ID A0A093XLJ2_9PEZI Unreviewed; 2191 AA.
AC A0A093XLJ2;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Carrier domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=V490_08126 {ECO:0000313|EMBL:KFX87624.1};
OS Pseudogymnoascus sp. VKM F-3557.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1437433 {ECO:0000313|EMBL:KFX87624.1, ECO:0000313|Proteomes:UP000029320};
RN [1] {ECO:0000313|EMBL:KFX87624.1, ECO:0000313|Proteomes:UP000029320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-3557 {ECO:0000313|EMBL:KFX87624.1,
RC ECO:0000313|Proteomes:UP000029320};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFX87624.1}.
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DR EMBL; JPJS01002446; KFX87624.1; -; Genomic_DNA.
DR STRING; 1437433.A0A093XLJ2; -.
DR HOGENOM; CLU_000022_6_2_1; -.
DR Proteomes; UP000029320; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR GO; GO:0044550; P:secondary metabolite biosynthetic process; IEA:UniProt.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 2.
DR Gene3D; 3.30.70.250; Malonyl-CoA ACP transacylase, ACP-binding; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 2.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR013120; Far_NAD-bd.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR030918; PT_fungal_PKS.
DR InterPro; IPR032088; SAT.
DR InterPro; IPR016039; Thiolase-like.
DR NCBIfam; TIGR04532; PT_fungal_PKS; 1.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF40; NORSOLORINIC ACID SYNTHASE STCA; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF07993; NAD_binding_4; 1.
DR Pfam; PF00550; PP-binding; 2.
DR Pfam; PF16073; SAT; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SMART; SM00823; PKS_PP; 2.
DR SUPFAM; SSF47336; ACP-like; 2.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 2.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000029320};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 283..721
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 1554..1629
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 1663..1741
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 264..283
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1520..1553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1632..1662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1752..1775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2191 AA; 240094 MW; 54789F9145D1DCE8 CRC64;
MAITCIYQLG SFISQAGTCE FAEKAGALGL CTGALAAAAV SCSGNILDLV PLSVDAVTAA
FRTGMLVADM AARVSPGKVG DSWSIIVSGS TSTEALNKFC EQTPLPLTSR PYVSVYTQNG
TTVSGKPEVL EKLLSCESFQ GLRNTRIPIY GPYHAPHLYS QHDITAIVEG LASVKYAMYQ
ERIPVLSSTG AKVERRNFAG LLRAAVEQIL LQPIRWSNII EDVQTCIHAV NPQAFTVVPF
GTCADQIIYS TIKETPLGSL INAVRTSRKP SDSPSTPYPN PKKPKLAIIG MSGRYPGAKD
NDAFWNVLHQ GLDMHKTVPE MHWDAKTHFD PTGTKKNTSA TEFGCWLDDP DLFDARFFNI
SPREAPQIDP AQRLALMTSF EAIEQAGIVP DATPSTRRDR VGVLYGVTSN DWMETNSAQN
IDTYFIPGGN RAFIPGRINY FFKFSGPSYA VDTACSSSLA AIHLACNSLW RGDIDTAIAG
GTNVLTNPDF TAGLDRGHFL SRTGNCKTFD DSADGYCRGE GVGTVIIKRL DDALADNDPI
LGVILGAYTN HSAESESITR PHVGAQRAIF NKILNQAGVD PYTVGYVEMH GTGTQAGDAG
EMLSVLDTFA PPLSEVKRGR NADEALYIGS AKANIGHGEA ASGVSSLIKV LLMMKKNIIV
PHCGIKTRIN RKFPTDLQER NVNIAFKPTA WDMSTGPNKP RRAFVNNFSA AGGNSALLIE
DAPERPEISR DATDLRSHHL IAVSAKSGVS IQGNLSTMLR FLKENPDVSL AELSYTTTAR
RIHNQHRVLL CGSNVKSLCN QIETSLQNKA GVTRAKNTPK VVFAFTGQGA QYPGMGRQLF
ESFSVFRTEM NRLDHITQSL GFPSVLPLIQ SEEQDVDIFE PLVVQLASVC MQIATSKLWA
AWNITPTTVV GHSLGEYAAL NVAGVLSDAD AIYLVGTRAT LLQQKCTRNT HAMLVVKASV
DEIAQTLPNG SYEISCINSP RETVLAGKIE GITRLKDLLA EAGTKSIFMK VPYAFHSSQI
EPLLSDFTIA ASCVSYLEPN IPVLCPLDGN VVEEHGNFNA EYLARHARES VNMRKALAAG
HKQRLISDQT VVLEVGPHPA VSGMVRAEFS QQVTTLATLQ RGRDMWPVLG ASLQWLYVSG
ASINWTEYHR DFKGSHKVLS LPSYSWDLKP FWMQYVNDWS LRKGDPPMVI NSALSLESTT
IHRIVKETGD SQKTYIVVEA DITREDLSPL VQGHEVDGIP LCTPSVYADI ALSLGSYLLK
RYQPAQKESL VDVSDMTVSK ALILQPNVTQ QLLQAHSDID WSNNCASTKF MSFDSKQKLQ
EHARCVLRFK SHELQGILQA DAANVKKKMQ ALRDGIALET SARFNRPMVY RAIRPLARFH
DDYRAIDEVV LNSTTLEASS QLSFGSVKRA GNFHTHPAII DSLTQSCGFT MNCNDSSDLD
TEVFMNHGWG SLQIFEPMDF EKKYTTYTRM SQGPDKLWHG DVVIFNDDKV VAFFSQIAIQ
GVPRRVLKVI LSLESGRKTQ KQQLAQTTSQ PAFEAKPTAS NLHTSSPNNQ GPQAAKLNMA
LTIIAEESGL AVSDLSDTTV FSEVGIDSLL GLTISTRFRE ELDLDLEFNA MFYDYPTVGD
LKLFFGDAEP SGTPISSSST SFDDTASPTS TAGATTPSNG EGASCELDFQ SVLAIISEES
GIAMEELAED TNFADSGVDS LLSLVIVSRL RDELEFDIQH ESLLLECPTV GDLRRLLLGD
VLSGNPVKFD LPIEPEVPEG TKTQGGASTT VDESPVRTEK EILALDTRKQ AVDELVQKYT
ASFAVSGPSQ KSITASENET VVLVTGASGS LGSHLVYHFA QLPDVKRVVC LNRENKVDPY
LRQRKAMRDK GIRFPEALEN KLLVLQTDIT KPMLGLPSDV YKSLTTSVTH LIHNAWPMSA
KRDLAGFEPQ FQSMRNLIDF GCHVISCRSS SFKFSFQMVS SIGVVGHYGL GTGETRTMVP
EDRMSIDAVL PNGYGEAKWG CERMLDETLH KHASHFRSMV VRLGQIAGSK TSGYWNPMEH
FGFLLKSSQT LNALPDVDGD VFWTPVNDIA EILSDLILSN RTPHHIYHIE NPVGQTWKEI
NAILSNALNI PNLIPFTEWL ERVRAAPHRK NPAATLLEFL ESNYLRMSCG GLILDTHHTL
QHSKTLLAIG PVSEEVVRKY IHIWKEIGFL D
//
