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Database: UniProt
Entry: A0A093FND6_GAVST
LinkDB: A0A093FND6_GAVST
Original site: A0A093FND6_GAVST 
ID   A0A093FND6_GAVST        Unreviewed;       483 AA.
AC   A0A093FND6;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   07-JUN-2017, entry version 20.
DE   RecName: Full=Sodium channel protein {ECO:0000256|RuleBase:RU361132};
DE   Flags: Fragment;
GN   ORFNames=N328_07675 {ECO:0000313|EMBL:KFV55856.1};
OS   Gavia stellata (Red-throated diver) (Red-throated loon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Gaviiformes; Gaviidae; Gavia.
OX   NCBI_TaxID=37040 {ECO:0000313|EMBL:KFV55856.1, ECO:0000313|Proteomes:UP000054313};
RN   [1] {ECO:0000313|EMBL:KFV55856.1, ECO:0000313|Proteomes:UP000054313}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N328 {ECO:0000313|EMBL:KFV55856.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Mediates the voltage-dependent sodium ion permeability
CC       of excitable membranes. {ECO:0000256|RuleBase:RU361132}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane
CC       {ECO:0000256|RuleBase:RU361132}; Multi-pass membrane protein
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- SIMILARITY: Belongs to the sodium channel (TC 1.A.1.10) family.
CC       {ECO:0000256|RuleBase:RU361132}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|RuleBase:RU361132}.
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DR   EMBL; KK631343; KFV55856.1; -; Genomic_DNA.
DR   Proteomes; UP000054313; Unassembled WGS sequence.
DR   GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR   InterPro; IPR031649; GPHH_dom.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR   InterPro; IPR001696; Na_channel_asu.
DR   Pfam; PF16905; GPHH; 1.
DR   Pfam; PF00520; Ion_trans; 2.
DR   Pfam; PF00612; IQ; 1.
DR   PRINTS; PR00170; NACHANNEL.
DR   SMART; SM00015; IQ; 1.
DR   PROSITE; PS50096; IQ; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000054313};
KW   Ion channel {ECO:0000256|RuleBase:RU361132,
KW   ECO:0000313|EMBL:KFV55856.1};
KW   Ion transport {ECO:0000256|RuleBase:RU361132};
KW   Membrane {ECO:0000256|RuleBase:RU361132};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054313};
KW   Sodium {ECO:0000256|RuleBase:RU361132};
KW   Sodium channel {ECO:0000256|RuleBase:RU361132};
KW   Sodium transport {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane {ECO:0000256|RuleBase:RU361132};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361132};
KW   Transport {ECO:0000256|RuleBase:RU361132};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM      6     25       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    118    136       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    148    167       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    215    237       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   TRANSMEM    304    327       Helical. {ECO:0000256|RuleBase:RU361132}.
FT   DOMAIN        2     33       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN       83    337       Ion_trans. {ECO:0000259|Pfam:PF00520}.
FT   DOMAIN      341    397       GPHH. {ECO:0000259|Pfam:PF16905}.
FT   NON_TER     483    483       {ECO:0000313|EMBL:KFV55856.1}.
SQ   SEQUENCE   483 AA;  55466 MW;  6055E4A5B97845D3 CRC64;
     MYLYFVIFII FGSFFTLNLF IGVIIDNFNQ QKKKISGQDI FMTEEQKKYY NAMKKLGSKK
     PQKPIPRPLN KYQGFIFDVV SKQAFDVSIM ILICLNMVTM MVETDDQSQE KVNILHKINM
     LFVAIFTGEC IIKMLALRHY YFTNGWNIFD FVVVILSIVG TVLSDIIQKY FFSPTLFRVI
     RLARIGRILR LIRGAKGIRT LLFALMMSLP ALFNIGLLLF LVMFIYAIFG MANFAYVKKE
     YGIDDMFNFQ TFANSMLCLF QITTSAGWDG LLNPILNTGP PYCDPNLPNA NGSKGDCGSP
     AVGILFFVTY IIISFLIVVN MYIAIILENF SVATEESTEP LSEDDFDMFY EIWEKFDPEA
     TQFIEYSALS DFADALSEPL RIAKPNKIKL IAMDLPMVSG DRIHCLDILF AFTKRVLGES
     GEMDALKIQM EEKFMAANPS KISYEPITTT LRRKQEEVSA IVIQRAYRRH LFRRSMKQAS
     YLY
//
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