ID A0A093IV50_EURHL Unreviewed; 857 AA.
AC A0A093IV50;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=VPS10 domain-containing receptor SorCS3 {ECO:0000313|EMBL:KFW02644.1};
DE Flags: Fragment;
GN ORFNames=N326_12315 {ECO:0000313|EMBL:KFW02644.1};
OS Eurypyga helias (Sunbittern) (Ardea helias).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Eurypygimorphae; Eurypygiformes;
OC Eurypygidae; Eurypyga.
OX NCBI_TaxID=54383 {ECO:0000313|EMBL:KFW02644.1, ECO:0000313|Proteomes:UP000054232};
RN [1] {ECO:0000313|EMBL:KFW02644.1, ECO:0000313|Proteomes:UP000054232}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N326 {ECO:0000313|EMBL:KFW02644.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the VPS10-related sortilin family. SORCS
CC subfamily. {ECO:0000256|ARBA:ARBA00010818}.
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DR EMBL; KK563154; KFW02644.1; -; Genomic_DNA.
DR RefSeq; XP_010147161.1; XM_010148859.1.
DR AlphaFoldDB; A0A093IV50; -.
DR GeneID; 104507540; -.
DR KEGG; ehs:104507540; -.
DR CTD; 22986; -.
DR OrthoDB; 5840at2759; -.
DR Proteomes; UP000054232; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.10.70.80; -; 1.
DR Gene3D; 3.30.60.270; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000601; PKD_dom.
DR InterPro; IPR035986; PKD_dom_sf.
DR InterPro; IPR031777; Sortilin_C.
DR InterPro; IPR031778; Sortilin_N.
DR InterPro; IPR006581; VPS10.
DR PANTHER; PTHR12106; SORTILIN RELATED; 1.
DR PANTHER; PTHR12106:SF10; VPS10 DOMAIN-CONTAINING RECEPTOR SORCS3; 1.
DR Pfam; PF00801; PKD; 1.
DR Pfam; PF15902; Sortilin-Vps10; 1.
DR Pfam; PF15901; Sortilin_C; 1.
DR SMART; SM00602; VPS10; 1.
DR SUPFAM; SSF110296; Oligoxyloglucan reducing end-specific cellobiohydrolase; 1.
DR SUPFAM; SSF49299; PKD domain; 2.
DR PROSITE; PS50093; PKD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:KFW02644.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054232};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 761..779
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 495..539
FT /note="PKD"
FT /evidence="ECO:0000259|PROSITE:PS50093"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW02644.1"
FT NON_TER 857
FT /evidence="ECO:0000313|EMBL:KFW02644.1"
SQ SEQUENCE 857 AA; 96547 MW; 69ECA9F37413B512 CRC64;
THYLTCRIQE CSETKRSGPF SRSIDISSLV VQDEYIFIQV TTSGRANYYV SYRREPFAQI
KLPKYSLPKD MHIISTDEKQ VFAAVQEWNQ NDTYNLYISD TQGVYFTLAL ENVKSSRGLE
GNIIIDLYEV AGIKGIFLAN RKIDDQIKTF ITYNKGRDWR LLQAPDTDLR GDPVVCQMPF
CSLHLHLQLS ENPYTSGSIS SKETAPGLLV ATGNIGSELS YTDVGVFISS DGGNSWRQIF
EEEYNVWFLD WGGALVAMKH TSVPIRHMWV SFDEGRSWSK YSFTSTPLFV DGSLVDPGIE
TQIMTVFGHF SLRSEWQLVK VDYKSLFSRR CNKDDYQTWH LHNQGEPCVM GERKIYKKRK
PGAQCSLGRD YSQTVVSEPC VCSQGDFECD YGYERHRNNQ CVPAFWFSPS SLSRDCSIGQ
SYLNSTGYRR IVSNNCTDGL REKYMAKMEK CPGKAPRGLH ILTADGKLVT EQGRNATFII
LMEEGDLQRT NIQLDFGDGI AVSYANFSPV EDGIRHVYKS AGIFQVTAYA ENSLGSDTAV
LFLHVVCPVE HVHLSVPFVA IRNKDVNITA VVWPSQAGTL TYFWWFGNST KPLITLESSI
SYIFAMEGMN TVTVQVSAGN TLIQDTKEIA VHEYFQSQLL SFSPNLDYHN PDIPEWRQDI
GKVIKRALTQ VTGIPEEQIL VAVFPGLPTS AELFILPHKN TTERRKSSDA DLEQVVEILF
NALNQNLVQF ELKPGVEVIV YVTQLTLAPL VDSSTGHSSS AMLMLLSVVF VGLAVFLIYK
FKRKIPWINI YAQVQHDKEQ EMIGSVSQSE NAPKITLSEF TDPEELMDKE LDTRVMGSIS
TIANSESTKE IPNCTSV
//
