ID   A0A093CGY4_9AVES        Unreviewed;       908 AA.
AC   A0A093CGY4;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 42.
DE   SubName: Full=Protein ECT2 {ECO:0000313|EMBL:KFV13738.1};
GN   ORFNames=N339_08639 {ECO:0000313|EMBL:KFV13738.1};
OS   Pterocles gutturalis (yellow-throated sandgrouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Ciconiiformes; Pteroclidae; Pterocles.
OX   NCBI_TaxID=240206 {ECO:0000313|EMBL:KFV13738.1, ECO:0000313|Proteomes:UP000053149};
RN   [1] {ECO:0000313|EMBL:KFV13738.1, ECO:0000313|Proteomes:UP000053149}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N339 {ECO:0000313|EMBL:KFV13738.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; KL244278; KFV13738.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093CGY4; -.
DR   Proteomes; UP000053149; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:2000431; P:regulation of cytokinesis, actomyosin contractile ring assembly; IEA:InterPro.
DR   CDD; cd17733; BRCT_Ect2_rpt1; 1.
DR   CDD; cd17732; BRCT_Ect2_rpt2; 1.
DR   CDD; cd01229; PH_Ect2; 1.
DR   CDD; cd00160; RhoGEF; 1.
DR   Gene3D; 3.40.50.10190; BRCT domain; 3.
DR   Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR035899; DBL_dom_sf.
DR   InterPro; IPR000219; DH-domain.
DR   InterPro; IPR026817; Ect2.
DR   InterPro; IPR049396; ECT2_BRCT0.
DR   InterPro; IPR049395; ECT2_PH.
DR   InterPro; IPR001331; GDS_CDC24_CS.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   PANTHER; PTHR16777; PROTEIN ECT2; 1.
DR   PANTHER; PTHR16777:SF2; PROTEIN ECT2; 1.
DR   Pfam; PF00533; BRCT; 1.
DR   Pfam; PF21243; ECT2_BRCT0; 1.
DR   Pfam; PF21242; ECT2_PH; 1.
DR   Pfam; PF12738; PTCB-BRCT; 1.
DR   Pfam; PF00621; RhoGEF; 1.
DR   SMART; SM00292; BRCT; 2.
DR   SMART; SM00325; RhoGEF; 1.
DR   SUPFAM; SSF52113; BRCT domain; 2.
DR   SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   PROSITE; PS50172; BRCT; 2.
DR   PROSITE; PS00741; DH_1; 1.
DR   PROSITE; PS50010; DH_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000053149}.
FT   DOMAIN          178..254
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          271..354
FT                   /note="BRCT"
FT                   /evidence="ECO:0000259|PROSITE:PS50172"
FT   DOMAIN          452..635
FT                   /note="DH"
FT                   /evidence="ECO:0000259|PROSITE:PS50010"
FT   REGION          387..449
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        413..449
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   908 AA;  102094 MW;  237FCE72C77D3EEB CRC64;
     MADNSTLVSE TARSLLADSS VLDSKIIETS KENGFPGPVL DVEEEMPQIE TRVVLVQEAG
     KCEELLKALE TIKIMEVPVI KIKETSPGKS EEKLIKSIIH MEIKVPYIKT DTIEELGDCD
     SPEFETIFVV SDFQGSIFNN LCKADCRVVG PPVVLHCAQK GEPLPFSCRP LYCASMLNLV
     LCFTGFRKKD ELVKLVTLVH HMGGIIRKDF SSKVTHLVAN STHGDKFRIA VSLGTPIVKA
     EWIHKAWEKR NEIDFCAADD DFRNQFKVLP FQDCMLSFFG FSDDEKASME EMTEMQGGRY
     LPVGDERCTH LVVEDSTVKD LPFEPLKKLH VVKQEWFWGS IQMDARAGES MYLFEKSDSP
     GLKKSVSLLS LNTPNSNRKR RRLKETLAQL TRETDMSPFP PRKRPSAEHS LSVGSLLDIS
     NTPESSTTSG ETPKSCARPS KNSTPLPVKQ SARWQVAKEL YQTESNYVDI LTTIIQLFQV
     PLEKEGQLGG PILAQEEIKT IFGSIPDILD EDLEDLMMNW TESKSIGDII LKYSKDLLKT
     YPPFVNFFEM SKETITRCEK QKPRFHAFLK INQAKPECGR QSLAELLIRP VQRLPSVALL
     LNDIKKHTAE ENPDKITLER AIESLKEVMT HINEDKRKTE AQRQFFDVVY EVDGCPANLL
     SSHRSLVQRL ETVALGDDLC DRGEQVTLFL FNDCLEIARK RHKVIGAFKS PHGHTRPPAS
     LKHVVLMPLS QIKKVLDIRE TEDCHKAFAL VVRPPTELNN KLLSFQMTTE EPPKEDWLKT
     LCRHVANTIC KADAENLIYT ADPDSVEVNT KDMDSTLSRA SRAIKKTSKK VTRAFSFSKT
     PKRALRRALM SHSATEGRSP SSANEGYIGS RLTSTSSLAG ISSPSLVSLP SIFEKRSHTL
     SRSTTHLI
//