ID A0A093FS18_TYTAL Unreviewed; 613 AA.
AC A0A093FS18;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=diacylglycerol kinase (ATP) {ECO:0000256|ARBA:ARBA00012133};
DE EC=2.7.1.107 {ECO:0000256|ARBA:ARBA00012133};
DE Flags: Fragment;
GN ORFNames=N341_01178 {ECO:0000313|EMBL:KFV59470.1};
OS Tyto alba (Barn owl).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV59470.1, ECO:0000313|Proteomes:UP000054190};
RN [1] {ECO:0000313|EMBL:KFV59470.1, ECO:0000313|Proteomes:UP000054190}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV59470.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=1,2-di-(9Z-octadecenoyl)-sn-glycerol + ATP = 1,2-di-(9Z-
CC octadecenoyl)-sn-glycero-3-phosphate + ADP + H(+);
CC Xref=Rhea:RHEA:40327, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:52333, ChEBI:CHEBI:74546, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00023371};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:40328;
CC Evidence={ECO:0000256|ARBA:ARBA00023371};
CC -!- PATHWAY: Lipid metabolism; glycerolipid metabolism.
CC {ECO:0000256|ARBA:ARBA00005175}.
CC -!- SIMILARITY: Belongs to the eukaryotic diacylglycerol kinase family.
CC {ECO:0000256|ARBA:ARBA00009280}.
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DR EMBL; KK400069; KFV59470.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093FS18; -.
DR UniPathway; UPA00230; -.
DR Proteomes; UP000054190; Unassembled WGS sequence.
DR GO; GO:0004143; F:ATP-dependent diacylglycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0046486; P:glycerolipid metabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0007205; P:protein kinase C-activating G protein-coupled receptor signaling pathway; IEA:InterPro.
DR Gene3D; 2.60.200.40; -; 1.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR017438; ATP-NAD_kinase_N.
DR InterPro; IPR037607; DGK.
DR InterPro; IPR000756; Diacylglycerol_kin_accessory.
DR InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR PANTHER; PTHR11255; DIACYLGLYCEROL KINASE; 1.
DR PANTHER; PTHR11255:SF92; DIACYLGLYCEROL KINASE IOTA; 1.
DR Pfam; PF12796; Ank_2; 1.
DR Pfam; PF00609; DAGK_acc; 1.
DR Pfam; PF00781; DAGK_cat; 1.
DR SMART; SM00248; ANK; 2.
DR SMART; SM00045; DAGKa; 1.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 1.
DR PROSITE; PS50146; DAGK; 1.
PE 3: Inferred from homology;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:KFV59470.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054190};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 1..70
FT /note="DAGKc"
FT /evidence="ECO:0000259|PROSITE:PS50146"
FT REPEAT 542..574
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 570..590
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 570..584
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV59470.1"
FT NON_TER 613
FT /evidence="ECO:0000313|EMBL:KFV59470.1"
SQ SEQUENCE 613 AA; 69356 MW; 1A4357C4AA073D2F CRC64;
VGWILSILDE LQLSPPPPVA VLPLGTGNDL ARTLNWGGGY TDEPVSKILC HVEDGTIVQL
DRWNLQVERN PDLPQDELED GARKLPLSVF NNYFSLGFDA HVTLEFHESR EANPEKFNSR
FRNKMFYAGA AFTDFLQRSS RDLSKHVKVV CDGTDLTPKI QELKFQCIVF LNIPRYCAGT
MPWGNPGDHR DFEPQRHDDG YIEVIGFTMA SLAALQVGGH GERLHQCREV TLLTYKSIPM
QVDGEPCRLA PSLIRISLRN QANMVQKSKR RTSMPLLNDP HSIPDRLRIR VNRINLQEYE
GLHYDKEKLR EASIPLGIIV VRGDCDLETC RMYIDRLQED LQSVTSTTQR VHYQDQESSF
PRVLSVQRLS PRWCFLDATS ADRFYRIDRS QEHLHFVTEI SQDEIFILDP ELVMSECLSL
PSFLPRISDR WNPAVRKRML SDSGLGKISP HYEVPDKQKD ASQTHMLQSP VSSEDQALLQ
AVIAGDLLKF IECCKKGANL LIQGPDHCSL LHHAAKTGQG EIVKYILEHG PSELLDMTDS
ETGETALHKA ACQRHRAICQ LLVDAGASLR KTDSKGKTPR DRAQQAGDPD LASYLDSRQN
YQMVSHEDLE TAV
//
