ID   A0A093XFJ5_9PEZI        Unreviewed;       654 AA.
AC   A0A093XFJ5;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 29.
DE   RecName: Full=Lysophospholipase {ECO:0000256|ARBA:ARBA00013274, ECO:0000256|RuleBase:RU362103};
DE            EC=3.1.1.5 {ECO:0000256|ARBA:ARBA00013274, ECO:0000256|RuleBase:RU362103};
GN   ORFNames=V490_05902 {ECO:0000313|EMBL:KFX91418.1};
OS   Pseudogymnoascus sp. VKM F-3557.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1437433 {ECO:0000313|EMBL:KFX91418.1, ECO:0000313|Proteomes:UP000029320};
RN   [1] {ECO:0000313|EMBL:KFX91418.1, ECO:0000313|Proteomes:UP000029320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-3557 {ECO:0000313|EMBL:KFX91418.1,
RC   ECO:0000313|Proteomes:UP000029320};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a 1-acyl-sn-glycero-3-phosphocholine + H2O = a fatty acid +
CC         H(+) + sn-glycerol 3-phosphocholine; Xref=Rhea:RHEA:15177,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:16870,
CC         ChEBI:CHEBI:28868, ChEBI:CHEBI:58168; EC=3.1.1.5;
CC         Evidence={ECO:0000256|RuleBase:RU362103};
CC   -!- SIMILARITY: Belongs to the lysophospholipase family.
CC       {ECO:0000256|ARBA:ARBA00008780, ECO:0000256|RuleBase:RU362103}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFX91418.1}.
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DR   EMBL; JPJS01001714; KFX91418.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093XFJ5; -.
DR   STRING; 1437433.A0A093XFJ5; -.
DR   HOGENOM; CLU_014602_0_0_1; -.
DR   Proteomes; UP000029320; Unassembled WGS sequence.
DR   GO; GO:0004622; F:lysophospholipase activity; IEA:UniProtKB-EC.
DR   GO; GO:0102545; F:phosphatidyl phospholipase B activity; IEA:UniProtKB-EC.
DR   GO; GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
DR   CDD; cd07203; cPLA2_Fungal_PLB; 1.
DR   Gene3D; 3.40.1090.10; Cytosolic phospholipase A2 catalytic domain; 1.
DR   InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR   InterPro; IPR002642; LysoPLipase_cat_dom.
DR   PANTHER; PTHR10728; CYTOSOLIC PHOSPHOLIPASE A2; 1.
DR   PANTHER; PTHR10728:SF33; LYSOPHOSPHOLIPASE 1-RELATED; 1.
DR   Pfam; PF01735; PLA2_B; 1.
DR   SMART; SM00022; PLAc; 1.
DR   SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR   PROSITE; PS51210; PLA2C; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|PROSITE-ProRule:PRU00555,
KW   ECO:0000256|RuleBase:RU362103};
KW   Lipid degradation {ECO:0000256|ARBA:ARBA00022963, ECO:0000256|PROSITE-
KW   ProRule:PRU00555};
KW   Lipid metabolism {ECO:0000256|PROSITE-ProRule:PRU00555,
KW   ECO:0000256|RuleBase:RU362103};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029320};
KW   Signal {ECO:0000256|RuleBase:RU362103}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|RuleBase:RU362103"
FT   CHAIN           20..654
FT                   /note="Lysophospholipase"
FT                   /evidence="ECO:0000256|RuleBase:RU362103"
FT                   /id="PRO_5005107657"
FT   DOMAIN          63..609
FT                   /note="PLA2c"
FT                   /evidence="ECO:0000259|PROSITE:PS51210"
SQ   SEQUENCE   654 AA;  69666 MW;  F466FF21EC26BB5B CRC64;
     MKILSGIVSL ATVAQVSYAT AIVAPRDGAH PDYAAVALVA ASELLSRGLP DSPTNGYAPG
     NVTCPATRPT IRVADGLSQN ETEWLPLRRN NTIDPMKDLL SRANIAGFDA GAYIEKHRNN
     ATALPNVGIA MSGGGYRALL NGAGFLAAAD SRTVNATGKG GIGGLLQSAT YLAGLSGGSW
     LVGSIYTNNF SSVATLQNGS PGSSVWKFGN SIFQGPEEDG LSILNTAEYY KDIKNQVDSK
     KNAGFEVSIT DYWGRALSYQ LINATDGGPA YTYSSIALQD NFKNGETPFP VIVADGRSPG
     DVIVSLNATV YEFNPFEMGS WDPTTYGFAP TRYLGSKFDG GKLPNSASCV RGFDNSGYVF
     GTSSTLFNQF LLGLNGTTSN LLTEVLASVL KDIGEANNDI AQYTPNPFWH YNPATNRDAE
     VTQLSLVDGG EDLQNIPLHP LIQPVRAVDV IFAVDSSADT EYFWPNGTAL VATYERSLNT
     TIGNGTSFPA VPDVNTFVNL GLNSRPTFFG CDAKNTTHLA PLVVYVPHAP YIAHSNVSTF
     DPAYDNTQRN LIIQNGYDVA TMGNGTVDAE WVTCVGCAIL SRSWDRTETK VPDACTTCFK
     RYCWDGSVNS TVPVNYNPEF KVAGVEEESA AGKVVPRKVI AMVVGVVVCG IMMA
//