ID A0A093KIT2_EURHL Unreviewed; 521 AA.
AC A0A093KIT2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Ephexin-1 {ECO:0000313|EMBL:KFV97685.1};
DE Flags: Fragment;
GN ORFNames=N326_07868 {ECO:0000313|EMBL:KFV97685.1};
OS Eurypyga helias (Sunbittern) (Ardea helias).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Eurypygimorphae; Eurypygiformes;
OC Eurypygidae; Eurypyga.
OX NCBI_TaxID=54383 {ECO:0000313|EMBL:KFV97685.1, ECO:0000313|Proteomes:UP000054232};
RN [1] {ECO:0000313|EMBL:KFV97685.1, ECO:0000313|Proteomes:UP000054232}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N326 {ECO:0000313|EMBL:KFV97685.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK555195; KFV97685.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093KIT2; -.
DR Proteomes; UP000054232; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd01221; PH_ephexin; 1.
DR CDD; cd00160; RhoGEF; 1.
DR CDD; cd11939; SH3_ephexin1; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR035635; Ephexin-1_SH3.
DR InterPro; IPR047271; Ephexin-like.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR047270; PH_ephexin.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR12845:SF8; EPHEXIN-1; 1.
DR PANTHER; PTHR12845; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000054232};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 90..274
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 306..418
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 429..490
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 9..54
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..27
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..54
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFV97685.1"
FT NON_TER 521
FT /evidence="ECO:0000313|EMBL:KFV97685.1"
SQ SEQUENCE 521 AA; 60666 MW; 50B5E81A73E947AA CRC64;
LGLLYQEYRD KSTRQEIETR RLQDSQTDAE ENSPSEEIPS EEEPTSTTES KAPPQISLLR
NSNSRFNLWQ DLPEIQSSGV LSILQPDEIK LQEAMFELVT SEASYYKSLN LLVSHFMENE
RLKKILHQSE AHILFSNVLD VMAVSERFLL DLEQRVEENI VISDVCDIVY QHTVNHFSVY
ITYVSNQTYQ ERAYKQLLQD KPAFREVISQ LELDPKCKGL SFSSFLILPF QRITRLKLLV
QNILKKVEEK SDRETTALDA HKELETVVKA CNEGVRKMSR TEQMISIQKK LEFKIKSVPI
ISHSRWLLKQ GELQQMNGPK TSRTLRTKKL FREIYLFLFN DLLVICRQIP GDKYQVFDSA
PRGLLRVEEL EDQGQSLANV FILRLLENAD DREASYMLKA SSQSEMKRWM ISLAPNRRTK
FVSFTSRLVD CPQIQCVHPY VAQQPDELSL ELADVLNILD KTDDGWIFGE RLHDQERGWF
PSSMGEEILN PKIRAQNLKE CFRVHKSDDS QRRKLGSRNR Q
//
