ID A0A093E014_9AVES Unreviewed; 1071 AA.
AC A0A093E014;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 36.
DE RecName: Full=Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 {ECO:0000256|ARBA:ARBA00016171};
DE AltName: Full=Membrane-associated guanylate kinase inverted 3 {ECO:0000256|ARBA:ARBA00033438};
DE Flags: Fragment;
GN ORFNames=N339_05284 {ECO:0000313|EMBL:KFV07786.1};
OS Pterocles gutturalis (yellow-throated sandgrouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Ciconiiformes; Pteroclidae; Pterocles.
OX NCBI_TaxID=240206 {ECO:0000313|EMBL:KFV07786.1, ECO:0000313|Proteomes:UP000053149};
RN [1] {ECO:0000313|EMBL:KFV07786.1, ECO:0000313|Proteomes:UP000053149}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N339 {ECO:0000313|EMBL:KFV07786.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the MAGUK family.
CC {ECO:0000256|ARBA:ARBA00007014}.
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DR EMBL; KL234230; KFV07786.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093E014; -.
DR Proteomes; UP000053149; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd00992; PDZ_signaling; 5.
DR CDD; cd00201; WW; 2.
DR Gene3D; 2.20.70.10; -; 2.
DR Gene3D; 2.30.42.10; -; 5.
DR Gene3D; 3.30.63.10; Guanylate Kinase phosphate binding domain; 1.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR008144; Guanylate_kin-like_dom.
DR InterPro; IPR020590; Guanylate_kinase_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR10316; MEMBRANE ASSOCIATED GUANYLATE KINASE-RELATED; 1.
DR PANTHER; PTHR10316:SF10; MEMBRANE-ASSOCIATED GUANYLATE KINASE, WW AND PDZ DOMAIN-CONTAINING PROTEIN 3; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR Pfam; PF00595; PDZ; 5.
DR Pfam; PF00397; WW; 2.
DR SMART; SM00072; GuKc; 1.
DR SMART; SM00228; PDZ; 5.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 5.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS00856; GUANYLATE_KINASE_1; 1.
DR PROSITE; PS50052; GUANYLATE_KINASE_2; 1.
DR PROSITE; PS50106; PDZ; 5.
DR PROSITE; PS01159; WW_DOMAIN_1; 2.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 3: Inferred from homology;
KW Kinase {ECO:0000313|EMBL:KFV07786.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000053149};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|EMBL:KFV07786.1}.
FT DOMAIN 9..85
FT /note="Guanylate kinase-like"
FT /evidence="ECO:0000259|PROSITE:PS50052"
FT DOMAIN 188..221
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 234..267
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 305..373
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 474..537
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 621..703
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 745..832
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 914..996
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 77..169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 271..293
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 547..601
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 710..731
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 832..908
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1017..1038
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 108..122
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 142..160
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..293
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 579..594
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 716..731
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 839..854
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1017..1033
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV07786.1"
FT NON_TER 1071
FT /evidence="ECO:0000313|EMBL:KFV07786.1"
SQ SEQUENCE 1071 AA; 116529 MW; CD54404DAD379F83 CRC64;
GKVINKDLRH YLSLQFQKGS IDHKLQQVIR DNLYLRTIPC TTRAPRDGEV PGVDYNFIPV
EQFKALEESG ALLESGTYDG NFYGTPKPPA EPSPFQPDPV DQVLFDNDFD TESQRKRTTS
VSKMQRMDSS LPEEEEEEEK EAVNGSGGIE NKEKHSDSPD WVKPVPSYNQ TSSSMDFRNY
LSRDETLEPL PKNWEMAYTD TGMIYFIDHN TKTTTWLDPR LCKKAKAPED CEDGELPYGW
EKIEDPQYGT YYVDHINQKT QFENPVLEAK RKKQLGQTDA GPSKSGPEKS VFTRDPTQLT
GALIRTSLKK STMGFGFTII GGDRPDEFLQ VKNVLKDGPA AQDGRIAPGD VIVDINGSCV
LGHTHADVVQ MFQLVPVNQY VNMTLCRGYP LPEDSEDPVV DIVTATPIIN GPPGTKGDVC
VSSQDLIAGA IVLDQNGKMA PMLVNGRLNG PSADTAEQRI SLASSGGSQT ELVTIPLVKG
PKGFGFAIAD SPTGQKVKMI LDSQWCQGLQ KGDVIKEICH QNVQSLTHLQ VVEVLKQFPV
GAEVPLLILR GGPPSPTKTA KGKDKQDSSG SLESVGDPIP QPMPFPPSAV RPGSPKPDPS
EVYLKSKTIY EDKPPNTRDL DVFLRKQESG FGFRVLGGDG PDQPIYIGAI IPLGAAEKDG
RLRAADELMC IDGIPVKGKS HKQVLDLMTS AARNGQVLLT VRRKIFFGGE KQPEEESSQP
VLTQNGSPRP NRVEFANQQS PEVYDVRLQR KENEGFGFVI LTSKNKPPPG VIPHKIGRVI
EGSPADQCGK LKVGDRISAV NGQSIVELSH DSIVQLIKDA GNAVTLTVVA EEEHHGPPSG
TNSARQSPAP QHRPLGSAQI NPPGADRGAT EGEAGKEVSN SYRLSWPEHK HLTQPDAGGV
GSRHSQAQNP GCFPVELERG PRGFGFSLRG GKEYNMGLFI LRLAEDGPAV KDGRVHVGDQ
IVEINGEPTQ GITHTRAIEL IQAGGNKVLL LLRPGTGLIP DHGDWDSYNP SSSHVIYEEQ
SPLPSSSHSA SPSEGCYLPV PGEALTNVQL SEKLEQAKNT VPEKISTLTE N
//
