ID A0A093LET3_FULGA Unreviewed; 2713 AA.
AC A0A093LET3;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Lysosomal-trafficking regulator {ECO:0000313|EMBL:KFW07581.1};
DE Flags: Fragment;
GN ORFNames=N327_07507 {ECO:0000313|EMBL:KFW07581.1};
OS Fulmarus glacialis (Northern fulmar).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Procellariiformes; Procellariidae;
OC Fulmarus.
OX NCBI_TaxID=30455 {ECO:0000313|EMBL:KFW07581.1, ECO:0000313|Proteomes:UP000053806};
RN [1] {ECO:0000313|EMBL:KFW07581.1, ECO:0000313|Proteomes:UP000053806}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N327 {ECO:0000313|EMBL:KFW07581.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KK603363; KFW07581.1; -; Genomic_DNA.
DR Proteomes; UP000053806; Unassembled WGS sequence.
DR CDD; cd06071; Beach; 1.
DR CDD; cd01201; PH_BEACH; 1.
DR Gene3D; 1.10.1540.10; BEACH domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR000409; BEACH_dom.
DR InterPro; IPR036372; BEACH_dom_sf.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR PANTHER; PTHR13743:SF163; LYSOSOMAL-TRAFFICKING REGULATOR; 1.
DR Pfam; PF02138; Beach; 1.
DR Pfam; PF14844; PH_BEACH; 1.
DR Pfam; PF00400; WD40; 2.
DR SMART; SM01026; Beach; 1.
DR SMART; SM00320; WD40; 5.
DR SUPFAM; SSF81837; BEACH domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50197; BEACH; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
DR PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000053806};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 1921..2027
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT DOMAIN 2032..2334
FT /note="BEACH"
FT /evidence="ECO:0000259|PROSITE:PS50197"
FT REPEAT 2524..2558
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 87..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 131..162
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..109
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 139..153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW07581.1"
FT NON_TER 2713
FT /evidence="ECO:0000313|EMBL:KFW07581.1"
SQ SEQUENCE 2713 AA; 305371 MW; 0A8518BD1D41A01B CRC64;
TSVGEETEWA LQGIRLLEAL LTICLHGAST MQQKIEVEMF HQSTCVDDIL LQIREQLAQS
KVIETDLAKP LFDSLLRVAL GTFSADQDHS EEKIEKTHYT EKEPLSQPGD ISEETEESQC
CSLKLFSEEE GYEADSESNP DDSETKNEGT DTKAEPGCTR PSGYFNDLAE NINQGELMYP
EICMLELNLL SAGNASLDVL AHVFQSCLKI ISQKERNATV LIEQGAVKHL LGGFLNILTQ
TESSFHACQM VLVDLLVSLM SSQTCSEELT LLLRIFLEKT PCTEILLKGV LKIIETNIYM
NPLQYLAFPL LHGTNLSSSS SQKSASTSSK TTGLLKRAKF SQSKKEADGE NLSHQLLSSW
HVAPIHLPLV GQNCWPHMSE GFSLSLWFHL ECAHETENST EKGKKIKRRS RLVAVRENSF
DSTEETKSLG TEYLSLGDKL VEDGCIHIIS LGSKALMIQV WADLNTGALI FRMCMDPNDE
MKAGLLAQAE SPDNVFLVGR WQHLAITYLQ QPEGKKNIHG KLLLWVSGQR KCEINLDYAL
PRKSSLSSDS NKTFCMIGHC TSSQEELLRL SGRWDLGNLL LFNGAKIGPE EAFYLYTCGP
DFTSVMPCKY GKTLTDCSKY ISKEILQCEQ IKELFMAKKE VDVGPLIESL AVVYTTCCPG
QYTIYEPVIR LKGQVKTVPS QRPFSSKEVQ SNVLDSQHLK TLQPVEYKTL QGILHEIGGT
GAFVFLFARV VEISSCEDTQ ALALQLILSL TKYNQQRIQE MDNCNGYSMI HRVLIKPKCI
VGFCMLKTLL EGCCSDEILC INENGQFMLD ADSTAVIQDV QLLEKLLLDW KIWSKAKEGV
WETLLAALEI LIRANHHQKM FNIKQLLKAQ VVHHFLLTCQ VLQEHKEGHL ASLPREVCRS
FVKIIEEVLG SPPDLELLTL VFNFLLAVHP PTNTYVCHNP TNFYFSLHID GKIFQEKVES
LMYLRNSSSG GKSIGSSAFV ITTPTGFTAL PLGGNTSKAS VQQKISFQVP KRLCKSLPAS
PISSPQVHPK RLTERIGRSV DDLHIIGKCD YIDFQGRTGF VGSSETIKRV QEELFLSSCE
SAKTACDSEL TSAEMFEDIA KEEELSENAF ESKEADADLK CNEGGGAAAE PLLCRPDNLK
GLPSFQKSQS NFAGLGLAFS VHGGSSAIAR WPSFADKNVL PEDWDSLAFS SANENTQKTS
ESPDDRCTED CLVLICCGLY DLLRGVLLLL PDIMLEDVMD KLIQPDYLIV LVNHPSPLIQ
QGVIKLLDAY FNRARREQKE KFLKNRGFSL LANQLYLHQG TQEVVECFLE MLFGRSVGLD
EEFDLEDVKN VGLFQKWCVI PVLGLIENSL YDNVLLHNCF CLLLQIINSC SKVADLLLDN
GLLYVLCNTL AALNGLETNI PLNDYKLLAC DIQQLLVAVA IHACSSSGSQ YFRVVEDLIV
LLGHLQNSKN ARMQNMAVVL QLRVLQAAIE LIKTTANQDA QEQAGSVPSP SAPHRAMFQK
RKGIAGSRKF SLAQSDALLI KMRSLASEEF NMMMQRRMSQ ENPIQATETE FIQRLQRLTV
LAVNRLIYLA STEECLDVLG ITETTSQSRL SASQLEVPEE ESQQELPNRT NPFLKEMFKM
LVEGIKVSIA TSRTNTPKQQ WKRILLSCKD TFRTQLGRLL VHNLSPARPL QERKQALEMV
HEVNHQEIMR DCLSPTLQHG PKLVLYLYEL MHNHSDEMTK EEKKAAGDFV NTLKCCGYKC
IPLSPRPKPG LMKALKEDQK KYEIEEGVNK AAWEKTMANN RQNLFQRLDT KSKDISKIAG
DITQAVSLSQ GIERKKVIQH IRGMYKAELS ASRHWQELVQ QLTHDRALWY DPVYYPTSWQ
LDPTEGPNRE RRRLQRCYLT IPNKYLLPDR QKQEGVIKTP LSYLFEDKTH SSHSSTVKDK
AASEHIRVNR RCISVAPSRE TAGELLLGKC GMYFVEDNAS DTIENSSFHG ETEPASFSWT
YEEIKEVHKR WWQLRDNAVE IFLTNGRTLL LAFDNTKVRD DVYHNILTNN LPNLLEYGNI
TALTHLWCTG QITNFEYLTH LNKHAGRSFN DLMQYPVFPF ILSDYTNETL DLNDSSVYRN
LVKPIAVQSK EKEDRYVDTY KYLEEEYRKG AREDDPMPPV QPYHYGSHYS NSGTVLHFLV
RLPPFTKMFL AYQDQSFDIP DRTFHSTNTT WRLSSYESMT DVKELIPEFF YLPDFLVNRE
GFDFGVRQNG DRVNHVNLPP WARNDPRLFI LIHRQALESD HVSQTICHWI DLVFGYKQKG
KASVQAINVF HPATYFGMDV SAVEDPVQRR ALETMIKTYG QTPRQLFHAA HVSRPGSRLI
MEGELPAAMG LLVQFAFRET REHTKEIIYP SPLPWIKGLK WGEYVGSPSA PDPVVCFSQP
HGERFGSLQA LPTKAICGLS RKFCLLMIYS KEQGVRSMHS TDIQWSAILS WGYADNILRL
KSKQSEPPVN FIQSSQFHQV TSCAWVPDSC QLFTGSKSGV ITAYMNRFTS NTPSEIEMES
QVHLYGHTAE ITSLFVCKPY SIMISVSKDG TCIIWDLNRL CYVQSLAGHK SPVTAVSASE
TTGDIATVCD SVGGGSDLRL WTVNGDLVGH VHCRESICSV AFSNQPEGVS VNVIAGGLEN
GVVRLWSTWD LKPVREITFS KSAKPIVSLT FSCDGHHLFT ANSDGNVIAW CRKDQQRLKL
PMFYSFLSSY AAG
//
