ID A0A093BQH7_CHAPE Unreviewed; 1054 AA.
AC A0A093BQH7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Double-stranded RNA-specific adenosine deaminase {ECO:0000313|EMBL:KFU91239.1};
DE Flags: Fragment;
GN ORFNames=M959_12900 {ECO:0000313|EMBL:KFU91239.1};
OS Chaetura pelagica (Chimney swift) (Hirundo pelagica).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Apodiformes; Apodidae;
OC Apodinae; Chaetura.
OX NCBI_TaxID=8897 {ECO:0000313|EMBL:KFU91239.1, ECO:0000313|Proteomes:UP000031515};
RN [1] {ECO:0000313|EMBL:KFU91239.1, ECO:0000313|Proteomes:UP000031515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M959 {ECO:0000313|EMBL:KFU91239.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000031515}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=25504712; DOI=10.1126/science.1251385;
RG Avian Genome Consortium;
RA Zhang G., Li C., Li Q., Li B., Larkin D.M., Lee C., Storz J.F., Antunes A.,
RA Greenwold M.J., Meredith R.W., Odeen A., Cui J., Zhou Q., Xu L., Pan H.,
RA Wang Z., Jin L., Zhang P., Hu H., Yang W., Hu J., Xiao J., Yang Z., Liu Y.,
RA Xie Q., Yu H., Lian J., Wen P., Zhang F., Li H., Zeng Y., Xiong Z., Liu S.,
RA Zhou L., Huang Z., An N., Wang J., Zheng Q., Xiong Y., Wang G., Wang B.,
RA Wang J., Fan Y., da Fonseca R.R., Alfaro-Nunez A., Schubert M., Orlando L.,
RA Mourier T., Howard J.T., Ganapathy G., Pfenning A., Whitney O., Rivas M.V.,
RA Hara E., Smith J., Farre M., Narayan J., Slavov G., Romanov M.N.,
RA Borges R., Machado J.P., Khan I., Springer M.S., Gatesy J., Hoffmann F.G.,
RA Opazo J.C., Hastad O., Sawyer R.H., Kim H., Kim K.W., Kim H.J., Cho S.,
RA Li N., Huang Y., Bruford M.W., Zhan X., Dixon A., Bertelsen M.F.,
RA Derryberry E., Warren W., Wilson R.K., Li S., Ray D.A., Green R.E.,
RA O'Brien S.J., Griffin D., Johnson W.E., Haussler D., Ryder O.A.,
RA Willerslev E., Graves G.R., Alstrom P., Fjeldsa J., Mindell D.P.,
RA Edwards S.V., Braun E.L., Rahbek C., Burt D.W., Houde P., Zhang Y.,
RA Yang H., Wang J., Jarvis E.D., Gilbert M.T., Wang J.;
RT "Comparative genomics reveals insights into avian genome evolution and
RT adaptation.";
RL Science 346:1311-1320(2014).
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DR EMBL; KN126622; KFU91239.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093BQH7; -.
DR Proteomes; UP000031515; Unassembled WGS sequence.
DR GO; GO:0003726; F:double-stranded RNA adenosine deaminase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd19913; DSRM_DRADA_rpt1; 1.
DR CDD; cd19914; DSRM_DRADA_rpt2; 1.
DR CDD; cd19915; DSRM_DRADA_rpt3; 1.
DR Gene3D; 3.30.160.20; -; 3.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR002466; A_deamin.
DR InterPro; IPR044456; ADAR1_DSRM_1.
DR InterPro; IPR044457; ADAR1_DSRM_3.
DR InterPro; IPR014720; dsRBD_dom.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR InterPro; IPR042371; Z_dom.
DR PANTHER; PTHR10910:SF107; DOUBLE-STRANDED RNA-SPECIFIC ADENOSINE DEAMINASE; 1.
DR PANTHER; PTHR10910; EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN; 1.
DR Pfam; PF02137; A_deamin; 1.
DR Pfam; PF00035; dsrm; 3.
DR Pfam; PF02295; z-alpha; 2.
DR SMART; SM00552; ADEAMc; 1.
DR SMART; SM00358; DSRM; 3.
DR SMART; SM00550; Zalpha; 2.
DR SUPFAM; SSF54768; dsRNA-binding domain-like; 3.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR PROSITE; PS50141; A_DEAMIN_EDITASE; 1.
DR PROSITE; PS50137; DS_RBD; 3.
DR PROSITE; PS50139; Z_BINDING; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000031515};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884, ECO:0000256|PROSITE-
KW ProRule:PRU00266}.
FT DOMAIN 15..81
FT /note="Z-binding"
FT /evidence="ECO:0000259|PROSITE:PS50139"
FT DOMAIN 113..177
FT /note="Z-binding"
FT /evidence="ECO:0000259|PROSITE:PS50139"
FT DOMAIN 326..394
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 441..509
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 554..622
FT /note="DRBM"
FT /evidence="ECO:0000259|PROSITE:PS50137"
FT DOMAIN 716..1054
FT /note="A to I editase"
FT /evidence="ECO:0000259|PROSITE:PS50141"
FT REGION 72..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 398..437
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFU91239.1"
FT NON_TER 1054
FT /evidence="ECO:0000313|EMBL:KFU91239.1"
SQ SEQUENCE 1054 AA; 115596 MW; 27B75EF12A66F8D7 CRC64;
ERGSDTFRLI FQKLSLAEQD CEQEVLTIFR RLGEGETRTV HDLVRQLNTR KKEVNRVLYK
LCQEGKLHRE GGTPPLWSLA SPKAGRERSP TGHSRAPTDP AGERSTVGSG DTDPIMAETK
DKICNYLFSV AETTALNLAK NIGFSRAKDV NAFLSALEKL GDVHKENTTP PLWSLTDRKR
ERMQMRLKAS AVLQAADPTP EAGFPPSSVP VCPQEMPVAS PAATSEGGLE NGQQAVGQMG
QSNGEAEAAL LEDIKPEFSS LSNYDNSKNG EWATDDIPDN LNAINKQPHE SESIMNSQSS
PSYAAQFEAP FPCTPVEKLL ACQEKNPVSG LTEYSQFTCQ QCEFAMLEQS GPSHEPRFKF
QAVINGRRFP PAEAGSKKLA KQEAAANAMK VLMSEAENGG HSGIKCEDQS SFHSCEPDLP
SHPEPEPPSA PAPLDLLSGK HPISLLTEYG QKSGNTIEFQ LLSQEGPPHD PRFSYCVKMG
DQIFPAVVGN NKKGAKQMAA EVAVKILSGE SVPHVLPEQV QRASFCGPWI ATPDESKVAK
AKGVGELIKY LNVNPVSGLL EYARSNGFAA EFKLIDQSGP PHDPKFVYQA KVGGRWFPAV
TAHSKKQGKQ EAADAALRVL IGETEKMERM EGLNVPEVHS YPNHSMILRF LSPSDLPVSP
LQLPVRGSTL HDQLAMLSHQ RFNTLTARIQ HSLLGRKILA AIVMRRGQAG LGVVVSLGTG
NRCVKGEELS LKGETVNDCH AEIIARRGFV RFLYSELMKY DPSNPSSSEQ SIFEPAGGNR
LKIKSSVTFH LYISTAPCGD GALFDKSCSD QASVMGQTKH QPLFESPKQG KLRTKVENGE
GTIPVESSDI VPTWDGIQHG ERLRTMSCSD KMLRWNVLGL QGALLSHFIE PVYLSSVTLG
YLYSQGHLTR AICCRVARGG NALQKKLQAP YHINHPEVGR VSVYDSARQT GKTKESSVNW
CLADESEVEV LDGTKGKVDG PKLEVSRVSK RKMFALFQQL CAKNNCTDLQ HLSVYSDAKE
AARMYQEAKQ NFFSSLEELG YGSWIRKPQE EDNF
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