ID   A0A093I7P5_EURHL        Unreviewed;       491 AA.
AC   A0A093I7P5;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=GATOR complex protein NPRL3 {ECO:0000256|RuleBase:RU368069};
DE   AltName: Full=Nitrogen permease regulator 3-like protein {ECO:0000256|RuleBase:RU368069};
DE   Flags: Fragment;
GN   ORFNames=N326_07223 {ECO:0000313|EMBL:KFV98739.1};
OS   Eurypyga helias (Sunbittern) (Ardea helias).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Eurypygimorphae; Eurypygiformes;
OC   Eurypygidae; Eurypyga.
OX   NCBI_TaxID=54383 {ECO:0000313|EMBL:KFV98739.1, ECO:0000313|Proteomes:UP000054232};
RN   [1] {ECO:0000313|EMBL:KFV98739.1, ECO:0000313|Proteomes:UP000054232}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N326 {ECO:0000313|EMBL:KFV98739.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: As a component of the GATOR1 complex functions as an
CC       inhibitor of the amino acid-sensing branch of the TORC1 pathway.
CC       {ECO:0000256|RuleBase:RU368069}.
CC   -!- SUBCELLULAR LOCATION: Lysosome {ECO:0000256|RuleBase:RU368069}.
CC   -!- SIMILARITY: Belongs to the NPR3 family. {ECO:0000256|ARBA:ARBA00010546,
CC       ECO:0000256|RuleBase:RU368069}.
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DR   EMBL; KK556924; KFV98739.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093I7P5; -.
DR   Proteomes; UP000054232; Unassembled WGS sequence.
DR   GO; GO:1990130; C:GATOR1 complex; IEA:UniProtKB-UniRule.
DR   GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0034198; P:cellular response to amino acid starvation; IEA:UniProtKB-UniRule.
DR   GO; GO:0032007; P:negative regulation of TOR signaling; IEA:InterPro.
DR   InterPro; IPR005365; Npr3.
DR   PANTHER; PTHR13153; CGTHBA PROTEIN -14 GENE PROTEIN; 1.
DR   PANTHER; PTHR13153:SF5; GATOR COMPLEX PROTEIN NPRL3; 1.
DR   Pfam; PF03666; NPR3; 1.
PE   3: Inferred from homology;
KW   Lysosome {ECO:0000256|RuleBase:RU368069};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054232};
KW   Signal {ECO:0000256|RuleBase:RU368069}.
FT   REGION          377..420
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        379..412
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KFV98739.1"
FT   NON_TER         491
FT                   /evidence="ECO:0000313|EMBL:KFV98739.1"
SQ   SEQUENCE   491 AA;  55400 MW;  AFC9AE9BFB9D86F4 CRC64;
     SRFSDVILAT ILATKSDMCG KKFELKIDNV RFVGHPTLLQ HALGQVSKTD PSPKREMPTM
     ILFNVVFALR ANADPSVINC LHNLSRRIAI VLQHEERRCQ YLTREAKLIL AIQDEVSAMS
     ETTEGPQSPF HHILPKCKLA RDLKETYDSL CTTGVVRLHI NNWLEVSFCL PHKIHYVATN
     FIPPEAIERS LKSIRPYHAL LLLNDEKSLL NELPLDCSPA LVRVIKTTSA VKNLQQLAQD
     ADLALLQVFQ LAAHLVYWGK AIIIYPLCEN NVYMLSPNAS VCLGMASKWG CSPFALRDPG
     RRRAAVSRRG SGCTVPVLLE GVNTSFLTPQ TQLIQMVIWM LQHRLLIQLH TYVCLMVPPN
     EEDFRAQDED MPFTARVGGR SLSTPNALSF GSPTSSDDMT LTSPSMDNSS AELIPGGDSP
     LNKRMTENLL ASLLEHEREA ILNVPAAQNP EDLRMFARLL HYFRGRHHLE EIMYNENMRR
     SQLLMLFDKF R
//