ID A0A093JWG4_STRCA Unreviewed; 691 AA.
AC A0A093JWG4;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 22-FEB-2023, entry version 28.
DE SubName: Full=Rho GTPase-activating protein 22 {ECO:0000313|EMBL:KFV82834.1};
DE Flags: Fragment;
GN ORFNames=N308_09058 {ECO:0000313|EMBL:KFV82834.1};
OS Struthio camelus australis.
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae;
OC Struthio.
OX NCBI_TaxID=441894 {ECO:0000313|EMBL:KFV82834.1, ECO:0000313|Proteomes:UP000053584};
RN [1] {ECO:0000313|EMBL:KFV82834.1, ECO:0000313|Proteomes:UP000053584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N308 {ECO:0000313|EMBL:KFV82834.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL206495; KFV82834.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093JWG4; -.
DR STRING; 441894.ENSSCUP00000014223; -.
DR Proteomes; UP000053584; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd13378; PH_RhoGAP2; 1.
DR CDD; cd04390; RhoGAP_ARHGAP22_24_25; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15228:SF22; RHO GTPASE-ACTIVATING PROTEIN 22; 1.
DR PANTHER; PTHR15228; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW Reference proteome {ECO:0000313|Proteomes:UP000053584}.
FT DOMAIN 26..134
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 144..338
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 364..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 603..679
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 406..425
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV82834.1"
FT NON_TER 691
FT /evidence="ECO:0000313|EMBL:KFV82834.1"
SQ SEQUENCE 691 AA; 77245 MW; BEB03FAB5CE84792 CRC64;
ARSKSLVMGE QIGPPSRPSS PNPQERMLKC GWLKKQRSIM KHWQQRWFVL RGDQLLYYKD
EEETKPQGFI PLQGNQVNEL PPNPDEPGKH LFEIAPGGAG DREKMPVNHE AFLLMANSQN
EMEDWVKAIR RVIWAPFGGG IFGQRLEDTV QYERKYGQRL APLLVEQCAD FIRERGLTEE
GLFRMPGQAN LVKDLQDSFD CGEKPLFDSN TDVHTVASLL KLYLRELPEP VIPFAKYEDF
ISCGQLLSKD EGEGTQELVK QVKNLPQANY NLLKYICKFL DEVQAYSSVN KMSVQNLATV
FGPNILRPKM EDPVTMMEGT SLVQHLMTVL ISEQGRIFAV PQTDVPGSQL EIRPVRQRNT
VEWISEEDGE DSRSENSVSS PADLPSGNAV AVEPTPGPVV KNTPPERSGK LTQPATSPSK
RVQTLPPWKY SFRQQGARSV SPKLGSSSLD IPNLSSGGNW LMNGLYSLRG HRRTASGERV
KDSCSSQRLS TYDNVPSSSL SLSTHSMAST TWSTSSCEIS VVDSVSSCPA CRASDSSALS
SLKTEWVTQG SLSQSEVKTA DLENSTDRIY ACSSSSEQSN PAAASRDSVK CSRALQSLVV
ELKTELSKQR TEYETSIKRL EEASADLRKQ VVRLEEELDQ ERKKYTMLEI KLRNSERARE
DAEKRNHLLQ KEMEEFFSTL GCLTFGSQSA K
//
