ID   A0A093CLV4_9AVES        Unreviewed;       589 AA.
AC   A0A093CLV4;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Alpha-L-iduronidase {ECO:0000313|EMBL:KFV16845.1};
DE   Flags: Fragment;
GN   ORFNames=N339_10186 {ECO:0000313|EMBL:KFV16845.1};
OS   Pterocles gutturalis (yellow-throated sandgrouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Ciconiiformes; Pteroclidae; Pterocles.
OX   NCBI_TaxID=240206 {ECO:0000313|EMBL:KFV16845.1, ECO:0000313|Proteomes:UP000053149};
RN   [1] {ECO:0000313|EMBL:KFV16845.1, ECO:0000313|Proteomes:UP000053149}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N339 {ECO:0000313|EMBL:KFV16845.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 39 family.
CC       {ECO:0000256|ARBA:ARBA00008875}.
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DR   EMBL; KL249217; KFV16845.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093CLV4; -.
DR   Proteomes; UP000053149; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   InterPro; IPR049165; GH39_as.
DR   InterPro; IPR049167; GH39_C.
DR   InterPro; IPR049166; GH39_cat.
DR   InterPro; IPR000514; Glyco_hydro_39.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR12631; ALPHA-L-IDURONIDASE; 1.
DR   PANTHER; PTHR12631:SF8; ALPHA-L-IDURONIDASE; 1.
DR   Pfam; PF01229; Glyco_hydro_39; 1.
DR   Pfam; PF21200; Glyco_hydro_39_C; 1.
DR   PRINTS; PR00745; GLHYDRLASE39.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
DR   PROSITE; PS01027; GLYCOSYL_HYDROL_F39; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053149}.
FT   DOMAIN          2..471
FT                   /note="Glycosyl hydrolases family 39 N-terminal catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF01229"
FT   DOMAIN          499..586
FT                   /note="Alpha-L-iduronidase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21200"
FT   ACT_SITE        128
FT                   /note="Proton donor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR600514-1"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFV16845.1"
FT   NON_TER         589
FT                   /evidence="ECO:0000313|EMBL:KFV16845.1"
SQ   SEQUENCE   589 AA;  66681 MW;  B22C46B1B53ACE74 CRC64;
     PPLPHSRADL FDLSKDQEMN LAYVSSVPHG GIEQVRIHWL LELVSLRVMN GRLHYNFTAL
     DNLMDCLWEN KLIPGFELMG NPSGYFLDFE DKEQVVRWKN LITLLASRYI DRYGLKHVAK
     WNFETWNEPD HHDFDNVSMT VKGFLNYYDA CSEGLRAASP LLKFGGPGDS FHPLPKSPIC
     WSLLSHCYNG TNFFTGEIGV RLDYISLHKK GGGSSLYILQ QEVEVVEQIQ KLFPNFASVA
     IYNDEADPMV GWSIPQLWRA DVTYAAMVVK VIIQHQNLLI SKANNTINYT LLSNDNAFLS
     YYPHYFTQRT LTARFQMNNT RPPHVQMVRK PVLTVMGLLS LLGEKQIFAE VISSEGKSTQ
     NSTIGVLASV HTPSEMQPSD SWQATLLMYS SDDNRTSSNI STVIVNATHF PKLRELVYMA
     YYLDNNQTNP YLKWKQLGSP DFPSPEQFQQ IRDAEDPVTM GPFPFPEGGI LTLKQDLPIP
     SVFLIHICAR PRSAPDQVTG VRLIPLTKGQ VVVLWDDGCV NSKCIKTFEV GFSPDGRAYQ
     RINAKDTVFT LWVYSPGSSV SGFYRVRAID YWGKAGLSSL PVEYVEAFK
//