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Database: UniProt
Entry: A0A093R2B8_PHACA
LinkDB: A0A093R2B8_PHACA
Original site: A0A093R2B8_PHACA 
ID   A0A093R2B8_PHACA        Unreviewed;       708 AA.
AC   A0A093R2B8;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   08-JUN-2016, entry version 9.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
DE   Flags: Fragment;
GN   ORFNames=N336_03224 {ECO:0000313|EMBL:KFW90327.1};
OS   Phalacrocorax carbo (Great cormorant) (Pelecanus carbo).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Pelecaniformes; Phalacrocoracidae;
OC   Phalacrocorax.
OX   NCBI_TaxID=9209 {ECO:0000313|EMBL:KFW90327.1, ECO:0000313|Proteomes:UP000053238};
RN   [1] {ECO:0000313|EMBL:KFW90327.1, ECO:0000313|Proteomes:UP000053238}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BGI_N336 {ECO:0000313|EMBL:KFW90327.1};
RA   Zhang G., Li C.;
RT   "Genome evolution of avian class.";
RL   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-
CC       ATPase), a multimeric enzyme that catalyzes the translocation of
CC       protons across the membranes. Required for assembly and activity
CC       of the V-ATPase. {ECO:0000256|RuleBase:RU361189}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|RuleBase:RU361189}.
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DR   EMBL; KL426064; KFW90327.1; -; Genomic_DNA.
DR   Proteomes; UP000053238; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0015078; F:hydrogen ion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629; PTHR11629; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000053238};
KW   Hydrogen ion transport {ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053238};
KW   Transmembrane {ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    307    331       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    351    370       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    448    469       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    475    499       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    540    564       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM    677    704       Helical. {ECO:0000256|RuleBase:RU361189}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:KFW90327.1}.
FT   NON_TER     708    708       {ECO:0000313|EMBL:KFW90327.1}.
SQ   SEQUENCE   708 AA;  80735 MW;  00A8AC9B9E6EC655 CRC64;
     EKIENELKEI NTNQEALKRN FLELTELKFI LRKTQQFFDE AELHHQQMAD PDLLEESSSL
     LEPSEMGRGA PLRLGFVAGV INRERIPTFE RMLWRVCRGN VFLRQAEIEN PLEDPVTGDY
     VHKSVFIIFF QGDQLKNRVK KICEGFRASL YPCPETPQER KEMASGVNTR IDDLQMVLNQ
     TEDHRQRVLQ AAAKNIRVWF IKVRKMKAIY HTLNLCNIDV TQKCLIAEVW CPVADLDSIQ
     FALRRGTEHS GSTVPSILNR MQTNQTPPTY NKTNKFTCGF QNIVDAYGIG TYREINPAPY
     TIITFPFLFA VMFGDFGHGI LMTLIAVWMV LRESRILSQK SDNEMFNMVF SGRYIILLMG
     LFSTYTGLIY NDCFSKSLNM FGSSWSVRPM FSKGNWSDAL LETTPLLQLN PAIPGVFGGP
     YPFGIDPIWN IASNKLAFLN SFKMKMSVIL GIIHMLFGVT LSLLNHIYFK KPLNIYLGFI
     PEIIFMSSLF GYLVILIFYK WTAYDAHTSK DAPSLLIHFI NMFLFSYSDT SNKMLYKGQQ
     GLQCFLVVVA LLCVPWMLVA KPLVLRHQYL RRKHLGTHNF GGIRVGNGPT EEDAEIIQHD
     QLSTHSEEGE EFDFGDTVVY QAIHTIEYCL GCISNTASYL RLWALSLAHA QLSEVLWTMV
     IHIGLSVRSL GGGFGLFFIF AAFATLTVAI LLVMEGLSAF LHALRLHW
//
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