ID A0A093CMZ2_TAUER Unreviewed; 702 AA.
AC A0A093CMZ2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Rho GTPase-activating protein 26 {ECO:0000256|ARBA:ARBA00020525};
DE AltName: Full=Rho-type GTPase-activating protein 26 {ECO:0000256|ARBA:ARBA00032211};
DE Flags: Fragment;
GN ORFNames=N340_13463 {ECO:0000313|EMBL:KFV13657.1};
OS Tauraco erythrolophus (Red-crested turaco).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Musophagiformes; Musophagidae; Tauraco.
OX NCBI_TaxID=121530 {ECO:0000313|EMBL:KFV13657.1, ECO:0000313|Proteomes:UP000053661};
RN [1] {ECO:0000313|EMBL:KFV13657.1, ECO:0000313|Proteomes:UP000053661}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N340 {ECO:0000313|EMBL:KFV13657.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell junction, focal adhesion
CC {ECO:0000256|ARBA:ARBA00004246}. Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004608}. Membrane
CC {ECO:0000256|ARBA:ARBA00004370}.
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DR EMBL; KL461972; KFV13657.1; -; Genomic_DNA.
DR Proteomes; UP000053661; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01249; BAR-PH_GRAF_family; 1.
DR CDD; cd12064; SH3_GRAF; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR004148; BAR_dom.
DR InterPro; IPR047234; GRAF_fam.
DR InterPro; IPR035481; GRAF_SH3.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR047225; PH_GRAF.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR12552; OLIGOPHRENIN 1; 1.
DR PANTHER; PTHR12552:SF4; RHO GTPASE-ACTIVATING PROTEIN 26; 1.
DR Pfam; PF16746; BAR_3; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000053661};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 214..318
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 332..513
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT DOMAIN 644..702
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 524..564
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 576..643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 524..540
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..594
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 605..625
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 626..643
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV13657.1"
FT NON_TER 702
FT /evidence="ECO:0000313|EMBL:KFV13657.1"
SQ SEQUENCE 702 AA; 79739 MW; 783A05F3F3F2E324 CRC64;
DLSAAKRKFA DSLNEFKFLC IGDAETDDEI CIAKSLQEFA TVLRNLEDER MRMIENASEV
LITPLEKFRK EQIGAAKDAK KKYDKETEKY CGVLEKHLNL SSKKKESQLQ EADSQVDLVR
QHFYEVSLEY VFKVQEVQER KMFEFVEPLL AFLQGLFTFY HHGYELAKDF SDFKTELTIS
IQNTRNRFEG TRSEVESLMK KMKENPHEHK NISPYTMEGY LYVQEKRHFG TSWVKHYCTY
QRESKRITMV PFDQKSGGKG GEDEAVILKS CTRRKTDSIE KRFCFDVEAV DRPGVITMQA
LSEEDRRLWM EAMDGREPVY NSNKDNQSEG TAQLDNIGFS IIKKCIHAVE TRGINEQGLY
RIVGVNSRVQ KLLSILMDPK TATETETEIC AEWEIKTITS ALKTYLRMLP GPLMMYQFQR
SFIKAAKLEN QESRVSEIHS LVHRLPEXXX XXMNHLAKVA NNHKQNLMTV ANLGVVFGPT
LLRPQEETVA AIMDIKFQNI VVEILIENHE KIFNTVPETA PSNSQLLLSR KKSTDSKPPS
CXXXXSHRAQ PNEKQENRNS IINSSLESVI SSNVNSFLNS NSAPQPSLNS SDLELEVIKP
NRPNSLPQNP SPTSPLSPSW PMFSAPSSPM PTSSTSSDSS PISSPLRKAR ALYACKAEHD
SELSFTAGTV FDNVHPSQEP GWLEGTLNGK TGLIPENYVE FL
//
