNDPDK IKLQLSKHKE FQKTLGGKQP VYDTTIRTGR ALKEKALFPD
DTQKLDNLLG EIRDKWDTVC GKSVERQHKL EEALLFSGQF MDALQALVDW LYKVEPQLAE
DQPVHGDLDL VMNLMDAHKV FQKELGKRTG TVQVLKRSGR ELIENSRDDT TWVKVQLQEL
SNRWDTVCKL SVSKQTRLEQ ALKQAEEFRA AVHMLLEWLS EAEQSLRFRG ALPDDAEALQ
SLIDAHKEFM KKVEEKRADV NVAVGMGEVI LAACHPDCIT TIKHWITIIR ARFEEVLTWA
KQHQQRLESA LSELVANAEL LEELLAWIQG AETTLIQQDQ EPMPQNIDQV KVLISEHQSF
MEEMTQKQPD VDRVTKTYKR KATEPPHRPF IEKSHSNRKS LSQATTPSMP IISQSETKNP
RINQLSGRWQ QVWLLALERQ RKLNDALDRL EELKEFANFD FDVWRKKYMR WMNHKKSRVM
DFFRRIDKDQ DGKITRQEFI DGILASKFPT TKLEMTAVAD IFDRDGDGYI DYYEFVAALH
PNKDAYRPTT DADKIEDEVT RQVAQCKCAK RFQVEQIGEN KYR
//
