ID A0A093EUT4_TYTAL Unreviewed; 740 AA.
AC A0A093EUT4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Cohesin subunit SA {ECO:0000256|RuleBase:RU369063};
DE AltName: Full=SCC3 homolog {ECO:0000256|RuleBase:RU369063};
DE AltName: Full=Stromal antigen {ECO:0000256|RuleBase:RU369063};
DE Flags: Fragment;
GN ORFNames=N341_08609 {ECO:0000313|EMBL:KFV45114.1};
OS Tyto alba (Barn owl).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV45114.1, ECO:0000313|Proteomes:UP000054190};
RN [1] {ECO:0000313|EMBL:KFV45114.1, ECO:0000313|Proteomes:UP000054190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV45114.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of cohesin complex, a complex required for the
CC cohesion of sister chromatids after DNA replication. The cohesin
CC complex apparently forms a large proteinaceous ring within which sister
CC chromatids can be trapped. At anaphase, the complex is cleaved and
CC dissociates from chromatin, allowing sister chromatids to segregate.
CC {ECO:0000256|RuleBase:RU369063}.
CC -!- SUBUNIT: Part of the cohesin complex which is composed of a heterodimer
CC between a SMC1 protein (SMC1A or SMC1B) and SMC3, which are attached
CC via their hinge domain, and RAD21 which link them at their heads, and
CC one STAG protein. {ECO:0000256|RuleBase:RU369063}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU369063}.
CC Chromosome {ECO:0000256|RuleBase:RU369063}. Chromosome, centromere
CC {ECO:0000256|RuleBase:RU369063}.
CC -!- SIMILARITY: Belongs to the SCC3 family. {ECO:0000256|ARBA:ARBA00005486,
CC ECO:0000256|RuleBase:RU369063}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KK374312; KFV45114.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093EUT4; -.
DR Proteomes; UP000054190; Unassembled WGS sequence.
DR GO; GO:0000785; C:chromatin; IEA:UniProtKB-UniRule.
DR GO; GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.
DR GO; GO:0008278; C:cohesin complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-UniRule.
DR GO; GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
DR GO; GO:0007062; P:sister chromatid cohesion; IEA:UniProtKB-UniRule.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR039662; Cohesin_Scc3/SA.
DR InterPro; IPR020839; SCD.
DR InterPro; IPR013721; STAG.
DR PANTHER; PTHR11199:SF2; SCD DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11199; STROMAL ANTIGEN; 1.
DR Pfam; PF21581; SCD; 1.
DR Pfam; PF08514; STAG; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS51425; SCD; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|RuleBase:RU369063};
KW Cell division {ECO:0000256|RuleBase:RU369063};
KW Chromosome {ECO:0000256|RuleBase:RU369063};
KW Chromosome partition {ECO:0000256|RuleBase:RU369063};
KW Nucleus {ECO:0000256|RuleBase:RU369063};
KW Reference proteome {ECO:0000313|Proteomes:UP000054190}.
FT DOMAIN 140..225
FT /note="SCD"
FT /evidence="ECO:0000259|PROSITE:PS51425"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV45114.1"
FT NON_TER 740
FT /evidence="ECO:0000313|EMBL:KFV45114.1"
SQ SEQUENCE 740 AA; 85925 MW; CAB7297E4860BFCF CRC64;
QDNEDYPLIR TGPYWKKFKA NFCEFIAVLV QQCQCSVLYD SYLMNTIISL LTDLADSMVR
AFRHTSTLAA MKLLTAIVSV HLNLDVNKHN AQRLYEVEKK RISGKRTNYR LDQLEGKRKE
YEHKLLEIQN MMNAIFKGTF LNRYRDVIPE IRATCIEEFG SWIKTYPDVF LNDNYLKYIG
WMLYDKQAEV RLKCLLGLQG IYSRRELVSR MDLFTIRFKD RIVSMLLDKD HEVAVQAMKL
LMLMSQNCED VLSAEDCETL YQFVYTTHRP LAVAAGEFLY KRLLSHEGDE EVQPKGGGKF
GASTEQLKRL IRFFLESELH KHVAYLIDSL WDWAGKFLKD WECMTTLLLK NAEEDGEALS
DAHESALIEI ILATVREAAE GHPPVGRGAA KKILSGKEKK IQLEDCTKIT EHFIMVLPQL
LAKYSTDAQK VVNLLQIPQY YDLDVYSTGR QEKHLDALLR ELKDIVAKHS DMDVLEASSK
TYYILCSEEI AIYSQVDRAL TQLIDELMGQ LNQLLDGFWQ KEEGFCMNAG EISQMHSALR
RVAAFHNAHD LTKWHLYDKI LRLLVFETEH GSLPVLMILP ALQCTYFSLL WQLAAISENS
PKETLYALRR ELRRFSQICL CFLQHKEKDV REKAFMVLCD WLLILSHQDS NNSKEEVGLL
DYLPSTSLQE KLLLFIQEHV FVEEEEESKD LTEEEEREDE SCKLDDLHKK RSLLAAYCKL
IVFNVIEMTA AAEIYKYYVK
//
