ID A0A093EVQ6_TYTAL Unreviewed; 1345 AA.
AC A0A093EVQ6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Sodium channel protein type 2 subunit alpha {ECO:0000313|EMBL:KFV45573.1};
DE Flags: Fragment;
GN ORFNames=N341_11248 {ECO:0000313|EMBL:KFV45573.1};
OS Tyto alba (Barn owl).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV45573.1, ECO:0000313|Proteomes:UP000054190};
RN [1] {ECO:0000313|EMBL:KFV45573.1, ECO:0000313|Proteomes:UP000054190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV45573.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK375235; KFV45573.1; -; Genomic_DNA.
DR Proteomes; UP000054190; Unassembled WGS sequence.
DR GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 3.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR010526; Na_trans_assoc_dom.
DR InterPro; IPR024583; Na_trans_cytopl.
DR InterPro; IPR043203; VGCC_Ca_Na.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10037:SF278; SODIUM CHANNEL PROTEIN TYPE 2 SUBUNIT ALPHA; 1.
DR PANTHER; PTHR10037; VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM; 1.
DR Pfam; PF00520; Ion_trans; 3.
DR Pfam; PF06512; Na_trans_assoc; 1.
DR Pfam; PF11933; Na_trans_cytopl; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion channel {ECO:0000313|EMBL:KFV45573.1};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054190};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT TRANSMEM 258..278
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 771..795
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 807..828
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 890..918
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 980..1003
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1229..1247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1268..1290
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1296..1316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 140..442
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 566..729
FT /note="Voltage-gated Na+ ion channel cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF11933"
FT DOMAIN 779..1010
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 1017..1223
FT /note="Sodium ion transport-associated"
FT /evidence="ECO:0000259|Pfam:PF06512"
FT DOMAIN 1227..1345
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 28..59
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 490..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..649
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1139..1185
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 432..477
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 28..54
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 517..539
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 595..631
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1345
FT /evidence="ECO:0000313|EMBL:KFV45573.1"
SQ SEQUENCE 1345 AA; 152245 MW; 0B0519B3DFEB07CE CRC64;
MAQSVLVPPG PDSFRYFTRE SLAAIEQRVN EEKAKKSKQE RKDDDDEDGP KPNSDLEAGK
TLPFIYGDIP PGMVSEPLED LDPYYINKKT FIVLNKGKAI FRFSATSALY MLTPFNPLRK
IAIKILVHSY PFQVVSLKLM LIMCTILTNC VFMTMSNPPD WTKNVEYTFT GIYTFESLIK
ILARGFCLED FTFLRDPWNW LDFTVITFAY VTEFVDLGNV SALRTFRVLR ALKTISVIPG
LKTIVGALIQ SVKKLSDVMI LTVFCLSVFA LIGLQLFMGN LRNKCLQWPP DNSTFETTVI
SYFNSSIGEN GTFINTTMTT FNWDEYIEDR SHFYFLEGQN DALLCGNSSD AGQCPEGYIC
VKAGRNPNYG YTSFDTFSWA FLSLFRLMTQ DFWENLYQLT LRAAGKTYMI FFVLVIFLGS
FYLINLILAV VAMAYEEQNQ ATMEEAEQKE AEFQQMLEQL KKQQEEAQAA AAAAAADSRD
YSGVGGIGGF SESSSEASKL SSKSAKERRN RRKKKKQKEQ SEGEEKDGEE FHKSESEDSI
KRKGFRFSIE GNRLTYEKRF SSPHQSLLSI RGSLFSPRRN SRTSLFSFRG RAKDVGSEND
FADDEHSTFE DNESRRDSLF VPHRHGERRN SNISQASRSS RTLPPLPANG KMHSTVDCNG
VVSLVGGPPA LTSPTGQLLP EVMIDKAATA SNGTTTETDL RKRRSSSYHV PMDYLTDPSA
RQRAMSIASM LTNTMEELEE SRQKCPPCWY KFANTCLIWD CCTPWLKVKH IVNLIVMDPF
VDLAITICIV LNTLFMAMEH YPMTEQFSGV LSVGNLVFTG IFTAEMFLKI IAMDPYYYFQ
EGWNIFDGFI VSLSLMELGL ANVEGLSVLR SFRLLRVFKL AKSWPTLNML IKIIGNSVGA
LGNLTLVLAI IVFIFAVVGM QLFGKSYKEC VCKISSDCEL PRWHMHDFFH SFLIVFRVLC
GEWIETMWDC MEVAGQTMCL TVFMMVMVIG NLVVLNLFLA LLLSSFSSDN LAATDDDNEM
NNLQIAVARI QKGIDYVKRK VREFIQKAFV RKQKVLDEIK PLEDLNNKKD SCISNHTIVE
IGKNLAYLKE GNGTTSGIGS SVEKYVVDES DYMSFINNPS LTVTVPIAVG ESDFENLNTE
EFSSESDLEE SKEKLNASSS SEGSTVDIGV PPEGEQPEAE PEESLEPEAC FTEGCVRRFK
CCQVSVEDGK GKIWWNLRKT CYKIVEHNWF ETFIVFMILL SSGALAFEDI YIEQRKTIKT
MLEYADKVFT YIFILEMLLK WVAYGFQTYF TNAWCWLDFL IVDVSLVSLT ANALGYSELG
AIKSLRTLRA LRPLRALSRF EGMRV
//
