ID   A0A093XS91_9PEZI        Unreviewed;       999 AA.
AC   A0A093XS91;
DT   26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT   26-NOV-2014, sequence version 1.
DT   24-JAN-2024, entry version 39.
DE   RecName: Full=Glycosyl hydrolase family 30 TIM-barrel domain-containing protein {ECO:0000259|Pfam:PF02055};
GN   ORFNames=V490_04869 {ECO:0000313|EMBL:KFX93352.1};
OS   Pseudogymnoascus sp. VKM F-3557.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX   NCBI_TaxID=1437433 {ECO:0000313|EMBL:KFX93352.1, ECO:0000313|Proteomes:UP000029320};
RN   [1] {ECO:0000313|EMBL:KFX93352.1, ECO:0000313|Proteomes:UP000029320}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VKM F-3557 {ECO:0000313|EMBL:KFX93352.1,
RC   ECO:0000313|Proteomes:UP000029320};
RA   Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA   Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA   Ozerskaya S.M.;
RT   "Population genomics of a fungus Geomyces pannorum provides evidence of
RT   horizontal gene transfer but not of sexual reproduction.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC       {ECO:0000256|ARBA:ARBA00005382, ECO:0000256|RuleBase:RU361188}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KFX93352.1}.
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DR   EMBL; JPJS01001362; KFX93352.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A093XS91; -.
DR   STRING; 1437433.A0A093XS91; -.
DR   HOGENOM; CLU_315259_0_0_1; -.
DR   Proteomes; UP000029320; Unassembled WGS sequence.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR   CDD; cd14688; bZIP_YAP; 1.
DR   Gene3D; 1.20.5.170; -; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 2.
DR   InterPro; IPR046347; bZIP_sf.
DR   InterPro; IPR021833; DUF3425.
DR   InterPro; IPR001139; Glyco_hydro_30.
DR   InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR   PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR   Pfam; PF11905; DUF3425; 1.
DR   Pfam; PF02055; Glyco_hydro_30; 2.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF57959; Leucine zipper domain; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|RuleBase:RU361188};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361188};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029320};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          141..258
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF02055"
FT   DOMAIN          287..450
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF02055"
FT   REGION          532..580
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          725..746
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          977..999
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        535..549
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        558..580
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   999 AA;  110603 MW;  B11657BF9FBE2519 CRC64;
     MKEMQIKSLP VNASHMARVP DMSIVARMHK LRARWLAGHR RDRKKARHAA RRRVPPRNKG
     TYGYYIAKMK YQAVLVAELL TFVFSTGVVG VSSPASWATS SDGVYKLSSF DAPVKGAGDA
     GGASTWEIQV DDTSSGHKQS ITGFGAAVTD ATVTAFSALS DSQKTALLAD LLTTSTDDGV
     AFNLFRHTIA ASDLSGTVYA YSDEVDLELA NFDLKTEGKD MLSWLAQFKA VNSAIKVLGS
     TWSPPGWMKL NGVMDGTTTD NNLDHKGRRR CRRDYHPERA QAGYPTMYVA ADESTSLIQN
     NIGPALKDAG LSTEIWAYDH NTDVPAYPQA VLDGAGSFVN TVAWHCYAQN NDWAALTTFH
     EKNPNVVQYQ TECWTSPTNS WYSTIDFVMG PMQNWAAGSI AWTLGSDTNN GPHLPGGCSS
     CRGLIVVDTG AGTYSKTLDY YLMGQFSRFV PRGATALATT GSQDFGGGQK FEAVSFVEED
     GSRTVVIQNN FGNEVFLTVT FKGGETWSGT VYTESLTTWQ LPPARVYLPH GASAMSEKTS
     RSSRGKGDGT GFSRQHLSAA HLEKRRMADR ESQRAGRERT KNHIRHLEKL VESLQKTEDN
     DRLEALMVQC QELRGQNEQL MSVISNIGRM CKTIEHPNET QARIGHSPGA GLKTSMGPDF
     HQQPPQGGIV GGDIHPYVPA HEDQHETWWH QNGMGEMDEI HQVPSNPMLP CLDTSLPILN
     SSAQTPANSI QSHNTVPRTF GPPEASTETT AEVVNDILSK AELFTVLSTQ PEKDADIAIR
     AVLNGWNSVR QTETLDDGWE SICKVDQQAF ISCGLIERLA ILQVMRLKLR HAIEPTSENL
     ERLPTFMHPR PTQNLIQHPT MVDYFVWPDL RDLLILSPYQ SMKSADVVKF VSIFVKSIRF
     QWPYDLCDSF TKNPHSGLFS FSNAFYKQFE DIRSWMLDSD FFVMCPQMIG YIPIHNPGPG
     RDLGGFLDQG HYLEEATGQD QKPHGNTDEP DWTDVLMPT
//