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Database: UniProt
Entry: A0A093FYU4_TYTAL
LinkDB: A0A093FYU4_TYTAL
Original site: A0A093FYU4_TYTAL 
ID   A0A093FYU4_TYTAL        Unreviewed;       717 AA.
AC   A0A093FYU4;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   08-JUN-2016, entry version 8.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
DE   Flags: Fragment;
GN   ORFNames=N341_06888 {ECO:0000313|EMBL:KFV59566.1};
OS   Tyto alba (Barn owl).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Strigiformes; Tytonidae; Tyto.
OX   NCBI_TaxID=56313 {ECO:0000313|EMBL:KFV59566.1, ECO:0000313|Proteomes:UP000054190};
RN   [1] {ECO:0000313|EMBL:KFV59566.1, ECO:0000313|Proteomes:UP000054190}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N341 {ECO:0000313|EMBL:KFV59566.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; KK400247; KFV59566.1; -; Genomic_DNA.
DR   Proteomes; UP000054190; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000054190};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054190};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    314    338       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    358    377       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    455    476       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    482    506       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    547    571       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    686    713       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   COILED        5     39       {ECO:0000256|SAM:Coils}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFV59566.1}.
FT   NON_TER     717    717       {ECO:0000313|EMBL:KFV59566.1}.
SQ   SEQUENCE   717 AA;  81529 MW;  17446480D07887BC CRC64;
     LPFPLYVLQA NFEKIENELK EINTNQEALK RNFLELTELK FILRKTQQFF DEVRIPGADL
     LEESSSLLEP SEMGRGAPLR LGFVAGVINR ERIPMFERML WRVCRGNVFL RQAEIENPLE
     DPVTGDYVHK SVFIIFFQGD QLKNRVKKIC EGFRASLYPC PETPQERKEM ASGVNTRIDD
     LQMVLNQTED HRQRVLQAAA KNIRVWFIKV RKMKAIYHTL NLCNIDVTQK CLIAEVWCPV
     ADLDSIQFAL RRGTEHSGST VPSILNRMQT NQTPPTYNKT NKFTSGFQNI VDAYGIGTYR
     EINPAPYTII TFPFLFAVMF GDFGHGILMT LIAVWMVLRE SRILSQKSDN EMFNMVFSGR
     YIILLMGLFS TYTGLIYNDC FSKSLNMFGS SWSVRPMFSK GNWSDALLES TPLLQLNPAI
     PGVFGGPYPF GIDPIWNIAS NKLAFLNSFK MKMSVILGII HMLFGVTLSL LNHIYFKKPL
     NIYLGFIPEI IFMSSLFGYL VILIFYKWTA YDAYTSKDAP SLLIHFINMF LFSYSDTSNK
     MLYKGQQGLQ CFLVVVALLC VPWMLVAKPL VLRHQYLRRK HLVGTRGSSG CNSSVLFPRP
     ASPCCLQGSR LSSFSVFSLQ FDFGDTVVYQ AIHTIEYCLG CISNTASYLR LWALSLAHAQ
     LSEVLWTMVI HIGLSVRSLG GGFGLFFIFA AFATLTVAIL LVMEGLSAFL HALRLHW
//
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