ID A0A093YAS6_9PEZI Unreviewed; 589 AA.
AC A0A093YAS6;
DT 26-NOV-2014, integrated into UniProtKB/TrEMBL.
DT 26-NOV-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Xanthine/uracil permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=V490_01640 {ECO:0000313|EMBL:KFX99822.1};
OS Pseudogymnoascus sp. VKM F-3557.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Leotiomycetes incertae sedis; Pseudeurotiaceae; Pseudogymnoascus.
OX NCBI_TaxID=1437433 {ECO:0000313|EMBL:KFX99822.1, ECO:0000313|Proteomes:UP000029320};
RN [1] {ECO:0000313|EMBL:KFX99822.1, ECO:0000313|Proteomes:UP000029320}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=VKM F-3557 {ECO:0000313|EMBL:KFX99822.1,
RC ECO:0000313|Proteomes:UP000029320};
RA Leushkin E.V., Logacheva M.D., Penin A.A., Sutormin R.A., Gerasimov E.S.,
RA Kochkina G.A., Ivanushkina N.E., Vasilenko O.V., Kondrashov A.S.,
RA Ozerskaya S.M.;
RT "Population genomics of a fungus Geomyces pannorum provides evidence of
RT horizontal gene transfer but not of sexual reproduction.";
RL Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KFX99822.1}.
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DR EMBL; JPJS01000436; KFX99822.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A093YAS6; -.
DR STRING; 1437433.A0A093YAS6; -.
DR HOGENOM; CLU_024508_3_2_1; -.
DR Proteomes; UP000029320; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029320};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 100..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 143..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..205
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 323..343
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 363..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..447
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 459..485
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 546..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 574..589
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 589 AA; 62642 MW; 4FF9DC08BEAD511F CRC64;
MKDYGKIIND RVARSFVGRR FRLEGSGHRY ERKDSRFLTE IRAGLATFFA MAYIISVNSG
ILTDSGGPCE CPAGMTSCDD DPGYQSCLAI IHRDFVTGTA AIAALTSVMM GLCANMPIAL
APGMGLNAYF TYTVVGFHGS GPVSYNLALT AVFVEGLVFV GLSLLGLRQW LARSIPGSIK
LASSVGIGLY LTIIGLGYSA GIGLITGAQD TPVELAGCVA SAMVDGLCPN STKMRSPTMW
IGIFCGGMLT ALLLMYRVKG AIIAGIAVVA ITSWPRNSAV TYFPHTPAGD EMFDFFKQVV
TFHPIEKTLN VLHWNLKGAS GQFGLAFITF LYVDIMDCTG TLYSMAHLAG AIDPVTQDFE
GSAVAYLVDA FGITIGSLFG LSPVTAFIES GAGISEGGKT GITAITSGIC FFISIFFAPI
FASIPPWATG CTLVIVGSMM CKAAAAINWR YPGDAIPAFV TLAVMPFTYS IAYGLIGGIV
TYAIINTTVW IIEKASGGRW VPPGKIHKEP WTYKLVGGVL PPWVVRAARG KRDFWHEDDE
VVEMAGVSRD GSSDGKPEGN LDATPTSEVL PAKGEAYRDT EAKTHDHAL
//
