ID   A0A093CA89_TAUER        Unreviewed;       337 AA.
AC   A0A093CA89;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating {ECO:0000313|EMBL:KFV12860.1};
DE   Flags: Fragment;
GN   ORFNames=N340_05763 {ECO:0000313|EMBL:KFV12860.1};
OS   Tauraco erythrolophus (Red-crested turaco).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Musophagiformes; Musophagidae; Tauraco.
OX   NCBI_TaxID=121530 {ECO:0000313|EMBL:KFV12860.1, ECO:0000313|Proteomes:UP000053661};
RN   [1] {ECO:0000313|EMBL:KFV12860.1, ECO:0000313|Proteomes:UP000053661}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N340 {ECO:0000313|EMBL:KFV12860.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the 3-beta-HSD family.
CC       {ECO:0000256|ARBA:ARBA00009219, ECO:0000256|RuleBase:RU004475}.
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DR   EMBL; KL460844; KFV12860.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093CA89; -.
DR   Proteomes; UP000053661; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003854; F:3-beta-hydroxy-delta5-steroid dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0006694; P:steroid biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR002225; 3Beta_OHSteriod_DH/Estase.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43245; BIFUNCTIONAL POLYMYXIN RESISTANCE PROTEIN ARNA; 1.
DR   PANTHER; PTHR43245:SF51; SHORT CHAIN DEHYDROGENASE_REDUCTASE FAMILY 42E, MEMBER 2; 1.
DR   Pfam; PF01073; 3Beta_HSD; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|RuleBase:RU004475};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU004475};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053661};
KW   Transmembrane {ECO:0000256|RuleBase:RU004475};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU004475}.
FT   TRANSMEM        261..281
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU004475"
FT   DOMAIN          6..255
FT                   /note="3-beta hydroxysteroid dehydrogenase/isomerase"
FT                   /evidence="ECO:0000259|Pfam:PF01073"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFV12860.1"
FT   NON_TER         337
FT                   /evidence="ECO:0000313|EMBL:KFV12860.1"
SQ   SEQUENCE   337 AA;  37702 MW;  D5F05EA3BA8D823E CRC64;
     GRTCTVIGGS GFLGQHLVEQ LLEKGYVVKV FDIQKRFDND RVQFFLGDLC DKEALLPALR
     GVSVAFHCAS PAPSSDNKEL FYKVNFMGTK AVVEACKEAG VQKLVLTSSA SVVFEGRDIK
     NGSEDLPYAK NPIDYYTETK ILQEKVFGVG WLTFNFFTTA IRPHGIFGPR DPQLVPILIQ
     AAKSGKMKFM IGDGKNLVDF TYVENVVHGH ILAAENLHQD SPLCGKAFHI TNDEPVPFWA
     FMSRILTGLN YDPPKYRVPY WLAYYLALLV SLVLRLLSPL VTIKPTLTPM RVALAGTFHY
     YSCERAKRVM GYKPVVSLDE AIDRTLQSYP HLRQAKA
//