ID A0A093CSI4_9AVES Unreviewed; 680 AA.
AC A0A093CSI4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 13-SEP-2023, entry version 25.
DE RecName: Full=glutamine--fructose-6-phosphate transaminase (isomerizing) {ECO:0000256|ARBA:ARBA00012916};
DE EC=2.6.1.16 {ECO:0000256|ARBA:ARBA00012916};
DE Flags: Fragment;
GN ORFNames=N339_09009 {ECO:0000313|EMBL:KFV15247.1};
OS Pterocles gutturalis (yellow-throated sandgrouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Ciconiiformes; Pteroclidae; Pterocles.
OX NCBI_TaxID=240206 {ECO:0000313|EMBL:KFV15247.1, ECO:0000313|Proteomes:UP000053149};
RN [1] {ECO:0000313|EMBL:KFV15247.1, ECO:0000313|Proteomes:UP000053149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N339 {ECO:0000313|EMBL:KFV15247.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-
CC phosphate + L-glutamate; Xref=Rhea:RHEA:13237, ChEBI:CHEBI:29985,
CC ChEBI:CHEBI:58359, ChEBI:CHEBI:58725, ChEBI:CHEBI:61527; EC=2.6.1.16;
CC Evidence={ECO:0000256|ARBA:ARBA00001031};
CC -!- PATHWAY: Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-
CC glucosamine biosynthesis; alpha-D-glucosamine 6-phosphate from D-
CC fructose 6-phosphate: step 1/1. {ECO:0000256|ARBA:ARBA00004775}.
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DR EMBL; KL246695; KFV15247.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093CSI4; -.
DR UniPathway; UPA00113; UER00528.
DR Proteomes; UP000053149; Unassembled WGS sequence.
DR GO; GO:0097367; F:carbohydrate derivative binding; IEA:InterPro.
DR GO; GO:0004360; F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity; IEA:UniProtKB-EC.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR GO; GO:0006048; P:UDP-N-acetylglucosamine biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd00714; GFAT; 1.
DR CDD; cd05008; SIS_GlmS_GlmD_1; 1.
DR CDD; cd05009; SIS_GlmS_GlmD_2; 1.
DR Gene3D; 3.60.20.10; Glutamine Phosphoribosylpyrophosphate, subunit 1, domain 1; 1.
DR InterPro; IPR017932; GATase_2_dom.
DR InterPro; IPR005855; GFAT.
DR InterPro; IPR047084; GFAT_N.
DR InterPro; IPR035466; GlmS/AgaS_SIS.
DR InterPro; IPR035490; GlmS/FrlB_SIS.
DR InterPro; IPR029055; Ntn_hydrolases_N.
DR InterPro; IPR001347; SIS_dom.
DR InterPro; IPR046348; SIS_dom_sf.
DR NCBIfam; TIGR01135; glmS; 1.
DR PANTHER; PTHR10937; GLUCOSAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE, ISOMERIZING; 1.
DR PANTHER; PTHR10937:SF12; GLUTAMINE--FRUCTOSE-6-PHOSPHATE AMINOTRANSFERASE [ISOMERIZING] 1; 1.
DR Pfam; PF13522; GATase_6; 1.
DR Pfam; PF01380; SIS; 2.
DR SUPFAM; SSF56235; N-terminal nucleophile aminohydrolases (Ntn hydrolases); 1.
DR SUPFAM; SSF53697; SIS domain; 1.
DR PROSITE; PS51278; GATASE_TYPE_2; 1.
DR PROSITE; PS51464; SIS; 2.
PE 4: Predicted;
KW Aminotransferase {ECO:0000313|EMBL:KFV15247.1};
KW Glutamine amidotransferase {ECO:0000256|ARBA:ARBA00022962};
KW Reference proteome {ECO:0000313|Proteomes:UP000053149};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KFV15247.1}.
FT DOMAIN 1..286
FT /note="Glutamine amidotransferase type-2"
FT /evidence="ECO:0000259|PROSITE:PS51278"
FT DOMAIN 358..497
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
FT DOMAIN 529..670
FT /note="SIS"
FT /evidence="ECO:0000259|PROSITE:PS51464"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV15247.1"
FT NON_TER 680
FT /evidence="ECO:0000313|EMBL:KFV15247.1"
SQ SEQUENCE 680 AA; 76638 MW; EC1E4E00CA003687 CRC64;
TGIFAYLNYH VPRTRREILE TLIKGLQRLE YRGYDSAGVG FDGGNDKDWE ANACKIQLIK
QKGKVKALDE EVHKQQDMDL DIEFDVHLGI AHTRWATHGE PSPINSHPQR SDKNNEFIVI
HNGIITNYKD LRKFLESKGY DFESETDTES IAKLVKYMYD NRDSDDISFT TLVERVIQQL
EGAFALVFKS VHYPGQAVGT RRGSPLLIGV RSEHKLSTDH IPILYRTGKD KKGSCNLSRV
DSTTCLFPVE EKAVEYYFAS DASAVIEHTN RVIFLEDDDV AAVVDGRLSI HRIKRTAGDH
PGRAVQTLQM ELQQIMKGNF SSFMQKEIFE QPESVVNTMR GRVNFDDYTV NLGGLKDHIK
EIQRCRRLIL IACGTSYHAG VATRQVLEEL TELPVMVELA SDFLDRNTPV FRDDVCFFLS
QSGETADTLM GLRYCKERGA LTVGITNTVG SSISRETDCG VHINAGPEIG VASTKAYTSQ
FVSLVMFALM MCDDRISMQE RRKEIMRGLK GLPDLIKEVL SMDDEIQKLA TELYHQKSVL
IMGRGYHYAT CLEGALKIKE ITYMHSEGIL AGELKHGPLA LVDKLMPVIM IIMRDHTYAK
CQNALQQVIA RQGRPVVICD KEDIETIKNN KRTIKVPHSV DCLQGILSVI PLQLLAFHLA
VLRGYDVDFP RNLAKSVTVE
//
