ID A0A093QN16_PHACA Unreviewed; 508 AA.
AC A0A093QN16;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Ephexin-1 {ECO:0000313|EMBL:KFW87765.1};
DE Flags: Fragment;
GN ORFNames=N336_06095 {ECO:0000313|EMBL:KFW87765.1};
OS Phalacrocorax carbo (Great cormorant) (Pelecanus carbo).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Suliformes; Phalacrocoracidae;
OC Phalacrocorax.
OX NCBI_TaxID=9209 {ECO:0000313|EMBL:KFW87765.1, ECO:0000313|Proteomes:UP000053238};
RN [1] {ECO:0000313|EMBL:KFW87765.1, ECO:0000313|Proteomes:UP000053238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BGI_N336 {ECO:0000313|EMBL:KFW87765.1};
RA Zhang G., Li C.;
RT "Genome evolution of avian class.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KL419210; KFW87765.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093QN16; -.
DR Proteomes; UP000053238; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR CDD; cd01221; PH_ephexin; 1.
DR CDD; cd00160; RhoGEF; 1.
DR CDD; cd11939; SH3_ephexin1; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR035635; Ephexin-1_SH3.
DR InterPro; IPR047271; Ephexin-like.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR047270; PH_ephexin.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR12845:SF8; EPHEXIN-1; 1.
DR PANTHER; PTHR12845; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR Pfam; PF00169; PH; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR Pfam; PF00018; SH3_1; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00325; RhoGEF; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS50010; DH_2; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053238};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 90..274
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT DOMAIN 306..418
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 426..487
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 9..55
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 9..27
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 38..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KFW87765.1"
FT NON_TER 508
FT /evidence="ECO:0000313|EMBL:KFW87765.1"
SQ SEQUENCE 508 AA; 59044 MW; 694B78C6C0E0618C CRC64;
LGLLYQEYRD KSTRQEIETR RLQDSQTDAE ESSPSEETPS EAEPTSTTES KAPPQISLLR
NSNSRFNLWQ DLPEIRSSGV LSILQPDEIK LQEAMFELVT SEASYYKSLN LLVSHFMENE
RLKKILHQSE AHILFSNVLD VMAVSERFLL DLEQRVEENI VISDVCDIVY QHTVNHFSVY
ITYVSNQTYQ ERAYKQLLQD KPAFREVISQ LELDPKCKGL SFSSFLILPF QRITRLKLLV
QNILKKVEEK SDRETTALDA HKELETVVKA CNEGVRKMSR TEQMISIQKK LEFKIKSVPI
ISHSRWLLKQ GELQQMNGPK TSRTLRTKKL FREIYLFLFN DLLVICRQIP GDKYQVFDSA
PRGLLRVEEL EDQGQSLANV FILRLLENAD DREASYMLKA SSQSEMKRWM ISLAPNRRTK
FVSFTSRLVE IQCVHPYVAQ QPDELSLELA DILNILDKTD DGWIFGERLH DQERGWFPSS
MGEEILNPKI RAQNLKECFR VHKSDDSQ
//
