ID A0A093IRU7_FULGA Unreviewed; 1039 AA.
AC A0A093IRU7;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 08-NOV-2023, entry version 44.
DE RecName: Full=Anion exchange protein {ECO:0000256|RuleBase:RU362035};
DE Flags: Fragment;
GN ORFNames=N327_07402 {ECO:0000313|EMBL:KFW04388.1};
OS Fulmarus glacialis (Northern fulmar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Procellariiformes; Procellariidae;
OC Fulmarus.
OX NCBI_TaxID=30455 {ECO:0000313|EMBL:KFW04388.1, ECO:0000313|Proteomes:UP000053806};
RN [1] {ECO:0000313|EMBL:KFW04388.1, ECO:0000313|Proteomes:UP000053806}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N327 {ECO:0000313|EMBL:KFW04388.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Basolateral cell membrane
CC {ECO:0000256|ARBA:ARBA00004554}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004554}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651}. Lateral cell membrane
CC {ECO:0000256|ARBA:ARBA00034693}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00034693}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362035}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362035}.
CC -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31) family.
CC {ECO:0000256|ARBA:ARBA00010993, ECO:0000256|RuleBase:RU362035}.
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DR EMBL; KK597904; KFW04388.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093IRU7; -.
DR Proteomes; UP000053806; Unassembled WGS sequence.
DR GO; GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016328; C:lateral plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR Gene3D; 1.10.287.570; Helical hairpin bin; 1.
DR InterPro; IPR013769; Band3_cytoplasmic_dom.
DR InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR InterPro; IPR003020; HCO3_transpt_euk.
DR InterPro; IPR003024; Na/HCO3_transpt.
DR InterPro; IPR016152; PTrfase/Anion_transptr.
DR NCBIfam; TIGR00834; ae; 1.
DR PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR PANTHER; PTHR11453:SF37; ELECTRONEUTRAL SODIUM BICARBONATE EXCHANGER 1; 1.
DR Pfam; PF07565; Band_3_cyto; 1.
DR Pfam; PF00955; HCO3_cotransp; 1.
DR PRINTS; PR01231; HCO3TRNSPORT.
DR PRINTS; PR01232; NAHCO3TRSPRT.
DR SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW ECO:0000256|RuleBase:RU362035};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362035};
KW Reference proteome {ECO:0000313|Proteomes:UP000053806};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362035};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362035};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU362035}.
FT TRANSMEM 455..477
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 489..513
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 533..556
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 568..586
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 670..688
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 708..726
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 756..775
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 796..820
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 856..875
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 882..901
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT TRANSMEM 928..945
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362035"
FT DOMAIN 125..382
FT /note="Band 3 cytoplasmic"
FT /evidence="ECO:0000259|Pfam:PF07565"
FT DOMAIN 426..934
FT /note="Bicarbonate transporter-like transmembrane"
FT /evidence="ECO:0000259|Pfam:PF00955"
FT REGION 40..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 221..254
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 988..1039
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..56
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 238..254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..421
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 988..1028
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW04388.1"
FT NON_TER 1039
FT /evidence="ECO:0000313|EMBL:KFW04388.1"
SQ SEQUENCE 1039 AA; 118033 MW; F13235B0E80E4BB6 CRC64;
RHDEEAVIDQ GRTSNVVNIH YEKEELEGHR TLYVGVRMPL VRQSHRHHRP HSQKHRKRER
EKDSALTEQG YHYTPSQRVQ FILGTEEDEQ HVPHDLFTEL DEICVKDGED AEWKETARWL
KFEEDVEDGG ERWSKPYVAT LSLHSLFELR SCIINGTVLL DICANSIEEI ADMILSQQEQ
SPEFDERMQA KVREVLLKKH HHQNEKKRNN LLPIVRSFAD GSKKQSDPHL LDKPAQTLTP
HPSPTTAEAK NGVNHETSAM DLSKAELHFM KKIPTGAEAS NVLVGELDFL HQPIVAFVRL
TPAVLLSGMT EVPIPTRFLF VLLGPEGKAH QYHEIGRSMA TIMTDEVFHD VAYKAKNRAD
LVAGIDEFLD QVTVLPPGEW DPSIRIEPPK NVPSQEKRKM PGALDDSTSH SKPEKHSGPE
LEQTGRLFGG LILDVKRKAP WFWSDFRDGL SLQCLASFLF LYCACMSPVI TFGGLLGEAT
SGHISAMESL LGASMTGVVY SLFAGQPLTI LGSTGPVLVF EKILYKFCQD YTLSYLSLRA
CIGLWTTFFC IVLVATDASC LVCYITRFTE EAFASLICII FIYEALEKLS HLRETYPVHM
HSKLDFLTIY YCKCEAPTHP SNETLRFWES NKINVSGITW ENLTVTECRY LHGEFQGPAC
GHNGPYTPNV LFWCCILFFS TFVLSSLLKK FKTSRYFPTR VRSTISDFAV FLTIVIMVLI
DFMIGIPSPK LHVPHMFKPT RDDRGWFINP IGPNPWWTVL AALIPALLCT ILIFMDQQIT
AVIVNRKEHR LKKGCGYHLD LLMVAVMLGV CSVMGLPWFV AATVLSITHV NSLKVESNCS
APGEHPKFLG IREQRVTGLM IFVLMGCSVF FTSVLKFIPM PVLYGVFLYM GVSSLRGIQF
FDRLKLFWMP AKHQPDFIYL RHVPLRKVHF FTLIQLLCLV LLWGIKASRA AIIFPMMVLA
LVFVRKVMDF CFSKRELSFL DDLMPESKKK KLDDAKNEAK EEELKLGKTS DLDIPKQNSD
RADPSEINIS DEMSKTTVW
//
