ID A0A093Q185_9PASS Unreviewed; 2387 AA.
AC A0A093Q185;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=ATP-binding cassette sub-family A member 2 {ECO:0000313|EMBL:KFW82738.1};
DE Flags: Fragment;
GN ORFNames=N305_07709 {ECO:0000313|EMBL:KFW82738.1};
OS Manacus vitellinus (golden-collared manakin).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Pipridae; Manacus.
OX NCBI_TaxID=328815 {ECO:0000313|EMBL:KFW82738.1, ECO:0000313|Proteomes:UP000053258};
RN [1] {ECO:0000313|EMBL:KFW82738.1, ECO:0000313|Proteomes:UP000053258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N305 {ECO:0000313|EMBL:KFW82738.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KL671500; KFW82738.1; -; Genomic_DNA.
DR STRING; 328815.ENSMVIP00005014965; -.
DR Proteomes; UP000053258; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF225; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 2; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:KFW82738.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053258};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..2387
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001886025"
FT TRANSMEM 626..648
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 669..691
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 703..725
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 732..753
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 812..833
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1744..1767
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1797..1818
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1824..1843
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1855..1880
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1939..1961
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 910..1141
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 2002..2237
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1144..1167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1249..1280
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1249..1263
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW82738.1"
FT NON_TER 2387
FT /evidence="ECO:0000313|EMBL:KFW82738.1"
SQ SEQUENCE 2387 AA; 267559 MW; EB759854D9E20DCB CRC64;
WVLAFEIFIP LVLFFILLGL RQKKPTIPVK EAFYTAAPLT SAGILPVMQS LCPDGQRDEF
GFLQYSNSTV TQLLEHLSEA VEQSSLFDPR HPGLEEELES LRRHLEALSS SEPSSMETHF
SSQTGSGFTL AWAAKDQGEL QRFLMQNMSL PNSTAELLLG SSIDLQEVDL RDGFGAGEKM
TWLEVRSGAA CREHGRAESI LLSHPHPTTE RSGGICPSRG AVMGPWATRR ERFAQLATEL
REQLDTPKIV SRLKLDEVNN TAAQHRLHAL LEDLVEMEKV LRDMDILSAL AKLLPRGACS
SRAPPPTANS TIPSWAGVGA AACSKGYWGW SRVGNLSPLC RTIEPEALKQ GNMSSLGFTS
KEQRNLGLLV HLMTSNPKIL YAPMGTEVDK VILKANETFA FVGNVTHYAK AWLNISPEIR
AYLEEGRLQR RIRWLQQFTA DLHKHPEILN VSDSDVLHNF LNGNFSLPNA SILLQQLDTI
DNAACGWVRF MAKVSVDIFK GFPDEESIVN YTLNQAYQDN VTVFASVIFQ TNRDGSLPPH
IMYKIRQNSS FTEKTNEIRR AYWRPGPNTG GRFYFLYGFV WIQDMMERAL INTFVGHDVV
EPGNYVQMFP YPCYTRDDFL FVIEHMMPLC MVISWVYSVA MMIQHIVTEK EHRLKEVMKM
MGLNNAVHWV AWFITGFVQL SISVTALTAI LKYGKVLMHS DVLIIWLFLA IYAVATIMFC
FLVSVLYSKA KLASACGGII YFLSYVPYMY VAIREEVAHD KITAFEKCIA SLMSTTAFGL
GSKYFALYEV AGVGIQWHTF SQSPVEGDDF NLLLSMMMLV VDAVVYGVLT WYIEAVHPGM
FGLPRPWYFP FQKSYWLGNG RVETWEWTWP WSHTTRLSIM EEDQACAMES RRLEETRGIE
EEPTHLPLVV CIDKLTKVYK TDKKLALNKL SLNLYENQVV SFLGHNGAGK TTTMSILTGL
FPPTSGSATI YGHDIRTEMD KIRKNLGMCP QHNVLFDRLT VEEHLWFYSQ LKSMAEEEIR
KEMDKMIEDL ELSNKRHCQV QTLSGGMKRK LSVAIAFVGG SRAVILDEPT AGVDPYARRA
IWDLILKYKP GRTILLSTHH MDEADLLGDR IAIISHGKLK CCGSPLFLKS TYGDGYKLTV
VKKQSDTRNS TEPGQPHSPL AHSSVSPCSE PRVSQFIKKY VASCLLISDT NTELSYILPS
EAVKKGCFER LFQHLEQSLE ELDLTSFGLM DTTLEEVFLK VSEEDQSLEN SDVDIKESKK
DALQPPTPEL GPKPEANGEP LAEAAMPEKP EVELSNLVTC SKLAQSQASL RSASSVGSVR
GDEGGAYSEF FGDYAPLFDN RQDPDNISLQ EVEAEDCDLA GQGSFKLEGS WLKLRQFHGL
IVKRFHCAKR NTKALFSQIL LPAFFVCVAM TVALSVPEIG DLPPLILSPS QYHNYTQPKG
NFIPYANEER HEYRIRLSPD ASPQQLVNTF HLPSGVGATC VLKTPFNNTL DQPMQTLNLN
SNESKMLAAK YFDAMCIDSF TQGLPLSNFV PPPPSPAPSD YPISVDEDLL RAWNSTTSAV
KGTVTSAPAL PRIIHEPIKC TCSMQGTGFS CPSGVGGHPP QMKVVTGDIL ADITGRNVSE
YLLYTSDRFR LHRQEGRLGG ICPAPYGALT FGNVQKSIPA SFGARAPAMV RKIAVRRTAA
VFYNNKGYHS MPTYLNALNN AILRANLPKS KGNPAAYGIT VTNHPMNKTS ASLSLDYLLQ
GTDVVIAIFI IVAMSFVPAS FVVFLVAEKA TKAKHLQFVS GCDPVIYWLA NYVWDMLNYL
VPATCCIIIL FVFDLPAYTS PTNFPAVLSL FLLYGWSITP IMYPASFWFE VPSSAYVFLI
VINLFIGITA TVATFLLQLF EHDKDLKVVN SYLKSCFLVF PNYNLGHGLM EMAYNEYINE
YYAKIGQFDK MKSPFEWDIV TRGLVAMTIE GFVGFFITIM CQYNFFRKPQ RLPVSTKPIE
DDIDVANERH RVLRGDADND MLKIENLTKV YKSRKIGRIL AVDRLCVGVR PGECFGLLGV
NGAGKTTTFK MLTGDETTTG GEAFINGHSI LKELLQVQQS LGYCPQFDAL FDELTAQEHL
ELYTRLRGIP WKDEERVVRW ALKKLELTKY ADKPASTYSG GNKRKLSTAI ALIGYPAFIF
LDEPTTGMDP KARRFLWNLI LDVIKTGRSV VLTSHSMEEC EALCTRLAIM VNGRLKCLGS
IQHLKNRFGD GYMITVRTKS SLNVKEVVRF FNRNFPEAVL KERHHTKAQY QLKSDQISLA
QVFSKMEQVV DVLGIEDYSV SQTTLDNVFV NFAKKQSDNL EQQETSPSCV LQSPLERLLS
LLRPRTAPTE LRALVVEEQE DLETDDEGLI SFEEERAQLS FNTDTLC
//
