ID A0A093JAX4_STRCA Unreviewed; 652 AA.
AC A0A093JAX4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=Neurofilament medium polypeptide {ECO:0000256|ARBA:ARBA00015894};
DE AltName: Full=160 kDa neurofilament protein {ECO:0000256|ARBA:ARBA00030258};
DE AltName: Full=Neurofilament triplet M protein {ECO:0000256|ARBA:ARBA00032778};
DE Flags: Fragment;
GN ORFNames=N308_01100 {ECO:0000313|EMBL:KFV76074.1};
OS Struthio camelus australis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC Struthio.
OX NCBI_TaxID=441894 {ECO:0000313|EMBL:KFV76074.1, ECO:0000313|Proteomes:UP000053584};
RN [1] {ECO:0000313|EMBL:KFV76074.1, ECO:0000313|Proteomes:UP000053584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N308 {ECO:0000313|EMBL:KFV76074.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR EMBL; KL205882; KFV76074.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093JAX4; -.
DR STRING; 441894.ENSSCUP00000002828; -.
DR Proteomes; UP000053584; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR PANTHER; PTHR45652; GLIAL FIBRILLARY ACIDIC PROTEIN; 1.
DR PANTHER; PTHR45652:SF3; NEUROFILAMENT MEDIUM POLYPEPTIDE; 1.
DR Pfam; PF00038; Filament; 2.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685};
KW Reference proteome {ECO:0000313|Proteomes:UP000053584}.
FT DOMAIN 25..248
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 319..524
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 538..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 15..168
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 192..219
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 319..340
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 352..394
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 395..435
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 470..524
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 542..573
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 583..602
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV76074.1"
FT NON_TER 652
FT /evidence="ECO:0000313|EMBL:KFV76074.1"
SQ SEQUENCE 652 AA; 72243 MW; 6F24DE4B652B3755 CRC64;
AGALDGSQSS LLNGAAELKL SRSNEKEQLQ GLNDRFAGYI EKVHYLEQQN KEIEAELAAL
RQKHAGRAQL GDAYEQELRE LRGVLEQVSH EKAQIQLDSE HIEEDIQRLR ERFEDEARLR
DETEATIRAL RKDMEEASLM RAELDKKVQS LQDEVAFLRG NHEEEVAELL AQLQASHATV
ERKDSLCHRG FARLLQDTIH QLENELRGTK WEMARHLREY QDLLNVKMAL DIEIAAYRKL
LEGEETRFSA FSGSITGPLF THRQPSVTIT SKIQKKAEPP KLKVQHKFVE EIIEETKVED
EKSEMEDALA AIAEEIAAKA QQEQEEKKAE EGEAVAEEIA PEKAAAEQAA APEEEKEEEA
EEEEAVKSDE AEEGGSEKEE IEEKEGEEAE EEGEEAEAKG KGEAEEADAT VAGAKKEEKV
GEKAAKEEEK AAPVEKPATP KAASPDKAAT PEKPASPEKP ATPEKAAALE KPVTPEKLRS
PEKPATPEKA VTPEKLRSPE KPVTPEKPRS PEKPASPVKD EKPVVEETIT VTKVTKVSAE
VEASKGSRKE DIAVNGEVEE KKEEKEAEEE GKGVVTNGLD VSPTDDKGEK AVVTKKEKIT
SEGGDGTTTY ITKSVTVTQK VEEHEESFEE KLVSTKKVEK VTSHAVVKEI KE
//
